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Example Questions
Example Question #1 : Help With Stomach Physiology
Which stomach cell type secretes the that converts pepsinogen to pepsin in the stomach and, secretes intrinsic factor, for vitamin B12 absorption later in the gastrointestinal tract?
Parietal cells
Goblet cells
G-cells
Chief cells
Parietal cells
Goblet cells secrete mucous, which protects the stomach lining. Chief cells secrete pepsinogen, which must be converted to pepsin by acid in order to carry out its function of breaking down proteins. G-cells secrete gastrin, increase secretion from the other cells, and induce muscle contractions. Parietal cells secrete both and intrinsic factor.
Example Question #2 : Help With Stomach Physiology
Which of the following describes venous blood leaving the stomach?
Basic in pH
Basic in pH when food is present, and acidic in pH when food is absent
Acidic in pH
Neutral in pH
Acidic in pH when food is present, and basic in pH when food is absent
Basic in pH
Since the stomach releases ions into the stomach, it releases bicarbonate into its venous supply, which can feed into the pancreas. This allows the pancreas to release the bicarbonate into the lumen to help neutralize the stomach acid. Remember, the venous blood leaving the pancreas is acidic in nature and can help provide the stomach with a supply of ions for its functionality.
Example Question #3 : Help With Stomach Physiology
Which of the following is not a function of hydrochloric acid in the stomach?
It nonspecifically destroys pathogens
It lowers the pH of the stomach, bringing it to pepsin's optimum
It denatures peptide bonds in the protein
It helps activate pepsinogen into the enzyme pepsin
It denatures the protein by breaking down the protein's quaternary and tertiary structure
It denatures peptide bonds in the protein
Hydrochloric acid does not break peptide bonds. Instead, it is responsible for breaking down the quaternary and tertiary structure of the protein, leaving the peptide bonds more accessible for pepsin to break. Pepsin is responsible for breaking the bonds between the amino acids, which is known as proteolysis. Lastly, the acidic environment of the stomach kills many microbes, preventing infection.
Example Question #11 : Digestive Physiology
Which of the following blood vessels carries blood that contains the most nutrients?
Femoral vein
Superior vena cava
Portal vein
Carotid arteries
Aorta
Portal vein
The portal vein carries blood from the small intestine to the liver. It has an extremely high nutrient content because it is fed with blood by the superior and inferior mesenteric veins along the small intestine. The small intestine absorbs most of the nutrients from the food that has been ingested into these vessels that take the blood directly to the liver to remove toxins prior to being distributed to the rest of the body. Essentially all nutrients that enter the body must first pass through the portal vein and liver before being distributed to other tissues.
Example Question #12 : Digestive Physiology
Which of the following is NOT a function of the liver?
Glycogenolysis
Protein metabolism
Detoxification
Bile storage
Bile storage
The liver has a variety of functions including carbohydrate metabolism and storage, as well as blood detoxification. Most hepatocytes have a developed smooth endoplasmic reticulum to facilitate detoxification or wastes absorbed from the blood. Glucose is also taken from the blood and dimerized to create glycogen. Digested proteins are also carried to the protein for metabolism. Once fully dissociated, the amino acids of digested proteins can be used to build new molecules.
Although the liver produces bile, it does not store it. Bile storage is the function of the gall bladder.
Example Question #13 : Digestive Physiology
Which of the following processes allows the liver to store excess carbohydrate precursors until necessary when blood sugar levels are low?
Gluconeogenesis
Glycogenolysis
Deglutition
Glycogenesis
Glycogenesis
The liver is capable of storing glucose from carbohydrates when blood sugar levels are normal or elevated. This is accomplished by the process of converting glucose to glycogen in the liver, or glycogenesis. Once the blood sugars are low, the liver will convert glycogen back to glucose in a process called glycogenolysis. Gluconeogenesis is the synthesis of glucose from non-carbohydrate molecules, such as amino acids and triglycerides. Deglutition is simply the technical term for swallowing, and is not involved in glucose metabolism.
Example Question #14 : Digestive Physiology
What is the purpose of the bicarbonate ions released by the pancreas?
Helps separate the chyme
Breaks down proteins
Lowers the acidity in the small intestine
Raises acidity in the stomach
Raises the pH in the stomach
Lowers the acidity in the small intestine
As chyme enters the small intestine, the pancreas will release bicarbonate ions. This not only helps lower the acidity of the chyme that has just left the stomach, but also allows enzymes in the small intestine to be at their ideal pH when functioning.
Proteases, such as chymotrypsin, break down proteins and hydrochloric acid from parietal cells in the stomach contributes to the acidity of the stomach contents.
Example Question #15 : Digestive Physiology
Within the pancreas, which cell type produces insulin?
Alpha cells
Gamma cells
Delta cells
Chromaffin cells
Beta cells
Beta cells
In the pancreas, islets of Langerhans are collections of alpha, beta, and gamma endocrine cells (these are most numerous in the tail of the pancreas). Beta cells are more centrally located and are responsible for insulin secretion. Alpha cells are peripherally located and release glucagon, while delta cells are interspersed and release somatostatin. Chromaffin cells are located in the adrenal medulla and produce catecholamines.
Example Question #16 : Digestive Physiology
Which of these structures can regenerate and can convert toxins to more soluble forms?
Pancreas
None of these.
Spleen
Lung
Liver
Liver
The liver detoxifies everything we consume and thus must have the ability to regenerate the damage from such intense metabolism. The liver converts fat soluble toxins to water soluble ones so that they can be secreted in urine. It also manages by products of regular digestion such as converting the ammonia formed from protein digestion into urea.
Example Question #17 : Digestive Physiology
A patient presents to the clinic with complaints of constant fatigue. He states that he changed his diet 6 years ago to a completely vegan diet. After doing labs, you notice the patient has megaloblastic anemia and some peripheral neuropathy. Which of the following vitamins is responsible for the findings in this patient?
Vitamin B9
None of the other answers
Vitamin B12
Vitamin B6
Vitamin C
Vitamin B12
This patient most likely has vitamin B12 deficiency. B12 is found in meats and thus a vegan individual would be deficiency in this vitamin. It takes several years to develop B12 deficiency because the liver can store B12 for a few years before signs and symptoms present of the deficiency. B12 deficiency is associated with neurological symptoms (peripheral neuropath) and macrocytic/megaloblastic anemia. B9 also presents with megaloblastic/macrocytic anemia but it does not have neurological signs or symptoms. Additionally, B9 is found in green vegetables and there is nothing in the patient's history to suggest B9 deficiency. B6 presents as sideroblastic anemia.
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