All MCAT Biology Resources
Example Questions
Example Question #21 : Mcat Biological Sciences
Chromatography involves the separation of a mixture by allowing a mobile phase to travel along a stationary phase. In thin layer chromatography (TLC), a liquid solution is able to travel along a stationary plate. The distance that a particular compound travels compared to another compound can be determined by comparing the Rf factors for each compound. The Rf factor is determined by dividing the compound's distance by the total distance of the solvent.
Another type of chromatography commonly used is gas chromatography. How is this type of chromatography different from thin layer chromatography?
The stationary and mobile phases are in different phases
Only thin layer chromatography can determine the purity of a solution
In gas chromatography, nonpolar compounds move a shorter distance than polar compounds
Gas chromatography takes advantage of the compounds' different melting points
The stationary and mobile phases are in different phases
Gas chromatography and thin layer chromatography differ by the phases of both the mobile and stationary phases. In gas chromatography, the mobile phase is a gas and the stationary phase is a liquid. In thin layer chromatography, the mobile phase is a liquid and the stationary phase is a solid.
Example Question #22 : Mcat Biological Sciences
A chemist carries out the synthetic scheme shown below. Unfortunately, the first two reactions are incomplete, and a mixture of compounds A, B, and C is obtained after the second step. The chemist purifies this mixture by normal phase chromatography, using silica gel as a stationary phase and a 10:1 hexanes-diethyl ether (v:v) solution as an eluent. In what order would compounds A, B, and C elute off the column?
For each choice, the first compound to elute is listed first.
C, B, A
B, C, A
A, C, B
B, A, C
C, A, B
C, A, B
In the normal phase chromatography system described, the most nonpolar compound would elute first and the most polar compound would elute last. The silica stationary phase will interact with more polar molecules, while the hexane mobile phase will carry nonpolar molecules. This would slow the progress of polar molecules as they bond to the silica, and enhance the progress of nonpolar molecules as they interact with the mobile phase.
Compound C is the most nonpolar compound because it contains only hydrogen and carbon. Compounds A and B are more polar because of the presence of oxygen, and hence the presence of polarized carbon-oxygen bonds. The alcohol group of compound B makes this compound the most polar of the three molecules by virtue of hydrogen bonding capabilities as well as the carbon-oxygen dipole. Compound B would thus elute last.
Example Question #22 : Organic Chemistry, Biochemistry, And Metabolism
Chromatography involves the separation of a mixture by allowing a mobile phase to travel along a stationary phase. In thin layer chromatography (TLC), a liquid solution is able to travel along a stationary plate. The distance that a particular compound travels compared to another compound can be determined by comparing the Rf factors for each compound. The Rf factor is determined by dividing the compound's distance by the total distance of the solvent.
Consider a mystery compound with an Rf factor of 0.6. Which of the following statements would you predict to be accurate?
A more nonpolar compound can have twice the Rf factor of the mystery compound
A more polar compound would have a lower Rf factor than the mystery compound
A compound with a higher molecular weight will travel a farther distance than the mystery compound
A more nonpolar compound can travel twice the distance of the mystery compound
A more polar compound would have a lower Rf factor than the mystery compound
The Rf factor is a ratio of the compound's travel distance compared to the solvent's travel distance; this value will always be between 0 and 1. As a result, a nonpolar compound would not be able to travel twice the distance or have twice the Rf factor as the mystery compound. This would result in a value of 1.2.
The only thing we can predict confidently is that a more polar compound would travel a shorter distance than the mystery compound, which result in a lower Rf factor.
Example Question #1 : Biology
To form a female zygote, the sperm cell must contribute which chromosome(s)?
An X-chromosome
Two X-chromosomes
Both an X- and a Y-chromosome
A Y-chromosome
Two Y-chromosomes
An X-chromosome
The necessary genotype for a female zygote is XX.
The mother will share this XX genotype (since she is also female) and will contribute one X-chromosome. The father, however, will be male and have the genotype XY. This means he has a 50% chance of passing on an X-chromosome and a 50% chance of passing on a Y-chromosome. If the zygote inherits a Y-chromosome from the father's sperm, then the offspring will be male. If the zygote inherits an X-chromosome from the father's sperm, then the resulting genotype will be XX and the offspring will be female.
