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Example Questions
Example Question #1 : Understanding Structures Of Mitosis
Which term refers to the microtuble structures that move the chromatids to opposite poles of a cell during mitosis?
Kinetochores
Spindle fibers
Centrioles
Microfilaments
Vesicles
Spindle fibers
Spindle fibers are specialized microtubule structures that guide the movement of chromosomes and chromatids during mitosis. During mitosis, the spindle fibers will bind to a protein complex (known as the kinetochore) at the center of the chromosome. The kinetochore serves as an anchor, allowing the spindle fibers to retract and separate the sister chromatids. Centrioles serve as the opposite anchor point, keeping the other end of the spindle fiber attached to the pole of the cell.
Viscles are small membrane-bound sacs that can be used to transport proteins and other molecules either within the cell, or between the cell and the extracellular matrix. Microfiliments are another component of the cytoskeleton and are frequently associated with motility; the protein actin is a microfiliment.
Example Question #1 : Understanding Structures Of Mitosis
During which stage of mitosis do the chromosomes begin to move towards opposite ends of the cell?
Metaphase
Telophase
Prophase
Anaphase
Anaphase
Recall PMAT mnemonic for remembering the steps in mitosis: prophase, metaphase, anaphase, telophase. Mitosis involves the separation of the (already-duplicated) chromosomes. The chromosomes condense, the mitotic spindle begins to form, and the nuclear envelope begins to break down during prophase. During metaphase, the chromosomes line up on the metaphase plate. In anaphase, the sister chromosomes begin getting pulled to opposite ends of the cell. Telophase is the opposite of prophase, and the cell undergoes cytokinesis.
Example Question #2 : Understanding Structures Of Mitosis
In mitosis, metaphase can be distinguished from the other stages most easily due to which of the following?
Chromosomes that are being separated by the formation of the cell plate.
Chromosomes entangled with one another, enveloped in the nuclear membrane.
Metaphase is not a stage in mitosis.
Chromosomes aligned in the middle of the plane by what is known as the metaphase plate.
Chromosomes are at separate poles with kinetochore attachments.
Chromosomes aligned in the middle of the plane by what is known as the metaphase plate.
Metaphase, by definition, is the point in which the sister chromatids align themselves along the middle of the plane which is known as the metaphase plate.
The responses explain interphase (chromosomes entangled with one another, enveloped in the nuclear membrane) and anaphase (chromosomes are at separate poles with kinetochore attachments). The other two responses are not phases of mitosis.
Example Question #33 : Cell Division
What is the role of the kinetochore?
Signal the cell to enter metaphase
Perform a check that sister chromatids have been copied properly and are identical
Act as an attachment point for spindle fibers
Bind sister chromatids together
Keep chromatin coiled
Act as an attachment point for spindle fibers
Kinetochores are protein structures located near the center of chromatids during cell division. Each chromatid has its own kinetochore so that spindle fibers can attach and pull the sister chromatids to opposite ends of the dividing cell. Note that the kinetochore assembles on the centromere region.
Example Question #1 : Understanding Stages Of Meiosis
Which event takes place during anaphase II?
Sister chromatids line up in the center of the cell
Homologous chromosomes are separated
Sister chromatids are separated
Homologous chromosomes line up in the center of the cell
Sister chromatids are separated
During prophase I, homologous chromosomes form tetrads along the center of the cell. Full chromosomes are pulled to each pole during anaphase I, resulting in two haploid cells at the end of meiosis I. During prophase II, sister chromatids align at the center of the cell in singular chromosome structures. These sister chromatids are separated during anaphase II, resulting in a total of four haploid cells.
Example Question #1 : Understanding Stages Of Meiosis
What is the first stage of meiosis during which a cell is considered haploid?
Telophase II
Metaphase I
Prophase II
Anaphase I
Prophase II
A diploid cell will have two copies of each chromosome, known as a homologous pair. A haploid cell will only have one copy of each chromosome, though the chromosome may consist of two sister chromatids.
Diploid cell: (XX)
Haploid cell: (X)
During meiosis I, the cell is diploid because the homologous chromosomes are still located within the same cell membrane. Only after the first cytokinesis, when the daughter cells of meiosis I are fully separated, are the cells considered haploid. Following this first division, the cell begins meiosis II with prophase II, making this the first haploid meiotic stage.
Example Question #2 : Understanding Stages Of Meiosis
What occurs during the S phase of the cell cycle?
The cell enters a state in which it neither divides, nor is preparing to divide
The cell grows in size, prepares mRNA and proteins, and prepares to divide
DNA is replicated, resulting in two identical sister chromatids attached at the centromere
The cell's chromatin condenses and forms chromosomes
The cytoplasm splits and forms two diploid daughter nuclei
DNA is replicated, resulting in two identical sister chromatids attached at the centromere
The S phase occurs between the G1 and G2 phases and is the stage during which DNA is replicated, and then checked for defects. Depending on the level of nutrients and energy available, the cell will either enter the G0 phase or the M phase.
During the G1 phase, the cell replicates organelles and grows in size. During the G2 phase, DNA is checked for damage and the cell prepares to divide. The M phase refers to mitosis, while the G0 phase refers to quiescence—a period during which the cell is not preparing for division.
Example Question #1 : Meiosis
During which phase of meiosis does DNA begin to condense?
Prophase I
Metaphase II
Telophase I
Metaphase I
Anaphase I
Prophase I
Mitosis is also known as "karyokinesis." "Karyo-" refers to the nucleus. (Remember that eu-KARY-ote means true ("eu-") nucleus, and pro-KARY-ote means before ("pro-") nucleus.) The "-kinesis" part of "karyokinesis" comes from the same roots as "kinetic" and refers to movement. Thus, mitosis is the movement of the nucleus. Packing of the DNA occurs in prophase of mitosis so that it's easier to move rather than having to move the loose chromatin. Think of moving forty-six strands of hundreds of yards of yarn—we would want it to be tightly coiled to make it manageable.
Example Question #1 : Meiosis
Meiosis is the process by which a ___________ cell is formed from a ___________ cell.
haploid . . . diploid
diploid . . . haploid
diploid . . . diploid
haploid . . . haploid
haploid . . . diploid
Meiosis is the process by which a haploid cell is formed from a diploid cell. The difference between haploid cells and diploid cells is that haploid cells contain one complete set of chromosomes, whereas diploid cells contain two complete sets of chromosomes. Meiosis involves the division of a diploid (2n) parent cell. The chromosomes are duplicated, but carry out two consecutive divisions. The result is four haploid (n) cells, each with half the number of chromosomes as the parent cell due to the separation of homologous pairs in meiosis I.
In contrast, mitosis is the process by which a diploid parent cell produces two diploid daughter cells.
Example Question #2 : Meiosis
Which three events most accurately describes what occurs in meiosis I?
None of these occur in meiosis I
Sister chromatids pair, cross over, then separate
Homologous chromosomes pair, cross over, then separate
Sister chromatids are duplicated, pair, then cross over
Homologous chromosomes are duplicated, pair, then separate
Homologous chromosomes pair, cross over, then separate
In meiosis I, the homologous chromosomes have already been duplicated in S phase of interphase. The sister chromatids are identical at this stage. Homologous chromosomes pair in prophase I, forming tetrads. The tetrads then cross over, exchanging genetic material. Then, the genetically-mixed tetrads line up on the metaphase plate and are separated in anaphase I. Note that after the first meiotic division, the two daughter cells are nonidentical and are haploid.
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