MCAT Biology : Biology

Study concepts, example questions & explanations for MCAT Biology

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Example Questions

Example Question #1 : Nervous System And Nervous Tissue

Which component of a neuron is responsible for electochemically stimulating nearby cells?

Possible Answers:

Soma

Axon

Nucleus

Dendrite

Correct answer:

Axon

Explanation:

The axon ends in a terminal bud, which transmits signals to target cells by releasing neurotransmitters across the synapse. The soma is the body of the cell and contains the nucleus. This is where the majority of protein synthesis occurs. The dendrites receive electrochemical stimuli from other neurons and cells and transmit the signal to the soma and axon.

Example Question #1 : Neuron Structure And Types Of Neurons

The primary purpose of the sodium/potassium pump is to __________.

Possible Answers:

export two potassium ions, import three sodium ions, and establish cell membrane resting potential

export three sodium ions, import two potassium ions, and establish cell membrane resting potential

export two sodium ions, import three potassium ions, and cause an action potential

export two potassium ions, import three sodium ions, and cause an action potential

export two sodium ions, import three potassium ions, and establish cell membrane resting potential

Correct answer:

export three sodium ions, import two potassium ions, and establish cell membrane resting potential

Explanation:

Na+/K+ ATPase always exports three sodium ions out of the cell and imports two potassium ions into the cell. The export of three positively charged sodium ions for the import of only two positively charged potassium ions results in a net -70mV charge across the cell membrane, which is known as the cell membrane resting potential.

Example Question #2 : Nervous System And Nervous Tissue

Which of the following is NOT true of the neural soma and axon?

Possible Answers:

Lack of myelination in the soma

Increased ribosomal activity in the axon hillock

Increased mitochondrial activity in the axon

Nodes of Ranvier distinct on the axon only

Decreased voltage-gated sodium channel density in the soma

Correct answer:

Increased ribosomal activity in the axon hillock

Explanation:

All of the following are true characteristics of the neural axon and soma except “increased ribosomal activity in the axon hillock.” The axon hillock is a site of neurotransmitter transport. These molecules are produced and packaged in the soma of the neuron, before being translocated to the axon hillock via microtubule tracks. There is little to no ribosomal activity in the axon of a neuron, since most ribosomes are located near the nucleus of a cell, which is the site of mRNA release.

Example Question #2 : Neuron Structure And Types Of Neurons

What is the source of neurons and glia that innervate the pancreas?

Possible Answers:

Somatic nervous system

Enteric nervous system

Cranial nerves

Central nervous system

Correct answer:

Enteric nervous system

Explanation:

The enteric nervous system (ENS) is a component of the autonomic nervous system, which is a component of the peripheral nervous system. The ENS is responsible for innervating the digestive organs and, thus, regulating digestion.

The central nervous system is composed of the brain and spinal cord, while the peripheral nervous system prolifertates the body. The somatic nervous system is under voluntary control, while the autonomic is involuntary. The cranial nerves are a set of specialized nerves that branch directly off of the spinal cord.

Example Question #2 : Nervous System And Nervous Tissue

Ependymal cells are a type of glial cells that __________.

Possible Answers:

synthesize and secrete myelin 

help create the blood-brain barrier 

release neurotransmitters into the synapse 

phagocytose bacteria or damaged neurons within the central nervous system

secrete cerebrospinal fluid in the central nervous system

Correct answer:

secrete cerebrospinal fluid in the central nervous system

Explanation:

Along with capillaries, the ependymal cells create the choroid plexus. The choroid plexus is responsible for synthesizing and secreting cerebrospinal fluid around the brain and the spinal cord. 

Example Question #1 : Action Potentials And Synapse Biology

In humans, nerve impulses are transmitted with the coordinated action of sodium and potassium ion channels. These channels open in a specific sequence, to allow for membrane potential changes to take place in a directional manner along the length of an axon. 

Figure 1 depicts a single phospholipid layer of a cell membrane, and three transmembrane channels important to action potential propagation.

 

Untitled

At the distal end of the axon shown in Figure 1, what process directly drives the fusion of synaptic vesicles to discharge neurotransmitter into the synaptic cleft?

Possible Answers:

The influx of magnesium at the synaptic terminal

The influx of sodium at the synaptic terminal

The influx of calcium at the synaptic terminal

The influx of potassium at the synaptic terminal

The influx of chloride at the synaptic terminal

Correct answer:

The influx of calcium at the synaptic terminal

Explanation:

Calcium is a very common vehicle that drives membrane fusion, including the fusion of synaptic vesicles with the synaptic cell membrane. This allows the ejection of neurotransmitter into the synaptic cleft.

