AP Biology : AP Biology

Study concepts, example questions & explanations for AP Biology

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Example Questions

Example Question #2 : Understanding The Cell Membrane

How are integral proteins introduced into the cellular membrane of an eukaryotic cell?

Possible Answers:

Cells have all of the necessary membrane proteins upon completing mitosis

Endocytosis brings in the necessary proteins and incorporates them into the membrane

Exocytosis supplies the membrane with the necessary proteins, which are present on the secretory vesicle

Cytoplasmic ribosomes translate the necessary proteins and send them to the membrane

Correct answer:

Exocytosis supplies the membrane with the necessary proteins, which are present on the secretory vesicle

Explanation:

Exocytosis allows the membrane of secretory vesicles to be incorporated into the cellular membrane. This expands the membrane surface, while including the desired proteins into the membrane. Due to fluidity and the mosaic model of the membrane, these proteins can then distribute to other areas on the cell surface.

Endocytosis does the opposite process, and involves a pinching off of the cell membrane in order to transport incoming materials. Ribosomes translate the proteins, however, processing of membrane proteins occurs in the endoplasmic reticulum and Golgi body, ultimately packaging membrane proteins in secratory vesicles for exocytosis.

Example Question #5 : Understanding The Cell Membrane

Where would aspartic acid, an amino acid with a negatively charged side chain, most likely be found in a transmembrane protein?

Possible Answers:

Inside the cell

Within the membrane interior

Outside the cell

Within the membrane interior, outside the cell, or inside the cell

Outside or inside the cell

Correct answer:

Outside or inside the cell

Explanation:

Any amino acid with a charged side chain will be polar. Membranes have hydrophobic tails on the interior, and hydrophilic heads facing the outside and inside of the cell. Since polar molecules are charged, they will interact with the hydrophilic parts of the environment, and therefore they will not be found within the membrane interior.

Example Question #3 : Understanding The Cell Membrane

What would happen to a cell that contains 4.0 moles of solute inside it if it were placed in a cup of water with 2.0 moles of sodium chloride?

Possible Answers:

It would burst

Half of the NaCl would move into the cell to make even concentrations

Nothing

It would swell

It would shrivel

Correct answer:

Nothing

Explanation:

This question is tricky because we need to remember that if there are 2.0 moles of NaCl in the water, then there are 4.0 moles of solute because it will dissociate to one  and one ; therefore, this is an isotonic environment and there will be no net movement of water. When a compound dissociates in solution, it is the ion concentration that will affect the movement of water, rather than the amount of initial solid.

Example Question #4 : Understanding The Cell Membrane

The negative charge inside cells is primarily maintained by __________.

Possible Answers:

the membrane being less permeable to sodium ions than to potassium ions

the membrane being less permeable to potassium ions than to sodium ions

the sodium-potassium pump

the plasma membrane being impermeable to water

Correct answer:

the sodium-potassium pump

Explanation:

If there was no expenditure of energy when determining the voltage across the plasma membrane, there would be equal electrical charge on both sides of the bilayer as the ions travel to reach equilibrium. This means that ATP must be used in order to establish a resting potential, keeping the ions away from electrical equilibrium.

The sodium-potassium pump is an example of how ions can be pumped against their electrochemical gradients in order to establish a negative voltage inside the cell. The cell membrane is not permeable to sodium or potassium.

Example Question #8 : Understanding The Cell Membrane

Of the following, which is most likely to pass through the cell membrane via passive transport?

Possible Answers:

A charged ion

A steroid molecule

A peptide hormone

Water, when traveling from a highly hypertonic environment into a cell

Glucose

Correct answer:

A steroid molecule

Explanation:

Passive transport is simple diffusion, without the aid of any protein channels. Since the plasma membrane is composed of a lipid bilayer, the molecules that most readily cross it are small and hydrophobic.

Remember that water is polar; hydrophobic molecules are nonpolar, like lipids and oils. Steroids are derived from cholesterol and are extremely lipid-soluble, so they can cross the membrane unassisted. Large, polar molecules (such as glucose or peptides) and charged ions need channel proteins to facilitate their crossing. Water can diffuse across the membrane, but only when it is moving down its concentration gradient. The answer choice given has water moving from a hypertonic (high-solute, or low-water) environment into a cell, which cannot occur passively.

Example Question #9 : Understanding The Cell Membrane

What is the major factor limiting the size of a cell?

