Human Anatomy and Physiology : Nervous System

Study concepts, example questions & explanations for Human Anatomy and Physiology

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Example Questions

Example Question #31 : Nervous System

At which vertebrae would you enter to remove cerebrospinal fluid (CSF) from the back?

Possible Answers:

Posterior sacral foramina

L2

L4/L5

T3/T4

Correct answer:

L4/L5

Explanation:

When performing a spinal tap you enter the intervertebral space at the L3/L4 or L4/L5 level. This is because the spinal cord ends around L1/L2. Nerves continue past this point as part of the cauda equina, however they are not in danger of being pierced as they move out of the way of the needle. The needle will pass through various layers until the subarachnoid space where CSF is located.

Example Question #1417 : Human Anatomy And Physiology

At what level does one perform a lumbar puncture?

Possible Answers:

L1/L2 or L2/L3

Only L1/L2

L4/L5 or L3/L4

Only L3/L4

Correct answer:

L4/L5 or L3/L4

Explanation:

In human adults the spinal cord (caudal tip) usually ends at the level of L1/L2. Thus lumbar punctures are performed between the L3 and L4 vertebrae or between L4 and L5, so there is no risk of damage to the spinal cord. 

Example Question #32 : Nervous System

You suspect that a patient may have an injury to her dorsal scapular nerve. What abnormal movement pattern would make you suspect this?

Possible Answers:

Excess scapular upward rotation

Excess scapular elevation

Excess scapular internal rotation ("winging")

Excess scapular downward rotation

Correct answer:

Excess scapular upward rotation

Explanation:

Although electrodiagnostic testing would be needed to definitively diagnose a dorsal scapular nerve pathology, excess scapular upward rotation could suggest dysfunction of this nerve. Because the dorsal scapular nerve innervates the rhomboid major and minor, which are downward scapular rotators (as well as scapular elevators, and adductors) injury to this nerve would decrease eccentric control of upward rotation, causing excessive movement in that direction. Excess scapular internal rotation is associated with injury to the long thoracic nerve, not the dorsal scapular nerve.

Example Question #1 : Help With Nervous System Injuries And Disorders

Loss of which nerve function would diminish the ability to supinate the hand and forearm?

Possible Answers:

Ulnar nerve

Radial nerve

Axillary nerve

Median nerve

Correct answer:

Radial nerve

Explanation:

The supinator muscle is innervated by the radial nerve and functions to supinate the forearm. The biceps brachii muscle also helps supinate the forearm and is innervated by the musculocutaneous nerve.

The median nerve and ulnar nerve mostly serve to innervate the muscle of the hand and wrist. The axillary nerve innervates the teres minor and deltoid.

Example Question #2 : Help With Nervous System Injuries And Disorders

A football player is found to have damaged is anterior interosseous nerve (branch of the median nerve). Which of the following hand motions will he be unable to perform?

Possible Answers:

Peace sign

"OK" sign

Form an L with his thumb and ring finger

Thumbs up

Correct answer:

"OK" sign

Explanation:

The anterior interosseous nerve (AIN) is a motor branch of the median nerve that innervates the flexor pollicus longus, pronator quadratus, and the radial half of flexor digitorum profundus. Injury to the AIN results in weakness of the pincer function of the thumb and index fingers. When asked to make an "OK sign, people with an AIN injury make a triangle instead.

Example Question #3 : Help With Nervous System Injuries And Disorders

A 23-year old man was involved in a high-speed motor vehicle accident and presents with an open fracture of the right mid-shaft humerus. In the trauma bay he complains of numbness in the dorsum of his right hand. He is taken immediately to the operating room where an intramedullary rod was placed. There were no complications during surgery. Five days after the surgery, the man still complains of numbness in the dorsum of his right hand and is also unable to extend his right elbow.

What other abnormality do you expect to see in this patient?

Possible Answers:

Wrist drop

Carpal tunnel syndrome

Erb-Duchenne palsy

Anterior interosseous nerve syndrome

Claw hand

Correct answer:

Wrist drop

Explanation:

You would expect this patient to exhibit wrist drop.

