The left ventricle is the most commonly enlarged heart structure seen in chronic hypertension. The left ventricle must overcome the afterload of the arterial system by becoming hypertrophied. As a result, the heart gets remodeled to overcome the systemic high blood pressures. The left ventricle directly pumps blood from the heart to the systemic circuit.

T-cell maturation occurs in the thymus, a small organ located in the upper part of the mediastinum, between the heart and the sternum. Mature T cells then may either circulate in the lymph or blood or reside in lymph nodes. The spleen is not a site of T cell maturation, though it does have other important immune functions, such as the production of antibodies and the removal of antibody-coated pathogens. The cisterna chyli is a part of the lymphatic system that is involved in lipid digestion.

Dietary fat is absorbed via lacteals, small lymph vessels contained within the body of the intestinal villi. Microvilli, tiny projections covering the surface of the villi, help with the absorption of minerals, vitamins, and other micronutrients. The cisterna chyli is a dilated pouch at the lower end of the thoracic duct that serves as a collection point for fatty chyle from the intestinal lacteals.

The lymphatic system has several roles in the body, including drainage of interstitial fluid from tissues, transportation and activation of lymphocytes, and absorption and transportation of dietary fats. Red blood cells, however, are unable to enter lymph vessels, and so the lymphatic system does not participate in any type of gas exchange.

Each heme group in hemoglobin encloses a single iron atom in the center of a protoporphyrin, a tetrapyrrol composed of four pyrrole rings linked together by four methyl groups, two vinyl groups, a methane bridge, and two propinoic acid side chains.

The average lifespan of a red blood cell is 4 months, after which it is phagocytosed by macrophages the spleen, liver, or lymph nodes. White blood cells, on the other hand, live for only about 3-4 days.

The casting of new red blood cells is stimulated by the hormone erythropoietin (EPO), released from the kidneys. Recall that all blood cells are made in the bone marrow. This hormone may increase as much as 1000 fold in times of oxidative stress.

Thyroxine is T4, the most biologically active form of thyroid hormone. Vasopressin, or anti-diuretic hormone, is part of the body's fluid-balance system. Luteinizng hormone is a hormone of the reproductive tract: in females it triggers ovulation, while in males it stimulates Leydig cells to produce testosterone.

Erythropoietin is produced by the peritubular interstitial cells of the kidney. These cells are very sensitive to tissue oxygen pressure. When oxygen demand increases, erythropoietin is released, stimulating the casting (hematopoiesis) of new red blood cells in bone marrow. 

Supraoptic and paraventricular cells of the hypothalamus are the site of vasopressin (antidiuretic hormone) production. Lactotroph cells in the pituitary gland are responsible for the production of prolactin. Zona fasciculata cells of the adrenal glands produce cortisol.

Neutrophils are the most common type of white blood cell, making up 55-70% of the total white blood cell population in the average blood sample.