Maryland Colony was founded in the 1630s by the Calverts, a prominent family of English Catholics, as a haven for persecuted Catholics from Britain. Massachusetts was the colony founded by and for the Puritans, while Pennsylvania was the colony founded by and for the Quakers (also other religious groups were welcome there). Huguenots started to migrate to North America in large numbers decades after Maryland was founded, and they settled in several colonies. Loyalists only became a distinct, persecuted group once the colonies revolted and gained independence in the late 18th century, and creating a haven for them had nothing to do with the founding of Maryland roughly 150 years earlier.

In the early stages of Revolutionary War, roughly one-third of the country openly supported full rebellion (Patriots), one-thid remained loyal to the Crown (Loyalists), and the final one-third erred on the side of caution. As the war raged on and American success grew more and more likely these numbers shifted dramatically in favor of the Patriot cause. The Loyalists at the beginning of the war were predominantly wealthy, land-owning families and city merchants. They feared that the end of British rule would see the "rebels" free to take their property and disrupt their business. At the end of the war, many of the remaining Loyalists fled North to Canada, or else back to England. 

Shays’ rebellion took place primarily in the state of Massachusetts in 1786 and 1787. It was brought about largely due to economic difficulties and widespread poverty in post-revolution Massachusetts. The rebellion took place during the last years of the Articles of Confederation and helped demonstrate the limitations of the Articles to those at the Constitutional Convention. 

Both sets of colonists were English religious dissenters who wanted to find a place to worship according to their beliefs.  Largely from similar backgrounds, the only real difference between the two groups was their approach to the Church of England.  As separatists, the Plymouth colonists wanted to separate themselves from the Church of England entirely.  The Massachusetts Bay colonists instead wanted to reform the Church of England.

Daniel Boone was the prominent American frontiersman who famously established the first trail into Kentucky. He also founded the first community in Kentucky. Boone became an important figure in popular culture, even within his own lifetime, and soon the legend of Boone eclipsed the reality. Now the history of his life is largely unremembered, but he remains an important figure in American popular culture. 

Anne Hutchinson was an important member of the Antinomian Controversy that swept through the Massachusetts Bay Colony in the 1630s. She was heavily associated with the popular preacher and orator John Cotton, and together they espoused a different interpretation of mankind’s communion with God. Hutchison argued that individuals could commune with God through the Bible and prayer, without the assistance of the clergy. She called this a “covenant of grace”, as opposed to the practices of the clergy, which she called a “covenant of works”. Due to her popularity, she threatened the religious experiment of the Pilgrims and was tried and exiled. She is credited by many historians with helping advance the cause of religious freedom in early colonial America.