GRE Subject Test: Biology : Chromatin and Chromosomes

Study concepts, example questions & explanations for GRE Subject Test: Biology

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Example Questions

Example Question #1 : Understanding Structures And Proteins In Dna

Which of the following proteins is necessary for nucleosome formation?

Possible Answers:

Chromatin

Nuclear lamin

Histones

Histone methyltransferases

DNA ligase

Correct answer:

Histones

Explanation:

The correct answer is histones. DNA wraps around histones to form the nucleosomes. Further condensation of many nucleosomes results in chromatin (DNA state). Histone methyltransferases are important enzymes that modify histones during epigenetic gene regulation; however, they are not necessary for nucleosome formation. DNA ligase is responsible for catalyzing the formation of phosphodiester bonds, but is unrelated to nucleosome formation.

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