Genetics : Mendelian and Population Genetics

Study concepts, example questions & explanations for Genetics

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Example Questions

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Example Question #85 : Genetics

If you cross a red long pedal poppy with genotype RrLl and a white short pedal poppy with genotype  rrll, what should my F1 progeny look like?

Possible Answers:

1/8- white and short pedals

1/8- white and long pedals

1/4- red and short pedals

1/2- red and long pedals

1/4- red and long pedals

1/4- white and long pedals

1/4- red and short pedals

1/4- white and short pedals

1/2- red and long pedals

1/4- white and long pedals

1/4- white and short pedals

1/2- red and long pedals

1/2- white and short pedals

Correct answer:

1/4- red and long pedals

1/4- white and long pedals

1/4- red and short pedals

1/4- white and short pedals

Explanation:

Using a punnet square, we can see that:1/4 will be red with long pedals, 1/4 will be red with short pedals, 1/4 will be white with long pedals, and 1/4 will be white with short pedals.

     RL     Rl       rL       rl

rl RrLl     Rrll      rrLl      rrll

Example Question #85 : Genetics

What is a lethal gene?

Possible Answers:

a recessive only gene that can cause death in an individual

a dominant or recessive gene that can cause death in an individual

a dominant only gene that can cause death in an individual

a gene that blocks other genes from being expressed

Correct answer:

a dominant or recessive gene that can cause death in an individual

Explanation:

A lethal gene is any gene that, when expressed with another lethal gene, can cause death in an individual. It can be dominant or recessive in nature.

Example Question #87 : Genetics

A few monkeys were moved from a zoo in New York to a theme park in Ohio. Over generations, the population of monkeys in Ohio becomes significantly different than the one in the zoo in New York. Which of the following terms best describes this scenario?

Possible Answers:

Genetic drift

Independent assortment

Founder effect

Bottleneck effect

Non-random mating

Correct answer:

Founder effect

Explanation:

Founder effect is when a few individuals from a population are moved to a different environment and over generations, their genetic makeup differs from their original population. 

A bottleneck effect would require most of the population to die from natural cause, instead of being moved. Independent assortment has to do with alleles and hence is not relevant. Both non-random mating and genetic drift would not cause a change in the genetic makeup of the population. 

Example Question #24 : Mendelian And Population Genetics

Consider an alien species that has two major physical traits that follow the principles of Mendelian genetics: horn arrangement and horn color. For this species, forehead horns can either be arranged in a trio of small horns or as a single large horn. Horn color can be either black or white.

The trio arrangement is a dominant trait, and alleles for horn arrangement use the letter "T." The white coloration is also a dominant trait, and alleles for horn color use the letter "W."

Which of the following would produce the highest proportion of offspring having three black horns when crossed with an alien heterozygous for both traits?

Possible Answers:

ttWW

ttWw

TTww

TtWw

Correct answer:

TTww

Explanation:

The question asks us to think about offspring with black horns in a trio formation. That means these offspring would be showing a recessive trait for coloration (black) and a dominant trait for arrangement (three horns). Since only one dominant allele is required for a dominant trait to "show through," the horn arrangement gene must have at least one dominant allele, which we can write as T[ ]. However, for a recessive trait to be displayed, both alleles must be recessive: therefore, these offspring need to have ww for coloration. Thus, we are concerned with those offspring that have a genotype of T[ ]ww– that is, offspring with genotypes TTww or Ttww.

We already are given one parent's genome in the question itself: "heterozygous for both traits" means this alien has one dominant and one recessive allele for each gene. Thus, the known parent's genotype is TtWw. We can first eliminate any answer choices that can't result in any three-black-horned babies at all. The known parent has a dominant allele for horn arrangement, meaning that there is at least some chance of this parent's children having three horns, no matter who s/he mates with. We should thus focus our energy more towards looking at the possibility of black-horned babies. If this parent mated with another alien who had only dominant genes on the coloration gene, then all their children would inherit at least one dominant gene for coloration (at least one W) and thus none would have a chance of having black horns. This means we can eliminate the choice with two dominant W's: the other parent won't be ttWW.

Next, let's consider a special situation in Mendelian genetics called a dihybrid cross. This is the mating of two parents who are both heterozygous for two traits. In this example, this mating would be our known parent (TtWw) crossed with another double heterozygote (another TtWw). The proportion of offspring phenotypes for a dihybrid cross is known to be 9:3:3:1. This means that for every 16 babies, we expect that nine will show both dominant traits; three will show dominant trait A and recessive trait B; three will show recessive trait A and dominant trait B; and one will show both recessive traits. We're concerned with those offspring that show one dominant and one recessive trait, so that means that for TtWw x TtWw, 3 out of 16 offspring will have three black horns.

