GRE Subject Test: Biology : Cell Membrane and Organelles

Study concepts, example questions & explanations for GRE Subject Test: Biology

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Example Questions

Example Question #81 : Cell Biology

Which of the following substances would be most capable of passing through a plasma membrane?

Possible Answers:

Amino acid

Sodium ion

Glucose

Steroid hormone

Correct answer:

Steroid hormone

Explanation:

Membranes are semi-permeable, meaning that they only allow certain compounds to cross without protein assistance. The two factors that determine permeability across a membrane are size and polarity. Polar and charged compounds very rarely cross the membrane by simple diffusion, and often require a carrier protein or pump in order to cross. Glucose and amino acids are polar, and a sodium ion carries a positive charge. These compounds will be blocked by the hydrophobic interior of the membrane, formed by the fatty acids tails of the phospholipids bilayer.

Nonpolar compounds, on the other hand, can very easily cross the cell membrane. Even larger nonpolar molecules, like steroid hormones, can easily cross the membrane via simple diffusion.

Example Question #11 : Cell Membrane And Organelles

__________ are specialized cell junctions that connect the cytoplasm of two cells and allow for the exchange of various ions and molecules.

Possible Answers:

Adherens junctions

Gap junctions

Tight junctions

Desmosomes 

Correct answer:

Gap junctions

Explanation:

As the name implies, gap junctions are literally a gap in the plasma membranes of two adjacent cells that connect their cytoplasms. These junctions allow for electrical synapses and rapid cell signaling. While most notably present in cardiac muscle, gap junctions are also present in some neural cells and receptors.

Adherens junctions anchor cells through interactions with the actin cytoskeleton. Desmosomes use cadherin proteins to anchor cells via interactions with intermediate filaments. Tight junctions are used to create barriers that selectively allow molecules through layers of epithelial cells. 

Example Question #1 : Understanding Cell Junctions

Which of the following is true about cell junctions?

Possible Answers:

Certain junctions are capable of connecting the cytoplasm of two adjacent cells to allow for the free exchange of ions and small molecules

Certain junctions can create barriers that are nearly impermeable to fluid flow

Certain types of junctions can anchor neighboring cells to one another via their cytoskeletons

All of these are true of cell junctions

Correct answer:

All of these are true of cell junctions

Explanation:

All of the choices describe functions of different types of cell junctions. Anchoring junctions (such as adherens junctions and desmosomes) use the cytoskeletons of each cell, as well as certain transmembrane proteins, to anchor the cells together. Gap junctions create gaps in the plasma membrane between two adjacent cells that connect their cytoplasms. Tight junctions are capable of forming barriers that are nearly impermeable to fluid flow. 

Example Question #83 : Gre Subject Test: Biology

Which cellular junction is most important in spreading action potentials throughout cardiac muscle?

Possible Answers:

Desmosomes

Valves

Gap junctions

Tight junctions

Correct answer:

Gap junctions

Explanation:

In order to have the action potential spread evenly and completely throughout the cardiac muscle cells, the cells need junctions that allow for ions to move between them. This action is accomplished by gap junctions between the cells. The intercalated discs between cardiac muscle cells are composed of gap junctions, and allow for electrical stimulation to travel from one cell to the next. This feature means that cardiac muscle can be depolarized and contract simultaneously.

Tight junctions are used to prevent fluid flow between cells. Desmosomes help with force transduction by linking the cytoskeletons of adjacent cells. Valves are not a type of cellular junction, and are macrostructures that prevent the backflow of fluids in vessels of the body.

Example Question #84 : Gre Subject Test: Biology

Which cellular junction acts as a barrier to prevent fluids from passing between cells?

Possible Answers:

Villi

Gap junctions

Tight junctions

Desmosomes

Correct answer:

Tight junctions

Explanation:

Cellular junctions allow cells to block materials from moving between cells, or for providing communication between cells. Tight junctions are junctions between cells that form a tight seal. This prevents water and other fluids from moving past the cells. Tight junctions are essential for maintaining concentration gradients, preventing osmosis from equilibrating ion concentrations between two regions.

Desmosomes serve to anchor the cytoskeletons of two adjacent cells, helping with force transduction. Gap junctions allow for cellular communication by creating perforations between cells through which ions and small molecules can flow. Villi are not a type of cell junction, and are structures that serve to increase cell surface area.

Example Question #1 : Understanding Cell Junctions

Which of the following is a potential function of cell junctions?

I. Anchor adjacent cells

II. Anchor the extracellular matrix

III. Communicate with neighboring cells

Possible Answers:

III only

I and III

I and II

I, II, and III

Correct answer:

I, II, and III

Explanation:

All of the choices presented describe functions of cell junctions. Adherens junctions and desmosomes are responsible for anchoring neighboring cells to one another. Hemidesmosomes help anchor the extracellular matrix in place, binding the cell membrane to proteins in the basal lamina or matrix. Gap junctions are an example of junctions that connect the cytoplasm of two neighboring cells and allow for communication via ions and other small molecules.

Example Question #1 : Other Organelles

How are proteins imported into the nucleus?

Possible Answers:

Passive diffusion through nuclear pore complexes

With the assistance of special proteins known as importins 

Proteins are only exported from the nucleus

Translocation through nuclear pore complexes while they are being translated by membrane-bound ribosomes

Correct answer:

With the assistance of special proteins known as importins 

Explanation:

Nuclear import and export is tightly regulated by importin and exportin proteins. These proteins interact with target proteins to carry them into or out of the nucleus, respectively. Proteins cannot passively diffuse into the nucleus and they are not translocated into the nucleus during translation.

Example Question #2 : Understanding The Nucleus

Which of the following is true regarding the nucleus?

Possible Answers:

The nucleus is surrounded by multiple membranes

The nucleus is the site of assembly for ribosomal subunits

The nucleus is studded with many openings called nuclear pore complexes

All of these answers

Correct answer:

All of these answers

Explanation:

All of these choices are correct regarding the nucleus. Nuclear pore complexes are incredibly important for regulating nuclear import and export. Ribosomal subunits are assembled in the nucleolus, which is a portion of the nucleus. The nucleus is covered by two lipid bilayers, which constitute the nuclear envelope.

Example Question #1 : Understanding The Nucleus

What provides structural support for the nucleus and binds chromatin?

Possible Answers:

Nuclear envelope

Lamina 

Nucleolus

Nuclear pores

Cytoskeleton

Correct answer:

Lamina 

Explanation:

The correct answer is lamina. This is a fibrous network of filaments within the nucleus that provides architectual support similar to the cytoskeleton. Chromatin also is held in place by association with the lamina. 

Example Question #1 : Understanding Mitochondria And Chloroplasts

The inner mitochondrial membrane is organized into cristae, which essentially results in a series of folds within the mitochondria. Which of the following best describes the primary advantage to having cristae in inner compartments of mitochondria?

Possible Answers:

Decreased requirement for input to the mitochondrion due to increased presence of glucose on the cristae membrane. 

Increased spacing of cytochromes to increase metabolic output.

Increased surface area for the biochemical reactions to produce ATP, thus increasing metabolic output of each mitochondrion. 

Protection of integral membrane proteins from the extremely basic intracristal space of the mitochondria. 

ATP synthase is sequestered from the outer membrane, thus increasing its potential energy. 

Correct answer:

Increased surface area for the biochemical reactions to produce ATP, thus increasing metabolic output of each mitochondrion. 

Explanation:

ATP synthase and cytochromes stud the inner membrane, and more surface area means that more of them can be present in each mitochondrion. This increases the capacity to generate ATP. 

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