Example Question #1 : Action Potentials And Synapse Biology

Which of the following is false regarding synapses?

Possible Answers:

In a chemical synapse, there is an influx of calcium ions into the postsynaptic neuron upon neurotransmitter binding

The gap between a presynaptic and a postsynaptic neuron is called a synaptic cleft

In a chemical synapse, neurotransmitters bind to receptors on the postsynaptic neuron

The most common type of synapse found in cardiac cells are electrical synapses

Correct answer:

In a chemical synapse, there is an influx of calcium ions into the postsynaptic neuron upon neurotransmitter binding

Explanation:

There are two types of synapses: the chemical synapse and the electrical synapse. Chemical synapses are more common than electrical synapses, and use neurotransmitters (chemicals) to propagate action potentials. Electrical synapses have tunnels between cells, called gap junctions, that quickly transmit signals from one cell to the other. Electrical synapses are found extensively in the heart, since it is essential to have quick signal transmission between cardiac cells.

In chemical synapses an action potential reaches the end of a presynaptic neuron, which causes neurotransmitters to be released from the presynaptic neuron. These neurotransmitters bind to receptors on the postsynaptic neuron and initiate a signal transduction pathway in the postsynaptic neuron. The space between the presynaptic and postsynaptic neuron is called the synaptic cleft. Synaptic clefts are important regions where neurotransmitters are released and regulated.

Calcium ions play an important role in chemical synapses. Once an action potential arrives at the presynaptic neuron terminal, calcium ion channels on the presynaptic neuron become permeable to calcium ions. This facilitates the movement of calcium ions into the presynaptic neuron. Influx of calcium ions signals the presynaptic neuron to release neurotransmitters into the synaptic cleft, which eventually bind to receptors on the postsynaptic neuron. The calcium ions do not enter the postsynaptic neuron at the synapse.

Example Question #2 : Action Potentials And Synapse Biology

A/An __________ synapse uses gap junctions to transmit signals, and a/an __________ synapse transmits the signals the fastest.

Possible Answers:

chemical . . . chemical

electrical . . . electrical

electrical . . . chemical

chemical . . . electrical

Correct answer:

electrical . . . electrical

Explanation:

Electrical synapses have two main characteristics. First, they transmit signals through specialized tunnels between cells called gap junctions. Gap junctions facilitate movement of molecules and ions between cells. This movement enables transmission of signals between adjacent cells. Second, electrical synapses have a much higher speed of signal transmission than chemical synapses. This occurs because the signals in electrical synapses are transmitted directly from one cell to the next via gap junctions. In chemical synapses, however, signals are transmitted indirectly via neurotransmitters, which decreases the speed of signal transmission.

Example Question #1 : Action Potentials And Synapse Biology

Which of the following is characteristic of a chemical synapse?

I. Signal transmission involves neurotransmitters

II. They are bidirectional

III. They are more common than electrical synapses

Possible Answers:

I, II, and III

I and III

II only

I only

Correct answer:

I and III

Explanation:

A chemical synapse is a type of synapse that uses neurotransmitters to transmit signals. A presynaptic neuron receives an action potential, which prompts neurotransmitters to be released into the synaptic cleft. These neurotransmitters traverse across the synaptic cleft and bind to receptors on the postsynaptic neuron. Binding of neurotransmitters initiates a signal pathway in the postsynaptic neuron.

One of the characteristics of a chemical synapse is that it is unidirectional. This means that the signal can only be propagated in one direction. The signal is always transmitted from the presynaptic to the postsynaptic neuron, never the other way around.

Chemical synapses are indeed more common than electrical synapses. Most nerves, neuromuscular junctions, and major organs in the body use chemical synapses to transmit action potentials. The only major exception is the heart; cardiac cells in the heart use electrical synapses to transmit signal from one cell to the other.

Example Question #4 : Action Potentials And Synapse Biology

In a chemical synapse, which structure contains the neurotransmitter receptors?

Possible Answers:

Axon of the presynaptic neuron

Dendrites of the postsynaptic neuron

Dendrites of the presynaptic neuron

Axon of the postsynaptic neuron

Correct answer:

Dendrites of the postsynaptic neuron

Explanation:

In a chemical synapse, the presynaptic neuron transmits a signal to the adjacent postsynaptic neuron. The postsynaptic neuron receives this signal via neurotransmitters. Recall that a neuron has directionality, with dendrites on one end and an axon on the other end. Dendrites receive an outside signal (signal enters neuron), whereas an axon transmits the signal to an adjacent neuron or muscle (signal exits neuron). This means that the axon end of the presynaptic neuron transmits the signal to the dendrite end of the postsynaptic neuron via a chemical synapse.

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