From here, we probably want to look at Punnett square for the other two parent options. For a Punnett square involving two traits, we want 16 total squares representing offspring. When writing the possible allele combinations (as one allele from trait A and one allele from trait B) each parent could donate to the child, we essentially "repeat" each allele once. That is, we write the first trait A allele twice, the second trait A allele twice, the first trait B allele twice, and the second trait B allele twice. For a TtWw x ttWw cross, this looks like:

 

TtWw

 

 

ttWw

 

TW

Tw

tW

tw

tW

TtWW

TtWw

ttWW

ttWw

tw

TtWw

Ttww

ttWw

ttww

tW

TtWW

TtWw

ttWW

ttWw

tw

TtWw

Ttww

ttWw

ttww

The offspring with horns in a trio arrangement (at least one T) and black coloration (two w's) are underlined and italicized so they are easier to see. From this we can see that for TtWw x ttWw, 2 out of 16 offspring will have three black horns.

Let's do the same thing for the last answer choice for the second parent's genotype: TTww.

 

TtWw

 

 

TTww

 

TW

Tw

tW

tw

Tw

TTWw

TTww

TtWw

Ttww

Tw

TTWw

TTww

TtWw

Ttww

Tw

TTWw

TTww

TtWw

Ttww

Tw

TTWw

TTww

TtWw

Ttww

Wow! This means that for TtWw x TTww, 8 out of 16 offspring will have three black horns.

Now let's compare our options:

  • TtWw x ttWW: 0/16 three black horns
  • TtWw x TtWw: 3/16 three black horns
  • TtWw x ttWw: 2/16 three black horns
  • TtWw x TTww: 8/16 three black horns

Clearly, crossing with TTww gives the TtWw parent's offspring the best chance of have three black horns, so that is our correct answer.

Example Question #21 : Mendelian And Population Genetics

Consider the statement, "In human body cells, genes are paired, and both genes work together to determine the trait expressed; however, when gametes are created, only one gene from each pair is transferred to each gamete."

Which of the following principles is best summarized by this statement?

Possible Answers:

None of these; this statement is not true

The law of recombination

The law of independent assortment

The law of segregation

The law of dominance

Correct answer:

The law of segregation

Explanation:

The statement presented in the question is true of human genetics and helps explain how genetic material from both parents combines to form a child when the parents' gametes unit in fertilization. The best choice here is the Mendelian law of segregation, which essentially means the same thing as the statement provided. Two of the other choices—the laws of dominance and independent assortment—are also Mendelian laws of inheritance, but they are not directly related to the question material. They refer respectively to the ideas that the dominant version of the two versions of a gene (alleles) an individual possess will be expressed, and that genes are distributed to each gamete independently of each other so that traits on different genes are not correlated with each other.

While recombination is an important part of meiosis and thus genetic inheritance, it isn't considered a "law" per se. As a concept, it is still not the best answer choice.

Example Question #21 : Mendelian And Population Genetics

In the context of the Hardy-Weinberg law, which of the following is true regarding random mating?

I. It refers to individuals mating without choosing mates based on their traits.

II. It contributes to a Hardy-Weinberg equilibrium since it provides all alleles an equal chance of being passed on to progeny.

III. It is characteristic of and consistent with natural selection.

Possible Answers:

I & III

I & II

I, II, & III

II & III

I only

Correct answer:

I & II

Explanation:

All of these are correct, true statements except choice III. Random mating indeed refers to individuals mating without choosing mates based on their traits, and this allows all alleles to be passed down to the next generation at roughly the same rate; however, in reality, organisms often show non-random preferences when choosing mates. They tend to prefer mates with traits that will make them survive longer, better able to raise offspring, more capable of protecting the family group, etc. With that said, it's clear that certain individuals have a much lower chance of successively mating—for example, if they have a genetic disorder that makes them weaker or less healthy than the average member of the species.

Since individuals choose mates non-randomly, the most reproductively fit individuals pass down their genes at a significantly higher rate than other individuals. This is also called "survival of the fittest" and is a major concept tied up with natural selection. As such, choice III is incorrect, since natural selection is essentially opposite to random mating.

