Biochemistry : Macromolecule Fundamentals

Study concepts, example questions & explanations for Biochemistry

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Example Questions

Example Question #91 : Macromolecule Fundamentals

A researcher is analyzing a compound. He finds that it has the same structure as glucose, but has an altered configuration at one of the stereogenic centers. What can the researcher conclude about the compound?

I. It is an epimer of glucose

II. It is an aldose

III. It could be fructose

Possible Answers:

I and II

III only

I only

II only

Correct answer:

I and II

Explanation:

The question states that the molecule has the same structure as glucose, except at one stereogenic center. Recall that epimers are structural isomers that differ at one stereogenic center; therefore, glucose and the compound are epimers. The epimers of glucose include galactose and mannose. All three molecules have a molecular formula of .

Recall that aldoses are carbohydrates that have an aldehyde group at one of the carbons. Glucose and all of its epimers have an aldehyde group at the first carbon; therefore, this compound is an aldose.

Fructose is a ketose that has a ketone group in the second carbon. Recall that aldehydes and ketones have carbonyl groups; therefore, they are not considered stereogenic centers (to be a stereogenic center you need to have four distinct functional groups on a carbon). Since fructose differs from glucose at a non-stereogenic center, this molecule cannot be fructose. Note that fructose also has a different molecular formula (). 

Example Question #5 : Monosaccharides And Carbohydrates

Which of the following carbohydrates is most likely to be found in an open chain?

Possible Answers:

A triose

A hexose

A pentose

A heptose

Correct answer:

A triose

Explanation:

Only 1% of all sugars that have five or more carbons are found in an open chain, thus any sugar that has five or more carbons will be most likely found in its cyclic form. Of the four choices a triose is the only one that has less that five carbons (it has three) the others have 5 (pentose), 6 (hexose), and 7 (heptose).

Example Question #512 : Biochemistry

If a monosaccharide has a single carbonyl group situated between two carbon atoms, which of the following best describes that monosaccharide's classification?

Possible Answers:

Ribose

Aldohexose

Ketose

Glucose

Aldose

Correct answer:

Ketose

Explanation:

Given no other information about how many carbons are in the chain, any monosaccharide with a carbonyl group on a carbon between two others and not at the terminal carbon of the chain is called a ketose. Aldoses are when the carbonyl group is at the end of the chain. Ribose and aldohexose are incorrect because 1) ribose is too specific, we do not know anything about the structure and ribose indicates a specific monosaccharide, and 2) aldohexose has an aldehyde group, not a ketone group. 

Example Question #513 : Biochemistry

What is a furanose?

Possible Answers:

A five-carbon open chain sugar

A six-carbon open-chain sugar

A sugar that contains a six-membered ring as part of its cyclical structure

A sugar that contains a five-membered ring as part of its cyclical structure

Correct answer:

A sugar that contains a five-membered ring as part of its cyclical structure

Explanation:

A furanose is defined as a cyclical sugar structure with a five-membered ring. By contrast, a pyranose is a cyclical sugar structure with a six-membered ring.

Example Question #7 : Monosaccharides And Carbohydrates

What two sugars is lactose composed of?

Possible Answers:

Galactose and sucrose

Glucose and galactose

Glucose and fructose

Glucose and sucrose

Glucose and glucose

Correct answer:

Glucose and galactose

Explanation:

Three common simple sugars are: glucose, fructose, and galactose. Combining these simple sugars leads to the formation of more complex sugar molecules. Glucose and fructose make sucrose. Glucose and galactose make lactose. Two glucose molecules make maltose. 

Example Question #8 : Monosaccharides And Carbohydrates

What is a pyranose?

Possible Answers:

A six-carbon open-chain sugar

A five-carbon open-chain sugar

A sugar that contains a six-membered ring as part of its cyclic structure

A sugar that contains a five-membered ring as part of its cyclic structure

Correct answer:

A sugar that contains a six-membered ring as part of its cyclic structure

Explanation:

A pyranose is a carbohydrate that includes a ring. It is not an open-chain carbohydrate. Additionally, this term is reserved for six-membered, not five-membered carbohydrate ring structures. A sugar which contains a five-membered ring as part of its cyclic structure is called a furanose.

Example Question #9 : Monosaccharides And Carbohydrates

What type of process is occurring as carbohydrates are broken down to carbon dioxide?

Possible Answers:

Reduction

Oxidation

Substitution

Elimination

Proteolysis

Correct answer:

Oxidation

Explanation:

As carbohydrates are broken down, they are oxidized to carbon dioxide . This process, cellular respiration, begins during glycolysis. Reduction is the opposite of oxidation, and would indicate a loss of oxygen. Elimination refers to the removal of a functional group, which does not occur during this process. In substitution, one functional group is replaced with another, which also does not accurately describe this process. Finally, proteolysis refers to the breakdown of proteins, not carbohydrates.

Example Question #92 : Macromolecule Fundamentals

Most mammals are unable to metabolize which of the following disaccharides?

Possible Answers:

Sucrose only

Cellobiose only

Cellobiose and lactose

Lactose only

Maltose and sucrose

Correct answer:

Cellobiose and lactose

Explanation:

Most mammals are unable to digest beta glycosidic bonds, such as the bonds in cellobiose and lactose. Maltose and sucrose both are connected via alpha glycosidic bonds, and can be digested by mammals.

Note: Most mammals are unable to digest lactose after infancy. It is only through a genetic mutation that many humans now are able to ingest lactose well into adulthood.

Example Question #513 : Biochemistry

What is a lactone?

Possible Answers:

A cyclic ketone

A cyclic ether

A cyclic alcohol

A cyclic ester

Correct answer:

A cyclic ester

Explanation:

This is a fact question. A lactone is a cyclic ester, which is a ring of two or more carbon atoms and one oxygen atom with a ketone at one of the carbons adjacent to the other oxygen. Lactones are usually formed via a reaction of a carboxylic acid with a hydroxyl group or halogen atom present in the same molecule.

Example Question #93 : Macromolecule Fundamentals

Which of these cannot be digested by mammals?

Possible Answers:

Maltose

Lactose

Cellulose

Sucrose

Correct answer:

Cellulose

Explanation:

Maltose is a disaccharide formed from two glucose molecules. Mammals use the enzyme maltase to digest maltose. Lactose is a disaccharide formed from one glucose and one galactose molecule. Mammals use the enzyme lactase to digest lactose. Sucrose is a disaccharide formed from one glucose and one fructose molecule. Mammals use the enzyme sucrase to digest sucrose. Mammals cannot digest cellulose because they do not have the necessary enzymes to do so in their digestive tracts.

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