Biochemistry : Other Lipid Catabolism Concepts
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Example Question #41 : Lipid Catabolism
What happens when the acetyl-CoA produced from beta-oxidation can not enter into the Krebs Cycle due to a lack of oxaloacetate from starvation?
The acetyl-CoA molecules combine to form acetoacetyl-CoA which is used as energy
The acetyl-CoA molecules form ketone bodies
The acetyl-CoA molecules combine to form 3-hydroxy-3-methyl-glutaryl-CoA which is used as energy
The acetyl-CoA molecules go through the gluconeogenesis pathway to form more glucose
The acetyl-CoA molecules combine with another Krebs cycle intermediate to continue with oxidative respiration
The acetyl-CoA molecules form ketone bodies
When oxaloacetate is low in the body as a result of starvation, acetyl-CoA can no longer combine with it to continue through the Krebs cycle. Oxaloacetate can go through gluconeogenesis to form more glucose, however acetyl-CoA does not. Instead, the acetyl-CoA molecules go through a series of steps (acetoacetyl-CoA and 3-hydroxy-3-methyl-glutaryl-CoA are intermediate molecules in these steps) to form ketone bodies.
Example Question #42 : Lipid Catabolism
Which of the following statements is true about the role of apolipoprotein B (ApoB)100 in lipid metabolism?
I. ApoB 100 is synthesized by the liver.
II. ApoB 100 is a component of very low density, intermediate density and low density lipoproteins circulating in the blood.
III. ApoB 100 is a ligand for the LDL (low density lipoprotein) receptor in cells requiring intake of cholesterol.
IV. ApoB 100 is encoded by the same gene that produces ApoB 48.
I and II
I, II, III, and IV
I and IV
I, II, and III
II, III, and IV
I, II, III, and IV
Apoliporoteins carry lipids in the blood as lipids are insoluble. ApoB100 is a protein found on different types of lipoproteins circulating in the body. ApoB 48 is another apolipoprotein that is present on chylomicrons. Both ApoB 100 and ApoB 48 are encoded by the ApoB gene, but ApoB 48 is shorter than ApoB 100 and is produced in the intestine.
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