Human Anatomy and Physiology : Human Anatomy and Physiology

Study concepts, example questions & explanations for Human Anatomy and Physiology

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Example Questions

Example Question #1441 : Human Anatomy And Physiology

Which nerve is implicated in tarsal tunnel syndrome?

Possible Answers:

Saphenous nerve

Tibial nerve

Deep fibular nerve

Radial nerve

Superficial fibular nerve

Correct answer:

Tibial nerve

Explanation:

Tarsal tunnel syndrome occurs when the tibial nerve is compressed against the flexor retinaculum of the foot and or portions of the talus and calcaneus, as these three structures comprise the tarsal tunnel. Typically, patients with tarsal tunnel syndrome will report numbness, pain, and/or a tingling sensation radiating to the hallux.

Example Question #1442 : Human Anatomy And Physiology

Which nerve is most commonly injured with shoulder dislocations?

Possible Answers:

Radial nerve

Axillary nerve

Long thoracic nerve

Sciatic nerve 

Accessory nerve (CN XI)

Correct answer:

Axillary nerve

Explanation:

The axillary nerve is most commonly injured in shoulder dislocations. The radial nerve is more commonly injured in humerus fractures, the long thoracic nerve is more commonly injured with traction injuries, the accessory nerve is more commonly injured iatrogenically (during surgery), and the sciatic nerve is more commonly injured as a result of vertebral misalignment.

Example Question #1443 : Human Anatomy And Physiology

A patient with a Brown-Séquard type of injury would present with which of the following deficits?

Possible Answers:

Hearing loss

Contralateral deficits in proprioception and vibration sense

Ipsilateral deficits in pain and temperature sensation

Difficulty controlling eye movements

Ipsilateral motor deficits

Correct answer:

Ipsilateral motor deficits

Explanation:

A Brown-Séquard lesion affects half of the spinal cord. Because the spinothalamic tracts decussate at or near the vertebral level they provide sensation too, injury to them would cause contralateral deficits in pain and temperature sensation. By the same principle, the dorsal column medial lemniscus does not decussate until it reaches the medulla, so injury to this tract would cause ipsilateral loss of proprioception and vibration sense. Eye movements and hearing are controlled by cranial nerves, so a spinal cord lesion would not affect them. This leaves ipsilateral motor loss as the correct choice.

Example Question #1444 : Human Anatomy And Physiology

Which nerve is likely injured if it is observed that the scapula is "winged?"

Possible Answers:

Brachial plexus

Long thoracic nerve 

Axillary nerve

Median nerve

Thoracodorsal nerve

Correct answer:

Long thoracic nerve 

Explanation:

The long thoracic nerve (C5-C7) innervates the serratus anterior, which connects the scapula to the thorcaic cage. It is also used for abduction above the horizontal position. During a mastectomy this nerve can be injured leading to a "winged" scapula. A winged scapula is a condition in which the shoulder blade protrudes from a person's back in an abnormal position leading to limited functional activity in the adjacent upper extremity.

Example Question #1445 : Human Anatomy And Physiology

Werdnig-Hoffmann disease is synonymous with which type of Spinal Muscular Atrophy (SMA)?

Possible Answers:

Type III

Type IV

Type V

Type II

Type I

Correct answer:

Type I

Explanation:

SMA involves atrophy of skeletal muscles. Werdnig-Hoffmann disease is synonymous with SMA type I, which involves severe, early onset (first few months of birth) SMA. Dubowitz disease is synonymous with SMA type II (intermediate), which involves onset at around 6-18 months age. Kugelberg-Welander disease, also known as juvenile SMA, is synonymous with SMA type III, and involves the affected individual being able to walk without support at some time, but the probable loss of this ability later in life. SMA type IV does not have an associated eponym, and there is no SMA type V.

Example Question #68 : Injuries And Disorders

What disease is caused by de-myelination of neurons? 

Possible Answers:

Multiple sclerosis 

Muscular dystrophy 

Meningitis 

Dementia 

Alzheimer's disease 

Correct answer:

Multiple sclerosis 

Explanation:

The destruction of myelin sheath is very common in diseases such as multiple sclerosis. It is believed to be an autoimmune disease in which the body destroys the myelin sheath. Other diseases that may result from demyelination are myasthenia gravis and Tay-Sachs disease. Dementia is a symptom of neurodegenerative diseases such as Alzheimer's disease, which is categorized by the presence of neurofibrillary tangles and beta-amyloid plaques in the brain. Meningitis is the inflammation of the meninges. This disease can be caused by several infectious agents such as viruses and/or bacteria. Muscular dystrophy is a genetic disorder in which the dystrophin gene is mutated, disrupting the physical structure of muscles, causing skeletal muscular weakness and death of the muscle cells. 

