NCLEX : General Biology

Study concepts, example questions & explanations for NCLEX

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Example Questions

Example Question #53 : Musculoskeletal System And Anatomy

All of the following features are unique to cardiac muscle cells except:

Possible Answers:

They are linked together via intercalated discs

They are non-striated

There are gap junctions between cells

They form branching chains

Correct answer:

They are non-striated

Explanation:

Cardiac muscle cells are striated, branching cells that are linked by structures called intercalated discs. These discs are composed of gap junctions, which allow the free passage of electrical signaling between heart cells, and very strong attachment points called desmosomes.

Example Question #241 : General Biology

A nurse is examining a patient who has muscle pain and fatigue after working out. He determines that the patient has muscle strain. This is generally caused by which of the following?

Possible Answers:

There is damage to ligamentous attachments

Hypertrophy is causing swelling of the muscle fiber

Excessive contraction causes tetany in the muscle body

The actin and myosin filaments have been pulled past their ability to overlap

Correct answer:

The actin and myosin filaments have been pulled past their ability to overlap

Explanation:

Muscle strain is often caused by over stretching, during which actin and myosin heads are pulled to the extent that they are no longer overlapping, possibly to the point of causing tears in muscle tissue. Tears in ligaments are sprains, rather than strains.

Example Question #7 : Muscle Physiology

Which is the only muscle type that is non-striated?

Possible Answers:

Smooth muscle

Voluntary

Cardiac muscle

Skeletal muscle

Correct answer:

Smooth muscle

Explanation:

The only type of muscle that is not striated is smooth muscle. Smooth muscle does not use sarcomeres for contraction - rather, each muscle cell is a spindle that is covered in a mesh of contractile fibrils. These fibrils contract in unison when calcium enters the cell.

Example Question #62 : Musculoskeletal System And Anatomy

Which of the following is the smallest unit of contractile tissue in cardiac and skeletal muscle cells?

Possible Answers:

Myosin filament

The sarcomere

Actin filaments

The myofibril

Correct answer:

The sarcomere

Explanation:

The smallest contractile unit in muscle tissue is the sarcomere. Myofibrils are made up of many sarcomeres attached end-to-end at a series of dark lines (hence the term "striated") called Z lines. Each sarcomere contains actin and myosin filaments, which pull together during contraction to shorten the sarcomere.

Example Question #11 : Muscle Physiology

The sliding filament theory of muscle contraction involves the __________ attaching to __________ and then pulling during the power stroke. 

Possible Answers:

actin head . . . myosin

myosin head . . . actin

troponin . . . actin

myosin . . . tropomyosin

Correct answer:

myosin head . . . actin

Explanation:

The sliding filament theory of muscle contraction involves the myosin head attaching to actin and then pulling during the power stroke. Troponin is a protein attached to tropomyosin, a thin strand wrapping around the actin filament. When calcium enters the cell, troponin moves toward it, pulling the tropomyosin strand away from actin binding sites and allowing the myosin head to bind. 

Example Question #61 : Musculoskeletal System And Anatomy

Which of the following molecules binds to troponin during muscle contraction, triggering tropomyosin to move away from the actin binding sites and allowing the myosin head to form a cross bridge?

Possible Answers:

Sodium

Calcium

ATP

ADP

Correct answer:

Calcium

Explanation:

During a muscle cell action potential, calcium enters the cell via t-tubules, which are specialized invaginations of the sarcoplasmic reticulum. Calcium binds with troponin, which pulls the tropomyosin strand away from actin binding sites and allows myosin heads to bind. Neither sodium nor potassium bind to troponin, and ATP and ADP both bind to myosin, rather than troponin.

Example Question #62 : Musculoskeletal System And Anatomy

Which of the following is the name of the modified endoplasmic reticulum found in muscle cells?

Possible Answers:

The sarcomere

The myoplasmic reticulum

The sarcoplasmic reticulum

The t-tubule

Correct answer:

The sarcoplasmic reticulum

Explanation:

Muscle cells have a specialized endoplasmic reticulum called the sarcoplasmic reticulum. The sarcoplasmic reticulum regulates the calcium ion concentration in the cytoplasm of striated muscle cells, and so plays a significant role in muscle contraction and relaxation. The T-tubule is a specialized invagination of the sarcoplasmic reticulum, and the sarcomere is the single contractile unit of a muscle fibril. There is no muscle structure called the mycoplasmic reticulum.

Example Question #1 : Joints

The articulation between the intervertebral disc is what type of joint?

Possible Answers:

Synarthrotic

Synovial

Cartilaginous

Diarthrotic

Correct answer:

Cartilaginous

Explanation:

The intervertebral disc articulate with the vertebrae via cartilaginous symphysis joints. These joints are amphiarthrotic, meaning that they allow for slight mobility. 

Synovial joints are all diarthrotic and characterized by a flexible joint capsule filled with synovial fluid. Synarthrotic joints have no movement - examples include the skull bones and the joints of the teeth to the jaw.

Example Question #2 : Joints

The head of the femur articulates with what structure of the hip joint?

Possible Answers:

The glenoid fossa

The obturator foramen

The patella

The acetabulum 

Correct answer:

The acetabulum 

Explanation:

The head of the femur articulates with the acetabulum, a concave surface on the pelvis formed by the union of three bones: the ilium, the ischium, and the pubis. 

The obturator foramen is a large opening in the pelvis formed by the pubis and the ischium bilaterally. It does not form any joints but rather allows the passage of the obturator artery, nerve, and vein.

The glenoid fossa is the surface onto which the head of the humerus articulates in the shoulder, and the patella is a part of the knee.

Example Question #1 : Joints

Which of the following structures is a type of synovial fluid sac between bones and overlying tissues?

Possible Answers:

Bursa

Capsule

Ligament

Tendon

Correct answer:

Bursa

Explanation:

Bursae are synovial fluid sac between bones and overlying tissues. They provide a cushion between the bone and tendons or musculature around them, allowing for reduced friction and painless movement.

A tendon is a connective tissue point of attachment of muscle to bone, while a ligament is a connective tissue attachment from bone to bone. A capsule is a fibrous, fluid filled structure surrounding a synovial joint.  

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