Human Anatomy and Physiology : Gross Anatomy

Study concepts, example questions & explanations for Human Anatomy and Physiology

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Example Questions

Example Question #285 : Organs

Where do B-lymphocytes differentiate and mature in the body?

Possible Answers:

Bone marrow

Lymph nodes

Pancreas

Thymus

Correct answer:

Bone marrow

Explanation:

B-lymphocytes mature in the bone marrow. They can also be created and matured in the liver. Both types of lymphocyte originate from stem cells in the bone marrow, but differ in their site of maturation.

T-lymphocytes mature in the thymus, where they interact with "self antigens." This process ensures that T-lymphocytes do not interact with antigens found in the body. If the immature cell interacts with self antigens, the T-lymphocyte will be destroyed. Mature T-lymphocytes that still react to self antigens can cause allergic reactions and autoimmune disease.

Mature lymphocytes are most commonly found in the lymph nodes, where they screen the plasma and fluids for antigens.

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