All GRE Subject Test: Biochemistry, Cell, and Molecular Biology Resources
Example Questions
Example Question #5 : Enzyme Regulation
How does a noncomeptitive inhibitor affect an enzyme?
Raises the Michaelis constant of the enzyme
Lowers the maximum rate of the enzymatic reaction
Raises the maximum rate of the enzymatic reaction
Lowers the Michaelis constant of the enzyme
Lowers the maximum rate of the enzymatic reaction
A noncompetitive inhibitor acts to decrease how fast the enzyme can act on substrates. It accomplishes this by lowering the maximum rate at which it can create products. Noncompetitive inhibitors do not alter the enzyme's Michaelis constant.
Example Question #6 : Enzyme Regulation
How is pepsinogen activated in the stomach?
It is phosphorylated by another enzyme
It is activated by the temperature change in the stomach lumen
Cofactors bind to the enzyme, increasing its efficiency
A portion is cleaved, activating the enzyme
A portion is cleaved, activating the enzyme
Once in the stomach lumen, pepsinogen finds itself in a very acidic environment. The acidic environment cleaves an amino acid sequence from pepsinogen, turning it into the active enzyme pepsin. This type of activation causes pepsin to only activate in the stomach lumen where it is needed.