Genetics : Genetics

Study concepts, example questions & explanations for Genetics

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Example Questions

Example Question #17 : Genetic Engineering

Suppose the trait of hair color has incomplete dominance.

If a person with blonde hair and a person with black hair produces an offspring, what will be a likely hair color of the offspring?

Possible Answers:

patches or strands of pure black hair and of pure blonde hair

light brown

black

blonde

Correct answer:

light brown

Explanation:

Incomplete dominance is where two traits intermix together, usually to create some kind of in-between trait. With blonde hair and black hair, the offspring will likely have a hair color that will be between the two extremes — likely brownish hair. There will be patches or strands of pure blonde and pure black hair in the offspring if hair trait was co-dominant, but it states in the problem that hair color trait has incomplete dominance. It may also be possible that the child will have only blonde hair or only black hair, but this is less likely and also will not be demonstrating the concept of incomplete dominance, as the question is asking for. Any of the other answers are equally likely to occur since the two parents have very different hair colors.

Example Question #18 : Genetic Engineering

Suppose fur color expresses incomplete dominance. Pure fur colors are blue (BB) and pink (PP). A monster with a genotype of Bb will have the incomplete dominance of purple fur.

What will be the phenotypic ratio of the offspring of a purple parent monster and a pink parent monster?

Possible Answers:

purple : pink

2 : 2

purple : pink : blue

1 : 1 : 2

purple : pink : blue

1 : 2 : 1

purple : pink : blue

2 : 1 : 1

Correct answer:

purple : pink

2 : 2

Explanation:

It can be seen that the phenotypic ratio of the offspring will be purple : pink of 2 : 2. This can be seen by doing a Punnett square and keeping in mind that fur color in this problem has incomplete dominance.

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Example Question #19 : Genetic Engineering

Suppose a venus flytrap plant has sharp teeth and red leaves. Sharp teeth (T) is dominant to blunt teeth (t). Red leaves (R) is dominant to purple leaves (r).

Is it possible that two venus flytrap plants both with sharp teeth and red leaves have an offspring with blunt teeth and purple leaves?

Possible Answers:

No, since both parents express dominant traits, it is not possible for the offspring to express recessive traits even if the offspring have only recessive alleles.

Yes, because it is possible that both the parent venus flytrap plants carry the recessive alleles for blunt teeth and purple leaves.

Yes, because although both parents express dominant traits, the phenotype of the offspring is determined completely by chance alone and not by the parents' genetics.

No, because both parents express dominant traits, it means that they can only be carrying dominant alleles, and that only these dominant alleles can be passed to the offspring.

Correct answer:

Yes, because it is possible that both the parent venus flytrap plants carry the recessive alleles for blunt teeth and purple leaves.

Explanation:

It is possible for the parents to have genotypes that contain recessive alleles that will yield an offspring with the recessive traits. This can be seen by doing a dihybrid cross of the two parents both with genotypes of TtRr (which would express sharp teeth and red leaves; additional note: both parents HAVE to have this genotype in order to have an offspring with the recessive traits of blunt teeth and purple leaves — please refer to the Punnett square to see why).

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Example Question #19 : Genetic Engineering

How are restriction enzymes named?

Possible Answers:

from the organism they’ll be added to

from the organism they were taken from

from the name of the experiment

randomized naming

from the scientist that discovered them

Correct answer:

from the organism they were taken from

Explanation:

Restriction enzymes are named from the organism they were taken from. They function to cut DNA in bacteria, a crucial step in the process of sequencing DNA, as you need it to be broken down into smaller segments.

Example Question #1 : Laboratory Procedures And Important Historical Experiments

In order to amplify the following DNA sequence using PCR, what is an acceptable pair of oligonucleotide primers? (only the sense strand is shown)

ATGATCAGGCTAAATGCTAGTTTACCGGATGAGCAATGACGCGTACCATATAGGCATATCCGATGCCATGATGGCCTACGGATCA

Possible Answers:

Forward: 5' ATGATCAGGCTAAATGCTA 3'

Reverse: 5' ACTAGGCATCCGGTAGTACC 3'

Forward: 5' ATGATCAGG 3'

Reverse: 5' ACTAGGCATC 3'

Forward: 5' ATGATCAGG 3'

Reverse: 5' TGATCCGTA 3'

Forward: 5' ATGATCAGGCTAAATGCTA 3'

