The cartoon is centered around the use of child labor in the United States. Answering this question requires you to know a little bit about this topic, or at least enough about the various eras mentioned to be able to make a logical guess. Of course, in modern times, the use of child labor is banned in the United States; however, during the industrial revolution it was exceedingly common to find children, particularly boys, as young as eight or ten working in factories. This is generally true of all the western nations during the industrial revolution. Towards the end of the nineteenth century, and in the early twentieth century, there was a massive social backlash against the use of child labor. It played an important role in the Progressive movement of the first two decades of the twentieth century.

The man shown looking disdainfully towards the map of the United States is Uncle Sam. He appears throughout American history as a personification ("human representation") of the American Republic. He is particularly prominent in political cartoons and government propaganda. His counterpart in England is called John Bull.

Just because Andrew Jackson is dressed as the King of England does not mean there is any evidence to suggest he was born in Britain, supported the British war effort, or was friends with the British King. Nor does it directly suggest that Andrew Jackson did not enjoy much popular support; however, in his hand Jackson is holding a piece of paper that says “veto,” which suggests he was not afraid to use the Presidential veto when given the opportunity.

In the cartoon Jackson is dressed as a King, an authoritarian ruler, and standing on a ripped-up copy of the United States’ Constitution. The author of this cartoon is clearly suggesting that Jackson should not be considered a truly democratic leader, but as something approaching a totalitarian ruler.

President Theodore Roosevelt’s domestic policies were in part defined by his opposition to large corporations, called “trusts.” His presidency was also defined by his imperialist and environmentalist (at least by the standards of the day) policies; but, in this cartoon Roosevelt is pictured as a hunter going after the standard oil trust, the beef trust, and the hard-coal trust. So, it seems logical to answer that the cartoon centers around his reputation as a “trustbuster.”

In this cartoon Andrew Jackson, one-time President of the United States, is shown dressed as a King and standing atop ripped-up copies of the United States’ Constitution and the Internal Improvements Bill. The headline reads “Born to command.” The tone is therefore meant to be mocking and ironic. The author is suggesting that Jackson believes he is born to command and thinks of himself as a ruler closer to a King than a President.

The primary meaning behind this cartoon is that the use of child labor represents an affront to American society and to American values. The cartoon depicts a map of the United States with a big "blot" or "stain" on the map represented by child labor. The man is most likely meant to be Uncle Sam, looking disdainfully at the use of child labor.