NCLEX-RN : General Biology

Study concepts, example questions & explanations for NCLEX-RN

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Example Questions

Example Question #32 : Endocrine And Immune Systems

Which of the following antibacterial enzymes is present saliva?

Possible Answers:

Lingual lipase

Lysozyme

Amylase

Kallikrein

Correct answer:

Lysozyme

Explanation:

While all of the enzymes listed are present in saliva, lysozyme is the only enzyme listed that has antibacterial properties. This enzyme, present not only in saliva but also in tears, sweat, and breast milk, damages bacterial cell walls, making it an important part of the innate immune system. Amylase breaks down carbohydrates, lipase breaks down lipids, and kallikrein breaks down proteins.

Example Question #291 : General Biology

Which of the following cell counts is particularly diminished in patients with AIDS, and is used to measure disease extent?

Possible Answers:

Neutrophils

Monocytes

CD8 T-cells

CD4 T-cells

Platelets

Correct answer:

CD4 T-cells

Explanation:

The correct answer is "CD4 T-cells." 

In AIDS, which is the most progressed stage of HIV, the cell type that is most significantly diminished is CD4 T-cells. Often times, the degree of disease progress of HIV and AIDS is established by monitoring the patient's CD4 T-cell count across the course of the illness. The CD4 count guides differential diagnoses when patients with HIV or AIDS present with various complaints, and also guides what prophylactic measures (e.g. antibiotics, antifungals) are administered to these patients. 

While CD8 T-cell, monocyte, platelet, and neutrophil counts may each be decreased for various reasons in patients with HIV and AIDS, the most substantial association between diminished cell count and HIV/AIDS is that of CD4 T-cells.

Example Question #1 : Lung And Alveoli

How many lobes total are there in the human lungs?

Possible Answers:

Correct answer:

Explanation:

There are five lobes total in the human lungs: the right lung has three lobes (the upper lobe, the middle lobe, and the lower lobe) while the left lung has two lobes (the upper lobe and the lower lobe).

Example Question #2 : Lung And Alveoli

What is the name for the topmost part of the lung?

Possible Answers:

The hilum

The trachea

The lingula

The apex

Correct answer:

The apex

Explanation:

The topmost part of the lungs is the apex. This area extends into the neck above the 1st rib and is the location auscultated for a diagnosis of a pancost tumor. The lingula of the lung is a small flap of the lowest part of the upper lobe of the left lung. The hilum is the entry point of the lung for the bronchi, pulmonary artery and vein, and nerves. The trachea is not a part of the lung at all; it is the cartilaginous tube that connects the pharynx and larynx to the lung.

Example Question #3 : Lung And Alveoli

Which of the following lists of airway structures is in order from largest to smallest?

Possible Answers:

Trachea - bronchi - bronchiole - alveoli

Trachea - bronchiole - bronchi - alveoli

Trachea - alveoli - bronchiole - bronchi

Bronchi - trachea - bronchiole - alveoli

Correct answer:

Trachea - bronchi - bronchiole - alveoli

Explanation:

The largest airway structure is the trachea. This branches into two smaller bronchi, which enter the left and right lung and bifurcate further into smaller bronchioles. The bronchioles give way into the smallest structures of the lung, the tiny grape-like clusters of alveoli.

Example Question #4 : Lung And Alveoli

What structure of the lung is primarily responsible for controlling volume of air flow during respiration?

Possible Answers:

The bronchioles

The alveoli

The bronchi

The trachea

Correct answer:

The bronchioles

Explanation:

The main mediator of air flow during respiration is the bronchiole. These tiny airways are wrapped in smooth muscle, which allows them to contract or relax in order to restrict or increase air flow in the lung. The trachea and bronchioles are cartilaginous rather than muscular, and are unable to constrict, while the wall of the alveolar sac is also devoid of smooth muscle, made up only of epithelial cells, capillaries, and connective tissue.  

Example Question #1 : Circulatory And Respiratory Systems

Which of the following allows debris to be removed from the lung?

Possible Answers:

Bronchiolar constriction and dilation

The mucociliary escalator

Granulation

The pleural lymph system

Correct answer:

The mucociliary escalator

Explanation:

The system by which debris is removed from the lung is termed the mucociliary escalator. This is made up of two parts: the mucus produced by respiratory goblet cells, and the wave-like movement of cilia covering the bronchioles and bronchi of the lung. Bacteria and particles  of debris are caught in the mucus coating the cilia, which is then passed in waves upward toward the trachea. Once it clears the trachea and enters the pharynx, it can either be coughed out or swallowed.  

Example Question #1 : Circulatory And Respiratory Systems

The major alveolar cell type, making up 95% of alveolar cells, is type I. Only 5% of alveolar cells are type II, yet they serve a vital function in respiratory physiology. What is the function of type II alveolar cells?

Possible Answers:

They are the site of gas exchange

They nourish the type I cells

They are important for the integrity of the alveolar connective tissue

They secrete surfactant

Correct answer:

They secrete surfactant

Explanation:

Type II alveolar cells secrete pulmonary surfactant, a lipoprotein complex that is essential for lung function. This surfactant acts to break up the surface tension of fluid coating the lung airspaces, allowing for alveolar compliance and reducing the buildup of fluid in the lung. Lack of surfactant can lead to atelectasis, or collapse of part of the lung.

Example Question #1 : Respiratory System

Which of the following is the primary muscle of respiration?

Possible Answers:

The sternocleidomastoid

The diaphragm

The intercostals

The scalenes

Correct answer:

The diaphragm

Explanation:

The most important muscle of respiration is the diaphragm, followed by the intercostals. The sternocleidomastoid and scalenes are considered accessory muscles of respiration. 

Example Question #2 : Circulatory And Respiratory Systems

How do bronchioles respond to an increase in the partial pressure of carbon dioxide in the alveoli?

Possible Answers:

They dilate

They constrict 

The bronchioles do not respond to changes in the partial pressure of carbon dioxide

They secret mucus

Correct answer:

They dilate

Explanation:

Carbon dioxide has paracrine effects in the airway, causing the smooth muscle of bronchioles to relax. When the partial pressure of carbon dioxide in the alveoli increases, the bronchioles dilate. This allows for increased ventilation.

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