Human Anatomy and Physiology : Human Anatomy and Physiology

Study concepts, example questions & explanations for Human Anatomy and Physiology

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Example Questions

Example Question #36 : Musculoskeletal System

which test would be used to determine an anterior cruciate ligament (ACL) rupture?

Possible Answers:

Posterior drawer

Lachman's

McMurray's

Godfrey's (90-90)

Quadriceps active test

Correct answer:

Lachman's

Explanation:

A Lachman's test requires the clinician to apply an anterior force on the tibia, looking for an end-feel (or resistance created by the ACL). Godfrey's (90-90), posterior drawer and quadriceps active test all test for a rupture, or sprain of the posterior cruciate ligament (PCL). McMurray's tests for meniscal tear.

Example Question #37 : Musculoskeletal System

Which structure(s) would have a tensile force applied with hyperflexion of the knee?

Possible Answers:

Medial collateral ligament (MCL) & lateral collateral ligament (LCL)

Medial collateral ligament (MCL)

Lateral collateral ligament (LCL)

Iliotibial band (ITB) and medial collateral ligament (MCL)

Anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL)

Correct answer:

Anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL)

Explanation:

The anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) are both affected with hyperflexion of the knee, as these two ligaments are located deep inside the knee capsule, and prevent anterior and posterior sheering forces. If this action occurred with enough force, these structures would be injured. The sedial collateral ligament (MCL) and lateral collateral ligament (LCL) would be injured with a valgus or varus force, both with occur in the coronal plane. The iliotibial band (ITB) and and medial collateral ligament (MCL) would require multiplaner forces in order to be injured. 

Example Question #41 : Musculoskeletal System

A patient in your clinic complains of knee pain, and demonstrates a positive lever sign. The positive lever sign suggests what structure is injured?

Possible Answers:

Lateral meniscus

Posterior cruciate ligament

Anterior cruciate ligament

Medial meniscus

Correct answer:

Anterior cruciate ligament

Explanation:

Although it is a very new test, the available literature suggests that the lever sign has superior diagnostic value to the Lachman, pivot-shit, and anterior drawer tests, to detect anterior cruciate ligament (ACL) injuries. Additionally, the preliminary evidence suggests that the lever sign has high diagnostic value for both acute and chronic ACL injuries. 

Example Question #1501 : Human Anatomy And Physiology

Since ATP regeneration occurs through oxidative phosphorylation, we are able to calculate ATP usage during exercise by tracking the volume of oxygen flow in a test subject, and calculating the amount of oxygen used. This method of indirectly measuring ATP usage during exercise requires use to know the ratio of high energy phosphates (ATP) generated per unit of oxygen (O2).

What is the typical production ratio of high energy phosphates (ATP) per unit of oxygen (O2)?

Possible Answers:

32 ATP per O2

1.5 ATP per O2

6.3 ATP per O2

None of the answers are correct.

3 ATP per O2

Correct answer:

6.3 ATP per O2

Explanation:

Oxidative phosphorylation generates roughly 6.3 high energy phosphates (ATP) per unit of oxygen (O2).

It is also important to note that ATP generation occurs anaerobically via lactic acid production, with the ratio being 1.5 high energy phosphates (ATP) per unit of lactate. But this is not the correct answer in this context.

Example Question #1 : Immune System

Which of the following is a sign of inflammation?

Possible Answers:

Dizziness

Calor

Impaired vision

Ataxia

Correct answer:

Calor

Explanation:

Calor—or redness—is associated with increased blood flow, which can result from inflammation. During an inflammation response, histamine release results in vasodilation and increased bloodflow, which can cause the infalmmed area to appear red.

Example Question #1 : Immune System

What type of microbiota infect individuals who are already immunocompromised?

Possible Answers:

Opportunistic microbiota

Pathogens

Transient microbiota

Resident microbiota

Correct answer:

Opportunistic microbiota

Explanation:

Opportunistic microbiota can form biofilms and affect patients who are immunocompromised, suchs as someone with AIDS or a chronic illness.

Resident microbiota are always present in the body and frequently have mutualistic relationships with their human hosts. Transient microbiota are present at some times, but absent at others. Pathogens affect healthy individuals, as well as those who may be immunocompromised.

Example Question #2 : Immune System

Which of the following does not release histamine?

Possible Answers:

Neutrophil

Mast cell

Platelet

Basophil

Correct answer:

Neutrophil

Explanation:

Mast cells are perhaps the best-known producers of histamine. Basophils also release histamine and contribute to the inflammatory response, while platelets are also capable of releasing histamine. Neutrophils are best-known for their phagocytic properties, and do not produce histamine.

Example Question #3 : Immune System

Which of the following causes edema during inflammation?

Possible Answers:

Increased oncotic pressure in the venules

Increased hydrostatic pressure in the arterioles

Decreased hydrostatic pressure in the venules

Increased oncotic pressure in the arterioles

Correct answer:

Increased hydrostatic pressure in the arterioles

Explanation:

There are two primary types of pressure: hydrostatic pressure is the result of fluid volume pressing on a physical boundary, while oncotic pressure is the pulling force of protein concentrations causing watter diffuse across a membrane. During an inflammation response, fluid is allowed to leak out of arterioles and capillaries resulting in increased hydrostatic pressure in the interstitium. Edema is the accumulation of fluid in the interstitium.

All the other answers cause fluid to return to the vessel, rather than exit it.

Example Question #4 : Immune System

Which of the following do NSAIDS effect?

Possible Answers:

COX-1 

Lipoxygenase

Phospholipase C

Leukotriene

Correct answer:

COX-1 

Explanation:

NSAIDs inhibit COX-1, inhibiting the formation of prostanglandins.

Example Question #4 : Immune System

What is sarcoidosis?

Possible Answers:

A form of cancer

A digestive disorder that leads to irritable bowels

A disorder of the immune system cells that cause inflammation which leads to the formation of granulomas

Another term for tuberculosis

Correct answer:

A disorder of the immune system cells that cause inflammation which leads to the formation of granulomas

Explanation:

Sarcoidosis is a disease of unknown cause that leads to inflammation. The immune cells that cause inflammation do not dissipate and instead, create clusters called granulomas. Not all cases of sarcoidosis require treatment.

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