Example Question #51 : Nervous System

Clinical anxiety and some cases of epilepsy are conditions that involve which neurotransmitter? 

Possible Answers:

Serotonin

Acetylcholine 

Substance P 

GABA

Dopamine

Correct answer:

GABA

Explanation:

GABA is an inhibitory neuron in the brain. When GABA levels are low, the result may be overstimulation of neurons in the brain, which can lead to epileptic seizures or development of clinical anxiety. Dopamine is a neurotransmitter that plays a role in the pleasure-reward system and is linked to schizophrenia and Parkinson's disease. Serotonin is  involved in regulating sensory perception, and onset of sleep and control of mood and emotions. Clinically, serotonin has been implicated in depression and impulsive behavior. Acetylcholine is the neurotransmitter used at the neuromuscular junction. Substance P is a non-opiod neuroactive peptide that is found in the pain pathway in the spinal cord. 

Example Question #52 : Nervous System

Schizophrenia is a condition characterized by marked disturbances in emotional responses, social behavior, and thinking.

Schizophrenia is a condition that involves which neurotransmitter? 

Possible Answers:

Dopamine

Acetylcholine 

Substance P 

Serotonin

GABA

Correct answer:

Dopamine

Explanation:

Schizophrenia is thought to be caused by excessive dopamine release or an abnormal sensitivity to dopamine. Therapeutic drugs for schizophrenia either reduce the secretion of dopamine or bind to dopamine receptors so dopamine is unable to bind. GABA is an inhibitory neuron in the brain. When GABA levels are low, the result may be overstimulation of neurons in the brain, which can lead to epileptic seizures or development of clinical anxiety. Serotonin is involved in regulating sensory perception, and onset of sleep and control of mood and emotions. Clinically, serotonin has been implicated in depression and impulsive behavior. Acetylcholine is the neurotransmitter used at the neuromuscular junction. Substance P is a non-opiod neuroactive peptide that is found in the pain pathway in the spinal cord. 

Example Question #53 : Nervous System

A tremor at rest (which disappears during voluntary movement) and degeneration of dopaminergic neurons are characteristic of what condition? 

Possible Answers:

Parkinson's disease 

Huntington's disease

Grave's disease 

Alzheimer's disease

Meningitis 

Correct answer:

Parkinson's disease 

Explanation:

Parkinson's disease is a disorder of the basal ganglia, which plays a dominant role in movement. Those with Parkinson's will develop a tremor at rest, an increase in rigidity, and slowness in carrying out movements. The neurotransmitter dopamine plays an important role in the development of the disease and the degeneration of dopaminergic fibers occurs in Parkinson's disease. Huntington's Disease is characterized by hyperactivity (rather than a decrease, which is found in Parkinson's disease. GABAergic neurons may be affected during the early stages of the disease, causing over activity. Alzheimer's disease is a neurodegenerative disease that involves memory loss. Meningitis is an infection that causes inflammation of the meninges of the brain. Grave's disease is an autoimmune condition that is characterized by an overproduction of thyroid hormones. 

Example Question #54 : Nervous System

Myasthenia Gravis is an autoimmune condition which is characterized by rapid fatigue and weakness of muscles under voluntary control. 

Myasthenia Gravis is an autoimmune disease in which the body develops antibodies against which of the following neurotransmitters? 

Possible Answers:

Serotonin 

GABA 

Epinephrine

Acetylcholine 

Dopamine

Correct answer:

Acetylcholine 

Explanation:

Acetylcholine is the neurotransmitter used at the neuromuscular junction. The antibodies produced against acetylcholine receptors at the neuromuscular junction prevent synaptic transmission, causing the muscle weakness and fatigue characterized by Myasthenia Gravis. Epinephrine(also known as adrenaline) is a monoamine that plays an important role in the sympathetic nervous system. GABA is the main inhibitory neurotransmitter in the brain. Dopamine is neurotransmitter that plays an important role in the body's pleasure and reward system. It is characterized as a catecholamine. Serotonin is a monoamine neurotransmitter that acts throughout the body and plays a role in depression and happiness. 

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