Biochemistry : Types of Inhibition

Study concepts, example questions & explanations for Biochemistry

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Example Questions

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Example Question #41 : Enzyme Kinetics And Inhibition

Enzyme A and Enzyme B are inhibited by two unknown inhibitors. The result of the inhibition on A is that the  decreases, but there is no change in the The  and  on Enzyme B both decrease. What type of inhibition do Enzyme A and Enzyme B undergo respectively?

Possible Answers:

Uncompetitive, noncompetitive

Competitive, uncompetitive

Noncompetitive, uncompetitive

Uncompetitive, competitive

Noncompetitive, competitive

Correct answer:

Noncompetitive, uncompetitive

Explanation:

A competitive inhibitor acts the increase the  of a reaction, but does not alter the . This does not describe the inhibition on Enzyme A or Enzyme B. A noncompetitive inhibitor decreases the , but does not change the . This is the inhibition that is described on Enzyme A. An uncompetitive inhibitor decreases both the  and the . This is the inhibition that is described on Enzyme B.

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