Example Question #1 : Embryogenesis
What is a totipotent cell?
A cell that has the ability to form a complete organism through embryogenesis
A cell that has the ability to differentiate into any type of tissue if exposed to the appropriate chemical signals
Stem cells from adult tissues
A cell that has the ability to differentiate into a limited number of tissue types if exposed to the appropriate chemical signals
Stem cells from the inner cell mass
A cell that has the ability to form a complete organism through embryogenesis
Totipotent cells have the ability to propogate and differentiate into any cell types, including the trophoblast. They are different from stem cells, which could be considered multipotent (able to differentiate into multiple tissue types) or pleuripotent (able to differentiate into any major tissue type, but cannot create trophoblast). The only truly totipotent cells are the first two blastomeres.
Example Question #1 : Systems Biology And Tissue Types
What is the "common dogma"?
None of the other answers
Cells lose genetic material over time, becoming less totipotent
All cells come from other cells
Most cells in the body contain a complete genome, despite the fact that most of the genes in the genome are not necessary for each cell's specific function
All organisms are made of cells
Most cells in the body contain a complete genome, despite the fact that most of the genes in the genome are not necessary for each cell's specific function
Most cells contain a complete genome, but not all genes are activated in each cell. Activation of particular genes produces appropriate protein function.
Example Question #1 : Reproductive System And Development
Differentiation of the endoderm in a developing human embryo will eventually give the human the ability to __________.
think
produce urine
move
circulate blood
breathe
breathe
The endoderm develops into a number of internal organs, including the lung, which are vital for breathing.
The kidneys (urine production), muscles (movement), and blood vessels (blood circulation) develop from the mesoderm. The brain (thought) develops from the ectoderm.
Example Question #1 : Biology
A new medication has been created that is very effective at treating brain tumors; however, the medication has a short half-life once inside the body. If the medication travels through the blood stream, which method of administration would give the medication the most time to affect a tumor in the brain? (Assume an equal dosage of the medicine is used for each potential method.)
Inhalation
Subcutaneous Injection
Intravenous Injection (Jugular Vein)
Sublingual
Inhalation
This question is targeting your knowledge of the circulatory system. Since the medication has a short half-life, it is necessary that it be carried by the patient's blood stream to the tumor as quickly as possible. Blood travels through the right side of the heart, to the lungs, through the left side of the heart, then to the body. Therefore, inhalation of a chemical would require the least amount of traveling (Lungs, Left Atrium, Left Ventricle, Body). Each other method of administration, including IV, would require more time to travel to the brain. For example, for the IV answer choice, the pathway would be Vein, Right Atrium, Right Ventricle, Lungs, Left Atrium, Left Ventricle, Body.
Example Question #1 : Other Biology Concepts
Thermoregulation of the human body is controlled by a __________.
negative feedback mechanism
positive feedback mechanism
None of these answers
set of hormones
biological rhythm
negative feedback mechanism
Like many biological functions, thermoregulation is controlled by a negative feedback system. This is because the response is the opposite of the input: a hot environment triggers cooling, while a cool environment triggers heating. A positive feedback system would intensify a response in the same direction as the input. If a positive feedback mechanisms were true of regulating body temperature, cold weather would trigger sweating and dilation of blood vessels. The result would be that you would get even more cold, which would not be good for maintaining homeostasis. Hormones do help regulate many body functions, but they are not the best description of how body temperature is controlled.
Example Question #2 : Other Biology Concepts
Which of the following accurately describes the body of a fresh water fish immediately following its transfer to a salt-water aquarium?
Hypertonic
Hyperosmotic
Hypotonic
Isotonic
Hypotonic
In its home environment, the fresh water fish will be in equilibrium with its surroundings. As such, it will essentially be isotonic with a fresh water solution. This represents a relatively low solute concentration in the fish's body.
When we transfer this fish to a medium that is more densely concentrated with solute molecules, the fresh-water fish will be hypotonic in relation to the external medium. The salt in the surrounding water will cause the external environment to be more concentrated than the body of the fish. As a result, the fish will quickly become dehydrated as water exits its body.
Hypertonic and hyperosmotic are synonyms, which both refer to greater concentrations than the surroundings (opposite the scenario described).
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