Example Question #21 : Mendelian And Population Genetics

Consider an alien species that shows simple dominant-recessive inheritance of ear shape, in which rounded ears are dominant and pointed ears are recessive. These species meets the requirements for a Hardy-Weinberg equilibrium, and of all the alleles for ear shape present in the population, 75% are dominant and 25% are recessive.

If there are 4000 individuals in the population, how many would you expect to have rounded ears?

Possible Answers:

2250

250

3750

3000

1500

Correct answer:

3750

Explanation:

Since we are given in the question that this alien population meets the requirements for a Hardy-Weinberg equilibrium, we know it is appropriate to use the Hardy-Weinberg equation to think about genotypes and phenotypes. Recall that the Hardy-Weinberg equation is:

Here, p represents the percentage of dominant alleles in the population, while q represents the percentage of recessive alleles in the population. Since all alleles in the population must be either dominant or recessive, the sum of those percentages is always 1:

With that in mind, we can use the information in the question to determine that p = 0.75 and q = 0.25. The proportion of individuals that are homozygous dominant is given by p x p; that are homozygous recessive, q x q; that are heterozygous, 2 x p x q. Since rounded ear shape is dominant to pointed ear shape, we expect that homozygous dominant and heterozygous individuals will all show the rounded ear phenotype. Let's find the total percentage of those individuals that exist in the whole population:

These means 93.75% of the individuals in this population display rounded ear shape; however, this question asked for the number of individuals, so we want to multiply this proportion by the total number of individuals in the population (given as 4000):

This means that the correct answer is that we can expect 3750 of the 4000 total individuals to show rounded ear shape.

Example Question #24 : Mendelian And Population Genetics

Consider an alien species that shows simple dominant-recessive inheritance of ear shape, in which rounded ears are dominant and pointed ears are recessive. These species meets the requirements for a Hardy-Weinberg equilibrium, and of all the alleles for ear shape present in the population, 75% are dominant and 25% are recessive.

If there are 4000 individuals in the population, how many would you expect to have pointed ears?

Possible Answers:

250

2000

3750

750

1000

Correct answer:

250

Explanation:

Since we are given in the question that this alien population meets the requirements for a Hardy-Weinberg equilibrium, we know it is appropriate to use the Hardy-Weinberg equation to think about genotypes and phenotypes. Recall that the Hardy-Weinberg equation is:

Here, p represents the percentage of dominant alleles in the population, while q represents the percentage of recessive alleles in the population. Since all alleles in the population must be either dominant or recessive, the sum of those percentages is always 1:

With that in mind, we can use the information in the question to determine that p = 0.75 and q = 0.25. The proportion of individuals that are homozygous dominant is given by p x p; that are homozygous recessive, q x q; that are heterozygous, 2 x p x q. Since pointed ear shape is recessive to rounded ear shape, we expect that only homozygous recessive individuals will show the rounded ear phenotype. Let's find the total percentage of those individuals that exist in the whole population:

These means just 6.25% of the individuals in this population display pointed ear shape; however, this question asked for the number of individuals, so we want to multiply this proportion by the total number of individuals in the population (given as 4000):

This means that the correct answer is that we can expect 250 of the 4000 total individuals to show rounded ear shape.

Example Question #21 : Mendelian And Population Genetics

If one parent has the alleles of gene a, : AA and the other parent has the alleles of gene a: Aa, what are the possible combinations the child could receive? 

Possible Answers:

AA, Aa, or aa

AA or Aa

aa or Aa

Aa or aa

Correct answer:

AA or Aa

Explanation:

The correct answer here is AA and Aa. We can figure this out by drawing a punnet square as drawn below: 

 

As you can see from above, there are only two options from this combination of gene alleles. If you chose any of the other options, try drawing a punnett square by placing the first parents' genes on one end of the table and the other on the top. See if you can match each allele to another one from the other parent. You should obtain the same results as above. 

Example Question #22 : Mendelian And Population Genetics

Which option describes the phenomenon where a rare or naturally occurring disaster wipes out a certain generation of the population so that the resulting population hardly resembles the original parent generations?

Possible Answers:

devolution effects

founder effect

famine effects

bottleneck effect

Correct answer:

bottleneck effect

Explanation:

The correct answer is the bottleneck effect, because this is where a natural or rare disaster wipes out an existing generation to alter the gene pool for future generations. If you chose founder effect it may have been because of the relation to bottleneck. Remember that the founder effect, however, is when the beginning population is very small resulting in a small gene pool from the start of the population. If you chose de-volution, remember that this is the opposite of progressive evolution. Famine is an example of natural disaster, however, does not equate the loss of genes

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