This is a multi-step thinking question that gives you many clues as to what might be wrong in the patient. First, let's sort out the facts that we are given:

1. The patient has a break in the middle of his right humerus.

2. Patient has numbness on the dorsal surface of his ipsilateral (same side) hand.

3. Patient is unable to extend (straighten) his elbow.

Now let's ask ourselves some questions about these facts:

1. What is the anatomy of the humerus, specifically in the mid-shaft? (hint: what "groove" is located there?)

2. What nerve provides sensation to the dorsum of the hand?

3. What muscles extend the elbow and what nerve innervates those muscles?

The spiral groove is located in the middle of the humerus, which is where the radial nerve wraps around the bone. The radial nerve supplies sensation to the dorsum of the hand. The triceps brachii are responsible for straightening the elbow and are innervated by the radial nerve. Fomr the given information, we know the radial nerve is likely injured, but we need to figure out what else could be impacted by this deficit. The radial nerve innervates the extensor muscles of the forearm, allowing one to extend at the wrist. If these muscles were to be deficient, as exhibited in a radial nerve injury, one would expect the wrist to not be able to extend, and thus manifest as wrist drop.

Let's touch on the other answer choices for further learning:

Claw hand is seen in ulnar nerve injury such as Klumpke's paralysis and manifests as a weakness/inability to flex the wrist (flexor carpi ulnaris), the metacarpophalagneal joints of the 4th and 5th digits in extension (interosseous muscles), and interphalagneal joints of the 4th and 5th digits in flexion (also interossei and lumbricals).

Erb-Duchenne Palsy or Erb's Palsy is an injury to the upper trunk of the brachial plexus that occurs when the head is violently displaced from the shoulder as happens in a difficult breech delivery or trauma.  This will involve the suprascapular, musculocutaneous, and often axillary nerves. Patients present with the arm adducted (deltoid muscle deficient), elbow extended (biceps brachii deficient), and forearm pronated (also biceps brachii). This is referred to as the "waiter's tip" position.

Carpal tunnel syndrome is entrapment of the median nerve in the carpal tunnel (beneath the transverse carpal ligament). Patients present with numbness and tingling in the palm of the hand as well as 1st, 2nd, 3rd, and half of the 4th digits. There may be atrophy of the thenar eminence, as well as weakness in thumb opposition. Symptoms are worse at night.

Anterior interosseous nerve (AIN) syndrome is a rare median nerve entrapment that will manifest similar to carpal tunnel syndrome, but is distinguished by its presentation of only motor symptoms and lack of nighttime symptoms.

Example Question #4 : Help With Nervous System Injuries And Disorders

While carrying a pot of food to the dinner table, you accidentally bump your elbow against a counter in the kitchen and immediately feel pain shoot down your forearm to your ring finger and pinky. Recalling your anatomy, which nerve did you compress and where did you irritate it?

Possible Answers:

Ulnar nerve at the condylar groove

Median nerve at the bicipital aponeurosis

Median nerve by the pronator teres

Radial nerve by the extensor carpi radialis brevis

Ulnar nerve within Guyon’s canal

Correct answer:

Ulnar nerve at the condylar groove

Explanation:

The ulnar nerve was compressed at the condylar groove. This common phenomenon is often referred to as the "funny bone". The ulnar nerve provides sensory innervation to half of the 4th digit and the entire 5th digit, as well as the medial aspect of the hand.

The ulnar nerve arises from the lower trunk of the brachial plexus, from spinal roots C8 and T1. It travels medially in the arm in the medial cord and courses posteriorly around the medial epicondyle of the elbow in an indentation known as the condylar groove. This is the spot that you hit when you hit your "funny bone."

Other common places of ulnar nerve entrapment are at the cubital tunnel of the elbow or the ulnar tunnel (Guyon's canal) of the wrist. Compression of the radial nerve by the extensor carpi radialis brevis leads to posterior interosseous nerve (PIN) syndrome. The median nerve is commonly compressed at the bicipital aponeurosis and the pronator teres to give pronator syndrome.

Example Question #5 : Help With Nervous System Injuries And Disorders

A 22-year old man with a history of a supracondylar fracture of the left humerus 15 years ago presents with numbness and weakness in the medial aspect of his left palm, as well as his pinky and ring finger, for the past two weeks. On physical exam there was decreased sensation in his left pinky and ring finger as well as atrophy of his hypothenar eminence.

What is the most likely cause of his current condition?

Possible Answers:

Carpal tunnel syndrome

Tardy ulnar nerve palsy

Thoracic outlet syndrome

Klumpke’s paralysis

Posterior Interossesous Nerve (PIN) syndrome

Correct answer:

Tardy ulnar nerve palsy

Explanation:

This man is suffering from tardy ulnar nerve palsy as a result of cubitus varus.

We are told that the patient has numbness and weakness in his medial hand and 4th and 5th digits; this area is innervated by branches of the ulnar nerve. Commonly seen in these patients are also atrophy of the hypothenar region, as those muscles are also innervated by the ulnar nerve.

