Biochemistry : Fundamental Macromolecules and Concepts

Study concepts, example questions & explanations for Biochemistry

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Example Questions

Example Question #23 : Lipids

Which of the following can be used to describe fatty acids?

Possible Answers:

Inorganic

Amphipathic 

Hydrophilic

Amphoteric

Hydrophobic

Correct answer:

Amphipathic 

Explanation:

Fatty acids are composed of a carboxylic acid head and a long carbon chain. The carbon chain is non-polar, while the carboxylic acid head is polar. A molecule with both a polar and non-polar parts is known as amphipathic. The word amphoteric means a molecule that can act as either an acid or a base. Finally, just as a fatty acid has both polar and non-polar ends, those same ends are also hydrophilic and hydrophobic, respectively.  

Example Question #552 : Biochemistry

What is an amphipathic molecule?

Possible Answers:

A molecule that has both polar and nonpolar region

Acidic ions

A class of wax molecules

Basic ions

Molecules in crystalline form

Correct answer:

A molecule that has both polar and nonpolar region

Explanation:

An amphipathic molecule has both polar and nonpolar domains. Long-chain fatty acids are examples of amphipathic molecules.

Example Question #24 : Lipids

Poison ivy, poison oak, and poison sumac produce a compound called urushiol. Urushiol is a mixture of compounds containing catechols with long-chain alkyl groups. The severity of the allergic reaction depends on the degree of unsaturation of the alkyl groups.

If you are exposed to poison ivy, which treatment would be most effective?

Possible Answers:

Wash the area with saline

Wash the area with soap and water

Wash the area with cold water

Wash the area with dilute vinegar or lemon juice

Wash the area with soap, water, and baking soda (sodium bicarbonate)

Correct answer:

Wash the area with soap, water, and baking soda (sodium bicarbonate)

Explanation:

Soap and water will work, as urushiol is amphipathic, but the addition of sodium bicarbonate is more effective. Sodium bicarbonate is a weak base and will make the urushiol more polar - and therefore more water-soluble. 

Example Question #551 : Biochemistry

Which substance do you expect to be most soluble in water?

Possible Answers:

Carbon dioxide

Ammonia

Methane

Carbon trioxide

Nitrogen

Correct answer:

Ammonia

Explanation:

Ammonia, NH3, will be the most soluble in water simply because polar substances dissolve in polar solvents. This follows the principle that "like dissolves like." Ammonia and water are both polar due to the presence of lone pairs of electrons combined with a lack of geometrical symmetry (water is bent and ammonia is trigonal pyramidal).

Carbon dioxide and nitrogen are linear, negating any potential polarity. Methane is tetrahedral, and lacks any polarized bonds. Carbon trioxide is tigonal planar, negating polar interactions due to symmetry.

Example Question #2 : Essential Properties Of Water

What is true about the solubility of electrolytes in water?

Possible Answers:

No reactions can occur between aqueous electrolytes

They are usually only sparingly soluble in water

They often form super-saturated aqueous solutions

They are all insoluble in water

They readily dissolve in water

Correct answer:

They readily dissolve in water

Explanation:

Electrolytes readily dissolve and ionize in water. The term "electrolyte" refers to a molecule that will produce ions in solution, and can be synonymous with "salt" in certain contexts, as well as acidic and basic compounds.

Example Question #1 : Essential Properties Of Water

What property of water makes it a good solvent for ionic salts?

Possible Answers:

Low dielectric constant

van der Waals forces

High polarity

Molecular symmetry

Small molecule size

Correct answer:

High polarity

Explanation:

When dealing with solutions, it is helpful to remember that solubility depends on polarity and that "like dissolves like." Polar solutes (ionic salts) dissolve well in polar solvents (water); the same goes for nonpolar solutes and solvents.

Example Question #552 : Biochemistry

Which of the following statements about water are incorrect?

Possible Answers:

Hydrophobic interactions are driven by the increase in enthalpy that water molecules achieve by excluding a non-polar solute

In water, linear hydrogen bonds are stronger than bent hydrogen bonds

Water has a high heat of vaporization and high surface tension

Water has a tetrahedral structure when considering lone pairs and a bent molecular structure when not considering lone pairs

Liquid water is 15% less H-bonded than ice
Correct answer:

Hydrophobic interactions are driven by the increase in enthalpy that water molecules achieve by excluding a non-polar solute

Explanation:

Hydrophobic interactions are driven by the increase in entropy (not enthalpy) that water molecules achieve by excluding a nonpolar solute. In the hydrophobic effect, water initially forms cage-like structures called clathrates around the nonpolar solute, which is entropically unfavorable. However, entropy is regained when the water molecules exclude the solute and interact with each other in a disordered manner.

Example Question #554 : Biochemistry

The primary reason that water is liquid at room temperature is because of __________.

Possible Answers:

Cohesion

Adhesion

Surface tension

High density

Correct answer:

Cohesion

Explanation:

Cohesion is defined as attraction between the same type of molecule. Water attracts other water molecules because it is polar and has partial charges. This attraction means that water has strong intermolecular forces even at room temperature and more thermal energy is required to vaporize it. Adhesion involves the attraction of a substance with a container or surface.

Example Question #2 : Essential Properties Of Water

Which of the following is false about water?

Possible Answers:

Its electrons are symmetrically positioned around the molecule. 

The hydrogen atoms have a slight net positive charge.

Hydrogen bonds join together water molecules.

Water's total charge is neutral.

Water is polar, with an electropositive and electronegative region.

Correct answer:

Its electrons are symmetrically positioned around the molecule. 

Explanation:

The electrons around water are not symmetrically positioned; rather, they are distributed toward the oxygen atom, which is highly electronegative. Hence, water's two hydrogen atoms have a net positive charge. Nonetheless, the total charge on water is neutral, with electropositive and electronegative regions, rendering it polar. This polarity allows water molecules to hydrogen-bond with each other.

Example Question #2 : Essential Properties Of Water

Which of the following polymers is not formed by condensation?

Possible Answers:

Proteins

Polystyrene

Nylon

Polysaccharides

Nucleic acids

Correct answer:

Polystyrene

Explanation:

The important point here is that biological polymers are basically all condensation polymers. In the case of proteins, polysaccharides (carbohydrates), and nucleic acids (like DNA and RNA), synthesis occurs via a loss of a water molecule. Non-biological molecules can also be formed via condensation, such as nylon, which also often has water as its by-product. Polystyrene is an addition polymer; upon formation, monomers do not lose any molecules. Bonds are only rearranged. Although it may seem counterintuitive, the fact is that in nature, polymers do not typically form this way.

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