NCLEX : Cell Biology

Study concepts, example questions & explanations for NCLEX

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Example Questions

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Example Question #11 : Cell Biology

A human cell spends 90% of its lifetime in which phase of the cell cycle?

Possible Answers:

Interphase

Cytokinesis

Gap 1

Mitotic phase

Correct answer:

Interphase

Explanation:

90% of the cell cycle is spent in interphase. This time is also termed the "resting phase" as it is absorbing nutrients and replicating cellular elements in preparation for cell division. This phase includes the stages Gap 1 and Gap 2. Mitosis and cytokinesis, the final stages in cell division, are both relatively short compared to interphase, accounting for approximately 10% of the cell cycle.

Example Question #12 : Cell Biology

The chemotherapeutic agent vinblastine interferes with the assembly of microtubules. This is effective in the treatment of certain cancers due to what cellular effect?

Possible Answers:

Destabilization of cellular membranes

Inhibition of mitochondrial function

Disruption of the formation of mitotic spindles

Inhibition of DNA synthesis

Correct answer:

Disruption of the formation of mitotic spindles

Explanation:

Vinblastine and similar chemotherapeutic agents function by disrupting the formation and stability of microtubules in the cell. Because cell division is dependent on microtubule function, loss of microtubule integrity targets rapidly-reproducing cells such as cancer cells.

Example Question #11 : Cell Biology

A solution is said to be __________ when it contains a lower solute concentration than the cell.

Possible Answers:

Isotonic

Non-tonic

Hypotonic

Hypertonic

Correct answer:

Hypotonic

Explanation:

A hypotonic solution is one that contains solutes at a lower concentration than the cell. A cell, such as a red blood cell, will swell when exposed to a hypotonic solution as water moves into the cell to balance the osmotic gradient.

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