Tardy ulnar nerve palsy is a condition in which the ulnar nerve is irritated as a result of cubitus varus of the distal humerus. This condition develops after a child suffers a supracondylar fracture of the humerus with healing resulting in deformity, especially of the medial epicondyle where the ulnar nerve runs.

Incorrect choices:

Carpal tunnel syndrome is entrapment of the median nerve in the carpal tunnel (beneath the transverse carpal ligament). Patients present with numbness and tingling in the palm of the hand as well as 1st, 2nd, 3rd, and half of the 4th digits. There may be atrophy of the thenar eminence as well as weakness in thumb opposition. Symptoms are worse at night.

Klumpke's paralysis is a result of injury to the lower trunk of the brachial plexus, or the spinal roots C8 and T1. The classic manifestation is the claw hand, characterized by weakness/inability to flex the wrist (flexor carpi ulnaris), the metacarpophalagneal joints of the 4th and 5th digits in extension (interosseous muscles), and interphalagneal joints of the 4th and 5th digits in flexion (also interossei and lumbricals).

Posterior interossesous nerve (PIN) syndrome is compression of a branch of the radial nerve in the radial tunnel resulting in weakened extension of the hand and wrist.

Thoracic outlet syndrome is caused by an abnormal insertion of the anterior and middle scalene muscles and the cervical rib attached to C7 that causes nerve and vascular compression. There are a wide range of symptoms and may cause vascular issues as well.

 

Example Question #6 : Help With Nervous System Injuries And Disorders

A 24-year old gang leader presents the trauma bay in stable condition with a knife wound to his right shoulder after a fight. After assuring that he only suffered that single wound, you proceed to test his right upper extremity. You find that he is unable to abduct or extend his shoulder, and he is also unable to extend his elbow; however, he has full strength in flexing his shoulder and elbow.

You figure that the knife must have cut a part of the brachial plexus. What part has been injured?

Possible Answers:

Median nerve

C8 and T1

Upper trunk

Anterior division

Posterior cord

Correct answer:

Posterior cord

Explanation:

The knife probably hit the posterior cord of the brachial plexus.

To answer this question we need to think about what deficits are exhibited by the patient:

1. Inability to abduct the shoulder

2. Inability to extend the shoulder

3. Inability to extend the elbow

Let's think about what nerves are deficient:

1. The axillary nerve supplies the deltoid muscle, which function to abduct the shoulder.

2. The latissimus dorsi extends the shoulder and is supplied by the thoracodorsal nerve.

3. Elbow extension is accomplished by the triceps brachii, which is innervated by the radial nerve.

So we know the axillary, thoracodorsal, and radial nerves are deficient. These three nerves all arise from the posterior cord of the brachial plexus, however they also receive innervation from the upper trunk of the brachial plexus. We know that the patient is able to fully flex the shoulder and elbow, which is accomplished by the coracobrachialis and biceps brachii, respectively. These two muscles are both innervated by the musculocutaneous nerve. Because the musculocutaneous nerve is intact, we know the upper trunk of the brachial plexus has not been affected, and that the knife must have pierced the posterior cord.

C8 and T1 supply the lower trunk of the brachial plexus, which gives rise to the ulnar nerve. The anterior divisions supply the medial and lateral cords of the brachial plexus. The median nerve is supplied by the medial and lateral cords of the brachial plexus and innervates the functions of wrist and hand flexion.

Example Question #5 : Help With Nervous System Injuries And Disorders

The phrenic nerve originates in the neck and innervates the diaphragm for breathing. Oftentimes when the diaphragm is irritated, pain is felt in a different body part that is served by the same spinal nerves, known as “referred pain”. A 72-year old nursing home resident is found to have an abscess below his right diaphragm, but complains of pain somewhere else. Where do you expect his pain most likely to be?

Possible Answers:

Left forearm

Left axilla

Right hand

Right nipple area

Right shoulder

Correct answer:

Right shoulder

Explanation:

Irritation of the phrenic nerve can result in referred pain to the ipsilateral shoulder. In this case, since the abscess irritates the right disphragm, the patient will have pain in his right shoulder.

The phrenic nerve is supplied by C3, C4, and C5 and innervates the diaphragm for breathing purposes (C3, 4, 5 keep the diaphragm alive). Thinking back to sensory innervation of the shoulder, we know that the suprascapular nerve (C3, C4) and axillary nerve (C5, C6) supply the shoulder area. Specifically, the referred pain to the ipsilateral shoulder from phrenic nerve injury/irritation is known as "Kehr's Sign".

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