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Example Questions
Example Question #1 : Reaction Types
Which of the following statements is true concerning the Hofmann elimination reaction?
Possible Answers:
The Zaitsev product is favored in the elimination reaction
The least substituted alkene is the major product in the reaction
The quaternary ammonium salt is a poor leaving group
The ammonium is eliminated following an E1 mechanism
Correct answer:
The least substituted alkene is the major product in the reaction
Explanation:
The Hofmann product is the most favored product in a Hofmann elimination reaction. The reaction follows an E2 mechanism, where a quaternary ammonium salt is able to be removed from a hydrocarbon, resulting in an alkene product. This reaction results in the least substituted alkene being the primary product.
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