Possible Answers:

Ratio of surface area to volume

Availability of nutrients

Concentration of water in the cytoplasm

Number of membrane-bound organelles 

Correct answer:

Ratio of surface area to volume

Explanation:

While the availability of nutrients is a tempting answer, it is important to remember that even in incredibly nutrient-rich environments cells reach a maximum size. The concentration of water in the cytoplasm and the amount of membrane bound organelles will not really have any effect on the size of the cells.

The correct answer is the surface area to volume ratio because it dictates the amount of chemical activity carried out per unit of time. The volume of the cell determines its metabolic needs: larger cells hold more biological material and require more energy and maintenance. The surface area of the cell determines its ability to transport nutrients and absorb nutrients, providing the tools to maintain the cell's volume. A large surface area to volume ratio is essential for the cell.

Example Question #10 : Understanding The Cell Membrane

What are the main components of a phospholipid?

Possible Answers:

Three fatty acids and a glycerol backbone

A polar head group, two fatty acids, and a glycerol backbone

Two fatty acids, a glycerol backbone, and a cholesterol molecule

A polar head group, two fatty acids, and a glycogen backbone

Correct answer:

A polar head group, two fatty acids, and a glycerol backbone

Explanation:

Phospholipids found in the plasma membrane are comprised of a polar head group, two fatty acids, and a glycerol backbone. The phosphate group carries a negative charge, allowing it to interact with polar aqueous environments. The two fatty acid tails form the hydrophobic region of the bilayer interior. The glycerol backbone forms the structural component for linking the polar and non-polar regions.

Glycogen is a polymer of glucose sugars, and is not found in phospholipids. Triglycerides are composed of three fatty acids and a glycerol backbone.

Example Question #41 : Cellular Biology

Which of the following molecules can freely diffuse through the plasma membrane?

Possible Answers:

Potassium ions

Oxygen

Cholesterol

Glucose

Correct answer:

Oxygen

Explanation:

Membranes are permeable to small, nonpolar molecules like oxygen. Though oxygen is commonly involved in polar bonds, the diatomic molecule has no net dipole, allowing it to cross the membrane. This function is essential for gas exchange, in which oxygen passes from the alveoli of the lungs into adjacent capillaries.

Cholesterol is too large to freely cross the membrane, and requires the assistance of a facilitating protein channel. Glucose is also too large and carries a polar aldehyde or ketone group, preventing it from freely crossing the membrane. Potassium ions are small, but charged. Though they could pass between the lipids of the membrane, they would be repelled by the hydrophobic region in the lipid bilayer interior.

Example Question #42 : Cellular Biology

Which of the following is a component of the cell membrane?

Possible Answers:

RNA

Glucose

Cholesterol

Ribosomes

All these are components of the cell membrane

Correct answer:

Cholesterol

Explanation:

The cell membrane is primarily made of a phospholipid bilayer. The phospholipids consist of a polar phosphate head and two nonpolar lipid tails, oriented so that the tails of each side of the bilayer face one another. Numerous proteins are found in the membrane as well, contributing to the fluid-mosaic model.

Cholesterol molecules are found in the lipid interior of the membrane, between the two layers. Its primary function is to prevent adhesion of the nonpolar tails. By stopping the tails from sticking to one another, the cholesterol helps maintain the fluidity of the membrane.

Glucose, RNA, and ribosomes are not found in the cell membrane.

Example Question #43 : Cellular Biology

Why are most cells microscopic in size?

Possible Answers:

The amount of plasma membrane is minimized relative to the more stable cytoplasm

The ratio of cell surface area to volume is maximized

More cells are compacted into an organ when maintaining a reasonable size

Smaller cells allow unicellular organisms to be undetected by predators

Smaller cells require fewer nutrients, which increases their probability for survival

Correct answer:

The ratio of cell surface area to volume is maximized

Explanation:

Cells obtain all of their nutrients across their plasma membranes. To ensure cellular function it is essential to maximize surface area, which corresponds to the amount of plasma membrane. This creates a large area available for diffusion of the necessary nutrients. While it may be more efficient for an organism to produce a few large cells instead of many small cells, the advantage of a large area for diffusion outweighs the cost of energy. Essentially, the surface area is the region of nutrient source and the volume (cytoplasm) is the region of nutrient consumption. For the cell to survive, it must maximize the amount of source nutrients and minimize the amount of nutrient consumption.

The statements that smaller cells are difficult to be detected by predators and require fewer nutrients for survival are both true, but are not the major reasons why cells are microscopic in size.

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