Reverse: 5' TGATCCGTAGGCCATCATGG 3'

Forward: 5' ATGATCAGGCTAAATGCTA 3'

Reverse: 5' CCATGATGGCCTACGGATCA 3'

Correct answer:

Forward: 5' ATGATCAGGCTAAATGCTA 3'

Reverse: 5' TGATCCGTAGGCCATCATGG 3'

Explanation:

There are two primary factors that influence the quality of a polymerase chain reaction (PCR) primer. The first is length. The primer should ideally be roughly 18-30 bases in length; this qualification can be used to rule out two of the possible given answer options. The second factor is the melting point of the primer. An ideal oligonucleutide sequence will have a relatively high cytosine/guanine content. These particular bases form three hydrogen bonds in the DNA molecule, while adenine and thymine form only two. Cytosine and guanine interactions thus require more energy to break, and raise hte melting point of the sample. The process of PCR requires heating the sample at certain points, which can become a problem for primers with high adenine/thymine content.

Our ideal answer will be a longer sequence (18 bases) with a high percentage of cytosine and guanine residues.

Example Question #2 : Laboratory Procedures And Important Historical Experiments

Which of the following scientists first discovered the concepts behind dominance, segregation, and independent assortment?

Possible Answers:

Charles Darwin

Louis Pasteur

Rosalind Franklin

Gregor Mendel

Correct answer:

Gregor Mendel

Explanation:

It was Gregor Mendel who did studies on pea plants to first described the concepts behind genetic inheritance. By breeding pea plants with different visible phenotypes and observing the phenotypes of the offspring produced, he was the first scientist to provide rules for heredity (now known as Mendelian inheritance). 

Example Question #3 : Laboratory Procedures And Important Historical Experiments

What is the name of the laboratory procedure by which a small amount of DNA can be made into many more copies through the use of DNA polymerases and heat cycling?

Possible Answers:

Polymerase chain reaction

Reverse transcription

Southern blotting

Western blotting

Molecular cloning

Correct answer:

Polymerase chain reaction

Explanation:

Polymerase chain reaction (PCR) is a method by which a specific sequence of DNA can be copied and replicated many times over in a test tube, which has been of enormous importance to the field of molecular biology. The other techniques listed all are important in molecular biology as well, but are typically for detection or other manipulations, not replication. 

Example Question #4 : Laboratory Procedures And Important Historical Experiments

What is the name of the method that allowed Watson and Crick to propose the double-helix structure of DNA?

Possible Answers:

X-ray crystallography

Genetic recombination

Pulse-chase analysis

Polymerase chain reaction

Ethyl methanesulfonate mutagenesis

Correct answer:

X-ray crystallography

Explanation:

Watson and Crick crystallized DNA to be able to visualize the structure, and it was this finding that led them to propose the double helix. Fun fact: Rosalind Franklin's work was essential to this finding as she was the expert in x-ray crystallography, but Watson and Crick are traditionally given all the credit. 

Example Question #5 : Laboratory Procedures And Important Historical Experiments

Choose the correct answer:

In 1928, microbiologist Frederick Griffith demonstrated that bacteria can take up foreign DNA from the environment by a process known as __________.

Possible Answers:

transfection

transformation

translocation

heat shock

Correct answer:

transformation

Explanation:

This process is known as transformation. It was discovered after Griffith heat treated bacteria (to destroy their virulence) and noticed that mice injected with the heat-killed bacteria and a living, non-virulent strain would die of infection.

Example Question #6 : Laboratory Procedures And Important Historical Experiments

Chose the correct answer:

American geneticist Thomas Hunt Morgan is best known for __________.

Possible Answers:

being the first person to definitively link the inheritance of a specific trait with a particular chromosome

explaining the relationship between DNA and protein production

being the first person to isolate hereditary material

explaining semi-conservative DNA replication

Correct answer:

being the first person to definitively link the inheritance of a specific trait with a particular chromosome

Explanation:

In 1910, Thomas Hunt Morgan performed a test cross between white-eyed male Drosophila and homozygous red-eyed females to test the frequency of white eyes in the subsequent generations. The F1 generation all had red eyes, but when Morgan crossed the F1 generation, he noticed a 3:1 ratio of red to white eyes in the F2 generation. In all of his experimements, the white-eyed F2 flies were always male. Subsequent experiments supported the hypothesis that the white-eye trait was sex-linked (in this case, to the X chromosome).

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