NCLEX : NCLEX

Study concepts, example questions & explanations for NCLEX

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Example Questions

Example Question #1 : Other Immune Physiology

In what tissue do T lymphocytes mature?

Possible Answers:

The thymus 

The bone marrow

The liver

The spleen

Correct answer:

The thymus 

Explanation:

T lymphocytes are so titled because they mature in the thymus, unlike B lymphocytes, which mature in the bone marrow. The thymus is located in the anterior superior mediastinum, ventral to the heart and dorsal to the sternum. It is most active in the neonatal and pre-adolescent periods, afterwards, it degenerates and is replaced with adipose tissue. 

Example Question #2 : Other Immune Physiology

Lymphoid progenitors are produced in which of the following tissues?

Possible Answers:

The liver

All of these

Gut associated lymphoid tissue (GALT)

The bone marrow

Correct answer:

All of these

Explanation:

Lymphoid progenitor cells are produced in all of the following tissues: the liver, the bone marrow, spleen, and gut associated lymphoid tissue (mainly found in the liver and intestines). However, note that the vast majority of all blood cells are produced in the red bone marrow of long bones by hematopoietic stem cells. 

Example Question #3 : Other Immune Physiology

Which immune cell is specialized for immunity against multicellular parasites?

Possible Answers:

Basophils

Natural killer cells

Monocytes

Eosinophils

Correct answer:

Eosinophils

Explanation:

While all of the cells listed may have some indirect involvement in the overall response to a parasitic infection, eosinophils are the only immune cells that are specialized to respond to multicellular parasites, especially helminths such as hookworms and pinworms. 

Example Question #2 : Other Immune Physiology

Mast cells contain high concentrations of which of the following?

Possible Answers:

Histamine

All of these

Tryptase

Heparin

Correct answer:

All of these

Explanation:

Mast cells are rich in granules that contain high concentrations of heparin, histamine, and trypsin, among other preformed proteases. These granules also contain serotonin and various eicosanoids. The function of mast cells is primarily to regulate immune (inflammatory) responses to allergens.

Example Question #4 : Other Immune Physiology

Which of the following would be considered to part of nonspecific immunity?

Possible Answers:

Plasma cells

Macrophages

CD8 T cells

Memory cells

Correct answer:

Macrophages

Explanation:

Macrophages, the main blood cells responsible for phagocytosis of debris, bacteria, and virally infected cells, are part of the nonspecific immune response. While they are able to recognize self versus non-self proteins, they are not uniquely sensitive to any particular non-self protein type. Rathe, they phagocytose foreign matter as well as cellular debris. Plasma cells, memory cells, and CD8 T cells are all lymphocytes, and as such they are all part of the adaptive or "specific" immune system, meaning that they are uniquely sensitive to particular pathogenic proteins.

Example Question #4 : Other Immune Physiology

Which of the following antibacterial enzymes is present saliva?

Possible Answers:

Lysozyme

Kallikrein

Lingual lipase

Amylase

Correct answer:

Lysozyme

Explanation:

While all of the enzymes listed are present in saliva, lysozyme is the only enzyme listed that has antibacterial properties. This enzyme, present not only in saliva but also in tears, sweat, and breast milk, damages bacterial cell walls, making it an important part of the innate immune system. Amylase breaks down carbohydrates, lipase breaks down lipids, and kallikrein breaks down proteins.

Example Question #291 : General Biology

Which of the following cell counts is particularly diminished in patients with AIDS, and is used to measure disease extent?

Possible Answers:

CD8 T-cells

Neutrophils

CD4 T-cells

Platelets

Monocytes

Correct answer:

CD4 T-cells

Explanation:

The correct answer is "CD4 T-cells." 

In AIDS, which is the most progressed stage of HIV, the cell type that is most significantly diminished is CD4 T-cells. Often times, the degree of disease progress of HIV and AIDS is established by monitoring the patient's CD4 T-cell count across the course of the illness. The CD4 count guides differential diagnoses when patients with HIV or AIDS present with various complaints, and also guides what prophylactic measures (e.g. antibiotics, antifungals) are administered to these patients. 

While CD8 T-cell, monocyte, platelet, and neutrophil counts may each be decreased for various reasons in patients with HIV and AIDS, the most substantial association between diminished cell count and HIV/AIDS is that of CD4 T-cells.

Example Question #1 : Circulatory And Respiratory Systems

How many lobes total are there in the human lungs?

Possible Answers:

Correct answer:

Explanation:

There are five lobes total in the human lungs: the right lung has three lobes (the upper lobe, the middle lobe, and the lower lobe) while the left lung has two lobes (the upper lobe and the lower lobe).

Example Question #2 : Circulatory And Respiratory Systems

What is the name for the topmost part of the lung?

Possible Answers:

The lingula

The hilum

The apex

The trachea

Correct answer:

The apex

Explanation:

The topmost part of the lungs is the apex. This area extends into the neck above the 1st rib and is the location auscultated for a diagnosis of a pancost tumor. The lingula of the lung is a small flap of the lowest part of the upper lobe of the left lung. The hilum is the entry point of the lung for the bronchi, pulmonary artery and vein, and nerves. The trachea is not a part of the lung at all; it is the cartilaginous tube that connects the pharynx and larynx to the lung.

Example Question #294 : General Biology

Which of the following lists of airway structures is in order from largest to smallest?

Possible Answers:

Trachea - alveoli - bronchiole - bronchi

Trachea - bronchi - bronchiole - alveoli

Trachea - bronchiole - bronchi - alveoli

Bronchi - trachea - bronchiole - alveoli

Correct answer:

Trachea - bronchi - bronchiole - alveoli

Explanation:

The largest airway structure is the trachea. This branches into two smaller bronchi, which enter the left and right lung and bifurcate further into smaller bronchioles. The bronchioles give way into the smallest structures of the lung, the tiny grape-like clusters of alveoli.

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