GRE Subject Test: Biology : Respiratory System

Study concepts, example questions & explanations for GRE Subject Test: Biology

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Example Questions

Example Question #1 : Respiratory System

What is the name of the structure that covers the airway while swallowing food?

Possible Answers:

Bronchus

Larynx

Trachea

Epiglottis

Correct answer:

Epiglottis

Explanation:

The oropharynx is capable of accepting both air and food from the mouth and nose. In the laryngopharynx, however, a crucial division occurs. Food, solids, and liquids are passed down the esophagus, while air travels through the trachea to the lungs. During swallowing, the entrance to the trachea, the larynx, must be covered so that food does not go through the trachea and enter the lungs. This is accomplished by the epiglottis, an elastic cartilage structure that covers the larynx during swallowing.

Example Question #1 : Understanding Alveoli

What is cell type forms the lining of the alveoli?

Possible Answers:

Respiratory

Apical

Endothelial

Basal

Epithelial

Correct answer:

Epithelial

Explanation:

The alveoli are lined with a single layer of squamous epithelial cells, which allow for easy diffusion of vital gases. Basal and apical cells refer to cells located at the bottom and top of structures, respectively. Endothelial cells line the circulatory system and blood vessels. There is no formal class of cells known as "respiratory cells."

Example Question #1 : Understanding Alveoli

The alveoli of the human lungs cluster together in alveolar sacs. These clusters are commonly said to resemble clusters of grapes, as the nearly spherical alveoli appear to bud away from "stems" (alveolar ducts). Which response best explains the alveoli's spherical shape?

Possible Answers:

Alveoli's spherical shape gives them the maximal amount of surface area possible for their volume; this large surface area allows for highly efficient gas exchange between the blood and the air in the lungs

The alveoli lie immediately adjacent to the capillaries around the lungs; the alveoli's spherical shape is nothing more than the result of the capillaries' generally round shape

The epithelial cells of the alveoli have a natural tendency to form spherical shapes; the alveoli's shape is a result of this tendency and is somewhat of a biological accident

Some extracellular matrix (ECM) material helps connect the alveoli to the capillaries; the presence of this material causes the alveoli to "pucker" into approximately spherical shapes

Correct answer:

Alveoli's spherical shape gives them the maximal amount of surface area possible for their volume; this large surface area allows for highly efficient gas exchange between the blood and the air in the lungs

Explanation:

The spherical or grape-like shape of the alveoli allows for maximum contact between the alveoli and the capillaries that surround them. The alveoli are filled with air that has been taken into the lungs from the environment, so a high surface area allows for maximum contact between air from the environment and capillaries. Oxygen rapidly diffuses through the exceptionally thin alveolar walls to the capillaries, which carry hemoglobin-containing blood cells that bind to the oxygen and shuttle it around the body. Blood cells also release carbon dioxide into the alveoli and lungs, which is why this process is called gas exchange. 

Capillaries are considerably smaller than alveoli; they surround the alveoli like a mesh, and are certainly not the cause of the alveoli's shape. Furthermore, though the cells of the alveoli do secrete extracellular matrix material, the cells affect the structure of the extracellular matrix, rather than the other way around. The shape of the alveoli is crucial to their function in gas exchange and cannot be considered an "accident," or the unexpected result of the shapes of other biological structures. 

Example Question #4 : Understanding Respiratory Structures

What type of epithelial tissue surrounds the alveoli?

Possible Answers:

Stratified squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Simple squamous epithelium

Correct answer:

Simple squamous epithelium

Explanation:

Alveoli are the site of gas exchange in the lungs. Because rapid diffusion of gases is necessary between the capillaries and the alveoli, a very thin epithelial layer is needed. As a result, alveoli use simple squamous epithelium so that gases can easily diffuses to and from the bloodstream.

Example Question #2 : Understanding Alveoli

Which of the following structures is found within the lungs and helps facilitate gas exchange?

Possible Answers:

Microvilli

Bronchi

Alveoli

Trachea

Secretory vesicles

Correct answer:

Alveoli

Explanation:

Alveoli are at the end of the respiratory pathway in humans, and act as a site of gas exchange (carbon dioxide and oxygen).

The path of air through the respiratory tract is: trachea, bronchi, bronchioles, alveoli. It is important to note that no gas exchange takes place in the bronchi, but does in the bronchioles, which are passageways that branch off from the main bronchi and eventually lead to alveolar ducts.

Micorvilli are found int he small intestine and act to increase the surface area in order to increase nutrient absorption. Secretory vesicles are used to transport proteins, hormones, and other molecules from a cell into the extracellular space.

Example Question #3 : Understanding Alveoli

The function of an alveolus is most evident in the basic anatomy of which type of alveolar cell?

Possible Answers:

The phagocytic alveolar macrophages

The very thin type 1 alveolar cells

The cuboidal or round type 2 alveolar cells

Clara cells

Correct answer:

The very thin type 1 alveolar cells

Explanation:

The vast majority of the surface area of an alveolus is made up of type 1 alveolar cells, which are squamous (flat), thin epithelial cells that allow rapid gas exchange between the air inside the alveoli and blood in the surrounding capillaries. The healthy adult human has millions of alveoli in his/her lungs, providing a huge total surface area across which gas can diffuse, letting oxygen into the bloodstream and carbon dioxide out.

Example Question #1 : Respiratory Anatomy

How many lobes does the right lung have?

Possible Answers:

One

Four

Two

Five

Three

Correct answer:

Three

Explanation:

The right lung contains three lobes: upper, middle, and lower. The left lungs contains two lobes: upper and lower. The left lung is designed to be smaller than the right in order to accommodate the heart, which is situated slightly to the left.

Example Question #1 : Respiratory System

Which of the following anatomical structures is found within the respiratory system?

Possible Answers:

Bronchiole

Alveoli

All of these structures are found within the respiratory system

Trachea

Pharynx

Correct answer:

All of these structures are found within the respiratory system

Explanation:

The respiratory system allows air to enter the lungs from the outside environment and facilitates gas exchange with the blood. Air initially enters through the mouth or nose, passes through the pharynx and larynx, and enters the trachea. From the trachea, air travels through branching structures from bronchi, to bronchiole, to alveoli. Gas exchange occurs between the air in the alveoli and the capillaries surrounding the alveoli.

Example Question #2 : Respiratory Anatomy

What respiratory structure connects the nasal passages and the mouth?

Possible Answers:

Pharynx

Larynx

Lungs

Trachea

Bronchioles

Correct answer:

Pharynx

Explanation:

The pharynx, located posteriorly (behind) the nasal passages and the mouth, is responsible for collecting the air that is taken in via the nose and mouth. The pharynx then passes the air to the larynx before it flows into the trachea. The trachea carries the air to the bronchioles, which end in terminal alveoli in the lungs.

Example Question #2 : Understanding Respiratory Structures

Which of the following is the correct path of air through the respiratory system?

Possible Answers:

Larynx, pharynx, bronchi, trachea, lungs

Bronchi, pharynx, larynx, trachea, lungs

Trachea, bronchi, larynx, pharynx, lungs

Larynx, trachea, bronchi, pharynx, lungs

Pharynx, larynx, trachea, bronchi, lungs

Correct answer:

Pharynx, larynx, trachea, bronchi, lungs

Explanation:

Air enters the body through the nose or mouth, and is transferred to the pharynx (the upper portion of the throat located at the back of the mouth). The larynx is commonly called the "voice box," and is the lower portion of the throat connected to the pharynx. From there, air enters the trachea and flows into the chest. The trachea branches into two bronchi, which continue to branch and divide as the air is carried into the lungs.

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