All MCAT Biology Resources
Example Questions
Example Question #291 : Biology
The diaphysis is able to grow in length because of thin layers of cartilage cells located in which of the following regions?
Medullary cavity
Marrow
Haversian canal
Epiphyseal plate
Periosteum
Epiphyseal plate
Thin layers of cartilage cells in the epiphyseal plate enable the diaphysis (bone shaft) to grow in length. The epiphyseal line forms when growth stops and ossification occurs, permanently fusing the diaphysis and epiphysis.
The periosteum is a tough connective tissue sheath that covers the outer surface of bones. The medullary cavity is a hollow cylinder inside the diaphysis. The medullary cavity contains bone marrow, which contains blood cells in different stages of development. The Haversian canals perforate bony structure and contain blood vessels, lymph vessels, and nerves.
Example Question #1 : Bone
What type of bone cell is responsible for resorbing bone tissue?
Osteocytes
Lacunae
Cartilage
Osteoblasts
Osteoclasts
Osteoclasts
Osteoclasts are bone cells that are responsible for resorbing—or breaking down—bone tissue. Osteoblasts, on the other hand, deposit bone tissue.
Cartilage is not a type of bone cell at all; it is a type of connective tissue consisting of chondrocytes suspended in an avascular matrix. Lacunae are small cavities within the bone matrix that house osteocytes; osteocytes are mature bone cells.
Example Question #2 : Bone
How do bones maintain a functional weight as they grow?
Osteocytes form long fibers around the medullary cavity
Osteoclasts lining the medullary cavity remove interior layers of matrix
Osteocytes create new Haversian systems to limit the bone weight
Osteoblasts secrete acidic compounds, which dissolve some of the adjoining matrix
Osteoblasts creates new lacuna to surround bone cells
Osteoclasts lining the medullary cavity remove interior layers of matrix
Osteoclasts dissolve bony matrix and repatriate calcium as the bone grows. This expands the meduallary cavity and maintains a manageable mass for the bones, while allowing the body to recycle valuable calcium deposits.
Example Question #292 : Biology
Where are osteocytes located?
Beneath the periosteum
The lacunae of Haversian systems
The lining of the medullary cavity
Throughout the hydroxyapatite matrix
Surrounding the growth plates
The lacunae of Haversian systems
Osteoytes, the long-lived star-shaped cells found in established bones, are primarily found within Haversian systems—the target-shaped tubes of bone matrix. They are encased in a bubble of interstitial fluid known as a lacuna.
Example Question #2 : Bone
An adolescent girl is suffering from reduced longitudinal bone growth in her humerus. Which of the following bone regions should be examined closely in order to determine the cause of the growth deficiency?
The periosteum
The epiphyseal plate
The diaphysis
Articular cartilage
The epiphyseal plate
Longitudinal bone growth occurs at the epiphyseal plate through the process of endochondral ossification. Cartilage cells undergo rapid mitosis in this region forming the structure that is later replaced by bone tissue.
Example Question #3 : Bone
In childbirth, the child’s skull is flexible due to fontanelles, or soft regions that are composed of connective tissue. Through what process does the connective tissue of the infant’s skull become bone?
Endochondral ossification
Intramembranous ossification
Compact bone resorption
Bony secretion
Intramembranous ossification
Intramembranous ossification is the process in which bones are formed within dermal tissue. This process is responsible for forming the flat bones of the skull, as well as the clavicle. Other bones of the body are formed by the process of endochondral ossification, in which cartilage is replaced by bone tissue.
Example Question #1 : Types Of Bone Cells
__________ function to synthesize bone tissue and __________ function to reabsorb bone tissue.
Osteoblasts . . . osteoblasts
Osteoblasts . . . osteoclasts
Osteoclasts . . . osteoblasts
Osteoclasts . . . osteoclasts
Osteoblasts . . . osteoclasts
Bones consist of two types of cells that regulate bone growth: osteoblasts and osteoclasts. Osteoblasts lay down collagen and other important organic substances that are required to synthesize bone tissue, whereas osteoclasts reabsorb existing bone tissue. The activity of both cells is important for repair, growth, and maintenance of bone tissue.
Note that a third type of cell, osteocytes, is also found in bone, but does not play as much of an active role in maintaining bone structure.
Example Question #1 : Types Of Bone Cells
Several tests reveal that a unknown hormone reverses the effects of parathyroid hormone. What can you conclude about this unknown hormone?
It decreases osteoblast activity and increases blood calcium levels
It decreases osteoblast activity and decreases blood calcium levels
It decreases osteoclast activity and decreases blood calcium levels
It decreases osteoclast activity and increases blood calcium levels
It decreases osteoclast activity and decreases blood calcium levels
The question states that the unknown hormone has the opposite effect of parathyroid hormone. Recall that parathyroid hormone functions to increase blood calcium levels; therefore, this unknown hormone must decrease blood calcium levels.
When blood calcium levels increase due to parathyroid hormone, osteoclasts in bones break down the bone matrix and release the calcium into the blood. This means the activity of the unknown hormone must inhibit the activity of osteoclasts to decrease blood calcium levels. This hormone is most likely released to prevent bone loss.
The unknown hormone in this question would most likely be calcitonin. Calcitonin decreases blood calcium levels and is very important in menopausal and pregnant women who have a higher risk of having excessive bone loss.
Example Question #91 : Musculoskeletal System And Muscle Tissue
A researcher takes a sample of bone tissue and observes a cell under a microscope. He notices that the cell is in the process of breaking down its nuclear membrane. Based on this information, what can the researcher conclude about this cell?
The cell is an osteoclast
The cell can be either an osteoblast or an osteoclast
The cell is an osteoblast
The cell cannot be an osteoblast or an osteoclast
The cell cannot be an osteoblast or an osteoclast
The question states that the cell is breaking down its nuclear membrane. Recall that the nuclear membrane is broken down during prophase of mitosis or prophase I of meiosis; therefore, the cell must be undergoing either mitosis or meiosis. One of the key characteristics of osteoblasts, osteocytes, and osteoclasts is that they do not undergo mitosis. Also, remember that only germ cells undergo meiosis. Since the observed cell is undergoing a division, the researcher can conclude that the cell is not an osteoblast or an osteoclast.
Osteogenic cells, however, can undergo mitosis. Osteogenic cells are cells that differentiate into osteoblasts. Once differentiated, the osteogenic cells can no longer undergo mitosis.
Example Question #4 : Types Of Bone Cells
Which cells are responsible for building bone?
Osteoblasts
Marrow
Osteomites
Myofibrils
Osteoclasts
Osteoblasts
Osteoblasts form bone by crystalizing calcium phosphate around collagen.
Certified Tutor
Certified Tutor