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Example Questions
Example Question #212 : Fundamental Macromolecules And Concepts
For this reaction, at given reaction conditions.
Which of the following statements concerning the reaction is true?
Entropy increases as the reaction proceeds to the left
The mixture contains more reactants than products
The mixture contains an equal amount of reactants and products
The mixture contains more products than reactants
More than one of these
The mixture contains more products than reactants
Because for the reaction is negative, it is spontaneous and proceeds favorably to the right. Equilibrium does not occur when the concentrations of reactants and products are equal; it occurs when the rates of forward and reverse reactions are equal. At equilibrium thus there is no net change in the concentration of either the reactants or the products.
Example Question #1 : Biological Energetics
Regarding formation of double stranded DNA from two complementary single strands, which of the following is true?
The formation of dsDNA is entropically and enthalpically favorable.
The formation of dsDNA is entropically favorable, but is enthapically unfavorable.
The formation of dsDNA is entropically unfavorable, but is enthalpically favorable.
None of these
The formation of dsDNA is entropically and enthalpically unfavorable.
The formation of dsDNA is entropically unfavorable, but is enthalpically favorable.
If two complementary single strands of DNA are put into a solution, they will spontaneously form dsDNA. This process results in a loss of heat from the system - demonstrating that it is an enthalpically favorable process. However, it is entropically unfavorable given the formation of a more ordered structure.
Example Question #2 : Biological Energetics
A person just eats a very large meal filled with starches and sugars. What is expected to happen to their insulin to glucagon ratio as a result? Assume the person is not diabetic.
Insulin will levels will increase and glucagon levels will drop to zero
Glucagon will increase relative to insulin
The ratio will remain more or less constant
Glucagon will levels will increase and insulin levels will drop to zero
Insulin will increase relative to glucagon
Insulin will increase relative to glucagon
Insulin is produced by pancreatic beta cells in response to a rise in blood sugar, which occurs after eating a meal rich in carbohydrates (sugars and starches). It causes other cells of the body to take up the blood sugar (primarily glucose) and use it for energy production, and it prompts the liver to store excess glucose as glycogen. Glucagon is produced when blood sugar is too low, and it blocks glycolysis and prompts liver cells to convert stored glycogen back to glucose and release it and also produce glucose through gluconeogenesis. This is always determined by the ratio of the levels of two hormones - if there is far more insulin than glucagon, its physiological effects will dominate. There is never absolutely zero of either hormone unless the individual is diabetic to such a degree that their cells cannot produce insulin.
Example Question #51 : Homeostasis And The Biological Environment
Under what conditions will a reaction with a positive change in entropy and a positive change in enthalpy take place spontaneously?
When temperature is very high
This reaction will always take place spontaneously
When temperature is very low
This reaction will never take place spontaneously
When pressure is low
When temperature is very high
A negative change in Gibbs free energy means that a reaction will take place spontaneously. By using the equation:
We can see that if both entropy and enthalpy are positive, will only be negative when is sufficiently high.
Example Question #605 : Biochemistry
What is reaction coupling?
Pairing two reactions together in order to alter their chemical equilibriums
Driving an unfavorable reaction forward by pairing it with a very favorable reaction
Combining two reactions in order to double the amount of product that will be created
Stopping a favorable reaction from occurring by pairing it with an unfavorable reaction
Pairing two unfavorable reactions together so that they both become favorable
Driving an unfavorable reaction forward by pairing it with a very favorable reaction
Reaction coupling is the pairing of one unfavorable reaction to another reaction that is favorable. The energetics of the favorable reaction drive the unfavorable one forward.
Example Question #606 : Biochemistry
Which of the following is true of a reaction that has reached equilibrium?
The rate of the reaction is at its maximum
There is no net movement between the products and reactants
The reaction quotient (Q) is greater than the equilibrium constant (Keq)
The reaction quotient (Q) is less than the equilibrium constant (Keq)
There is no movement at all between products and reactants
There is no net movement between the products and reactants
It is a common misconception that at chemical equilibrium, movement between the product and reactant sides of the equation has stopped. In reality, reactants and products are still converting back and forth to one another, however there is no longer any net movement from one side of the equation to the other. Also, Q=Keq at equilibrium.
Example Question #11 : Biological Energetics
Some reactions that occur within cells have a large, positive standard free energy change. How is it that these reactions are able to occur, given that they are so energetically unfavorable?
The conditions found within cells are different than standard conditions
These reactions are coupled with highly exergonic reactions
Oftentimes, the product of an endergonic reaction is readily used up in another reaction, thus keeping the concentration of product in the endergonic reaction low
All of these are true
All of these are true
All of the answer choices given in this question are true statements, and they are all reasons why endergonic reactions can occur within living things.
Oftentimes, reactions that require a large input of energy are thermodynamically coupled to the hydrolysis of ATP, the energy currency of the cell. As a result, ATP is able to provide the fuel, so to speak, for powering the reaction.
Also, it's important to note that standard free energy changes are much different than the free energy changes that occur under physiological conditions. Standard state assumes that all reactants and all products of a reaction start out at a concentration of , but this concentration is absurdly high for just about any compound found within cells.
Lastly, the products of some endergonic reactions are often used up quite readily. As a result of this, the concentration of product is kept at a low level, which means that the reactions becomes favored toward making more product.
Example Question #52 : Homeostasis And The Biological Environment
Why is polymerization of nucleoside triphosphates thermodynamically favorable?
During the polymerization, ATP is released from the nucleoside when the base is attached which, because it is creating energy, is favorable.
The polymerization is coupled to ATP hydrolysis.
The polymerization of nucleoside triphosphates is not thermodynamically favorable, but it is kinetically favorable.
During the polymerization, one phosphate group is released and this drives the reaction forward.
During the polymerization, pyrophosphate is released and hydrolyzed driving the reaction forward.
During the polymerization, pyrophosphate is released and hydrolyzed driving the reaction forward.
A nucleoside triphosphate - as its name suggests - is a DNA base with three phosphate groups. During polymerization, these base groups will be continuously connected to each other in order to form a DNA strand. This is thermodynamically favorable because during the polymerization, two of the three phosphate groups on the nucleoside triphosphate will detach as a pyrophosphate. This will then be hydrolyzed which is extremely thermodynamically favorable. And so, the polymerization itself is considered to be thermodynamically favorable.
Example Question #53 : Homeostasis And The Biological Environment
Which of the following is false about the hemoglobin R state?
It is more stable in the presence of oxygen
The heme group is planar
It has a higher affinity for oxygen
It is more stable in the absence of oxygen
It is triggered by oxygen binding
It is more stable in the absence of oxygen
The R (relaxed) state hemoglobin is triggered by hemoglobin binding to oxygen. The heme group in R state hemoglobin is perfectly planar. By nature, R state hemoglobin is stabilized in the presence of oxygen, not in the absence of oxygen.
Example Question #611 : Biochemistry
Suppose that the enthalpy change for a given biochemical reaction is zero. What is the change in standard free energy for this reaction?
To answer this question, it's important to know how the standard free energy change of a reaction is related to other various parameters of the reaction.
The standard free energy change of a reaction can be presented in different expressions.
For the purposes of this question, the bottom expression is the one we need. If we set the change in standard enthalpy term equal to zero, we can solve for our answer.
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