MCAT Biology : Reactions
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Example Questions
Example Question #3 : Other Reaction Mechanisms
The enzyme glucose-6-phosphatase plays the most important role in which tissue/organ?
Muscle tissue
Liver
Adipose tissue
Brain
Liver
Glucose-6-phosphatase is responsible for removing the phosphate group from glucose-6-phosphate. The result is free glucose, which can be released into the blood. This process takes place at the end of either glycogenolysis or gluconeogenesis, both processes that are most prominent in the liver due to its large stores of glycogen.
Example Question #4 : Other Reaction Mechanisms
Which of the following statements is false regarding enzyme function?
All of these are true
Enzymes are a type of catalyst
Enzymes do not affect the thermodynamics of a reaction
Enzymes are not used up during the reaction
Enzymes increase the activation energy
Enzymes increase the activation energy
Enzymes function as a biological catalysts by lowering reactions' activation energies. They are not used up in the reaction mechanism, nor do they affect the thermodynamics of the reaction. They only affect the reaction kinetics.
Example Question #3 : Other Reaction Mechanisms
The cellular membrane is a very important structure. The lipid bilayer is both hydrophilic and hydrophobic. The hydrophilic layer faces the extracellular fluid and the cytosol of the cell. The hydrophobic portion of the lipid bilayer stays in between the hydrophobic regions like a sandwich. This bilayer separation allows for communication, protection, and homeostasis.
One of the most utilized signaling transduction pathways is the G protein-coupled receptor pathway. The hydrophobic and hydrophilic properties of the cellular membrane allows for the peptide and other hydrophilic hormones to bind to the receptor on the cellular surface but to not enter the cell. This regulation allows for activation despite the hormone’s short half-life. On the other hand, hydrophobic hormones must have longer half-lives to allow for these ligands to cross the lipid bilayer, travel through the cell’s cytosol and eventually reach the nucleus.
Cholesterol allows the lipid bilayer to maintain its fluidity despite the fluctuation in the body’s temperature due to events such as increasing metabolism. Cholesterol binds to the hydrophobic tails of the lipid bilayer. When the temperature is low, the cholesterol molecules prevent the hydrophobic tails from compacting and solidifying. When the temperature is high, the hydrophobic tails will be excited and will move excessively. This excess movement will bring instability to the bilayer. Cholesterol will prevent excessive movement.
Epinephrine binds to its receptor on the surface of the cell. Molecule A does bind to the same receptor but is found to bind a different part of the receptor molecule than does epinephrine, causing the receptor to undergo a confirmation change and no longer fits with its associated ligand. What type of regulation is this?
Noncompetitive inhibition
Partial inhibition
Direct inhibition
Competitive inhibition
None of these
Noncompetitive inhibition
According to the question, molecule A acts on a different site to inhibit epinephrine's receptor. This is an example of a noncompetitive inhibitor.
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