AP Biology : Cellular Biology

Study concepts, example questions & explanations for AP Biology

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Example Questions

Example Question #261 : Cellular Biology

__________ are surveillance mechanisms that halt the progress of the cell cycle if any of the various events involved not working correctly or are not happening in the correct order.

Possible Answers:

Chaperones

Monitors

Activation energies

Checkpoints

Allosteric inhibitors

Correct answer:

Checkpoints

Explanation:

Checkpoints are what monitor and control the process of the cell cycle and lower incidence of problems with cell growth and replication. The major three checkpoints in the cell cycle are the checkpoint before the S phase at the end of G1 phase to check for DNA damage. The second checkpoint is in the G2 phase before the M phase. The third major checkpoint in the cell cycle in at the end of M phase before anaphase occurs. Checkpoints are the points of control in the cell cycle regulation that are regulated by cyclin dependent kinases and cyclin levels; each checkpoint has its unique cyclins.

Example Question #33 : Cellular Division

Which of the following is a trait unique to cancer cells?

Possible Answers:

They have escaped form cell cycle controls and inhibitions

Density-dependent growth factors limit their division

They do not use glucose as an energy source

They do not undergo interphase

They communicate with other cells through chemical signalling

Correct answer:

They have escaped form cell cycle controls and inhibitions

Explanation:

Cancer cells are not controlled by cyclins and cyclin-dependent kinases, which regulate the cell cycle. They would not proceed through interphase if the system of checkpoints was still in place. The system of chemical signaling is mostly destroyed, preventing the cancer cells from being controlled by surrounding normal cells. Cancer cells, like virtually all body cells, utilize glucose for energy.

Example Question #262 : Cellular Biology

What is the correct order of the cell cycle?

Possible Answers:

G1, G2, M, S

S, G1, G2, M

G1, G2, S, M

G1, S, M, G2

G1, S, G2, M

Correct answer:

G1, S, G2, M

Explanation:

G1 (gap 1 phase) is the first stage of the cell cycle. Growth and some preparation for cell division occurs in this stage. If the cell is not preparing to divide then it enters the G0 stage (gap 0 phase): the resting gap stage where neither growth nor division occurs. The S stage (DNA Synthesis phase) comes next and there chromosome duplication occurs. G2 (gap phase 2) is after the S stage and there cell growth continues and everything is checked to make sure the cell can divide. Finally, M stage (mitotic stage) is last and there mitosis occurs and two new daughter cells begin the cell cycle again. Keep in mind that at the end of each stage there are "checkpoints" that the cell needs to pass in order to keep going forward. Cancer occurs when a cell bypasses those checkpoints and continues to replicate without those controls.

Example Question #34 : Understanding The Cell Cycle

When does chromosome duplication occur?

Possible Answers:

Prophase

G0 Stage

Prometaphase

Metaphase 

Interphase

Correct answer:

Interphase

Explanation:

It is important to note that chromosome duplication happens before mitosis, so interphase is correct. More specifically, it happens in the S stage of interphase.Cell cycle

Example Question #264 : Cellular Biology

In which of the following cell cycle phases does DNA replication occur?

Possible Answers:

G1 phase

G2 phase

M Phase

S phase

G0 phase

Correct answer:

S phase

Explanation:

The "S" phase, known as the synthesis phase, is the portion of the cell cycle where DNA is replicated. The other stages listed do not contain DNA replication. G0 is a cell cycle arrest phase, where a cell remains dormant, awaiting signals to re-enter the cell cycle.

Example Question #34 : Cellular Division

Which of the following terms is used to describe programmed cell death?

Possible Answers:

Necrosis

Procaspases

Caspases

Apoptosis

Anaphase

Correct answer:

Apoptosis

Explanation:

Caspases are proteases that initiate apoptosis. Procaspases are inactive caspases that are stored in the cell. Necrosis is when the cell body dies due to cell injury. Apoptosis is programmed cell death. The cell uses it to control the rate of cell division. Anaphase is a phase in the cell cycle in which the chromosomes are pulled to opposite poles of the cell.

Example Question #1 : Understanding Mitosis

How is metaphase of mitosis defined? 

Possible Answers:

Chromosomes move towards the center or equator of the cell. Chromatids have not separated.

DNA begins to replicate.

Centrioles begin to move towards opposite poles of the cell.

Sister chromatids begin to separate and form independent chromosomes.

Two distinct cells begin to form and separate from one another.

Correct answer:

Chromosomes move towards the center or equator of the cell. Chromatids have not separated.

Explanation:

Metaphase is defined when chromosomes move towards the equator of the cell.

Other answers refer to other stages of mitosis. Sister chormatids separate during anaphase, two distinct cells form during telophase, centrioles move towards opposite poles of the cell during prophase, and DNA replication happens during interphase.

Example Question #41 : Cellular Division

During which phase of mitosis do sister chromatids separate?

Possible Answers:

Telophase

Anaphase

Metaphase

Prophase

Correct answer:

Anaphase

Explanation:

During anaphase, the third stage of mitosis, the spindle fibers cause sister chromatids to break apart, and they are subsequently moved to opposite sides of the cell.

Chromosomes condense during prophase, align during metaphase, separate during anaphase, and are relocated during telophase.

Example Question #2 : Understanding Mitosis

During which phase of mitosis do chromatids condense?

Possible Answers:

Anaphase

Telophase

Prophase

Metaphase

Correct answer:

Prophase

Explanation:

Chromatids condense during prophase, the first stage of mitosis. This allows the abundant amount of DNA to be organized into relatively small and tightly packed structures that can be aligned and separated later in mitosis. This also signifies the conversion of the DNA from loosely packed euchromatin to tightly packed heterochromatin.

Chromosomes condense during prophase, align during metaphase, separate during anaphase, and are relocated during telophase.

Example Question #1 : Understanding Mitosis

Which of the following actions occurs during telophase of mitosis?

Possible Answers:

The nucleolus dissolves

Cytokinesis

Nuclear membranes dissolve

Chromosomes line up at the center of the cell

Correct answer:

Cytokinesis

Explanation:

Cytokinesis, the process of the cytosol splitting into two daughter cells, occurs during telophase, the last phase of mitosis. Chromosomes line up at the metaphase plate during metaphase, while the nuclear membranes disappear and the nucleolus dissolve during prophase.

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