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Example Questions
Example Question #11 : Central Dogma Of Biology
All of the following organisms follow the central dogma except __________.
Algae
Botulism
HIV
Deathcap
HIV
The central dogma of biology reads that DNA goes to RNA which goes to protein. All of the following do that except for HIV, which uses reverse transcriptase in order to convert RNA to DNA which is going in reverse of the central dogma.
Example Question #11 : Central Dogma Of Biology
A gene is the DNA segment necessary to create a protein.
What sections of the DNA are included in a gene?
Poly-A tail and 5' cap
Length of DNA from a single chromosome
DNA encoding mRNA
Promoter region of DNA
DNA encoding mRNA and promoter region of DNA
DNA encoding mRNA and promoter region of DNA
Given the definition that a gene is the segment of DNA necessary to create a protein, we can immediately eliminate the choices of "Poly-A tail and 5' cap" and "Length of DNA from a single chromosome." Neither of these choices correspond to a segment of DNA: the first corresponds to segments of processed mRNA, and the second to the entire length of the DNA unsegmented. Neither "DNA encoding mRNA" or "Promoter region of DNA" can be correct, as they cannot function without the other, with the promoter region allowing proteins to prepare for transcription of the DNA-encoding mRNA to be produced.
Example Question #12 : Central Dogma Of Biology
What is the role of the promoter region of DNA in transcription?
To change the conformation of the DNA (i.e. double helix to parallel)
To be a template for the mRNA strand to be transcribed.
To initiate transcription of a particular gene
To open DNA downstream of the promoter region
To open DNA upstream of the promoter region
To initiate transcription of a particular gene
The promoter region of DNA does not interact with the shape of the DNA around it, eliminating all choices where change in DNA shape occurs. This leaves the answer choices of "To be a template for the mRNA strand," and "To initiate transcription of a particular gene." The promoter region is not transcribed to the mRNA that it initiates, leaving the correct answer, "To initiate transcription of a particular gene." The promoter region does this by attracting transcription factors necessary for recruitment of RNA polymerase.
Example Question #13 : Central Dogma Of Biology
Where does transcription take place?
Inside of the rough endoplasmic reticulum
On the outer cell membrane of the nuclear envelope
Inside of the mitochondria
On ribosomes
Inside of the nucleus
Inside of the nucleus
The central dogma of biology occurs inside of the nucleus from DNA to modified mRNA transcripts prepared to be exported to the cytoplasm. Since the nucleus is an organelle separated from the endoplasmic reticulum and the mitochondria, those answers can be eliminated. Translation occurs on ribosomes, not transcription. It is an important distinction that transcription occurs entirely within the membranes of the nucleus, and would not be found on the outer membrane of the nuclear envelope.
Example Question #14 : Central Dogma Of Biology
Which of the following is NOT true?
All answer choices are true.
DNA is transcribed to RNA.
DNA and RNA are made of nucleotides.
Proteins are made of amino acids.
RNA is transcribed into proteins.
RNA is transcribed into proteins.
In the central dogma of biology, DNA is transcribed to RNA, which is then translated to proteins. DNA and RNA are made up of nucleotides, and proteins are made up of amino acids. The only answer choice that does not fit this sequence is "RNA is transcribed into proteins." A correct statement would be that RNA is translated into proteins.
Example Question #15 : Central Dogma Of Biology
In the __________, DNA is __________ to RNA.
nucleus . . . transcribed
nucleus . . . translated
cytoplasm . . . translated
cytoplasm . . . transcribed
mitochondria . . . transcribed
nucleus . . . transcribed
Translation occurs on ribosomes in the cytoplasm or attached to the rough endoplasmic reticulum. No part of transcription or translation occurs in the mitochondria. Transcription occurs in the nucleus of the cell and therefore "nucleus . . . transcribed" is the correct answer.
Example Question #16 : Central Dogma Of Biology
In the __________, RNA is __________ to protein.
nucleus . . . transcribed
cytoplasm . . . transcribed
nucleus . . . translated
cytoplasm . . . translated
mitochondria . . . translated
cytoplasm . . . translated
Transcription occurs in the nucleus of the cell and is the process of using DNA to build RNA. Translation occurs on ribosomes in the cytoplasm and is the process of using RNA to build protein. No part of transcription or translation occurs in the mitochondria. Therefore "cytoplasm . . . translation" is the correct answer.
Example Question #17 : Central Dogma Of Biology
A transcription factor is a(n) __________ that binds to a specific sequence of __________, thereby controlling the rate of transcription.
corepressor . . . DNA
RNA sequence . . . DNA
protein . . . RNA
protein . . . DNA
coactivator . . . DNA
protein . . . DNA
A transcription factor is a protein that binds to a specific sequence of DNA, thereby controlling the rate of transcription. Transcription factors work by binding to DNA prior to transcription and act to either increase or decrease the rate of subsequent transcription processes. Transcription factors bind to enhancer or promoter regions and may attract corepressor or coactivator proteins to the binding site, but corepressors and coactivators are not themselves transcription factors.
Example Question #18 : Central Dogma Of Biology
What is the main enzyme that transcribes DNA into RNA?
Helicase
Primase
RNA Polymerase
DNA Polymerase I
DNA Polymerase III
RNA Polymerase
Both DNA polymerase I and DNA polymerase III play a role in the replication of DNA, but not in its transcription. Helicase acts to unwind the DNA strand. Primase synthesizes the RNA fragments necessary for DNA replication. RNA polymerase binds to DNA at the promoter region and builds mRNA along the template, therefore "RNA polymerase" is the correct answer.
Example Question #19 : Central Dogma Of Biology
What is the first amino acid in every protein made in a eukaryotic cell?
Methionine
Glycine
Glutamic Acid
Alanine
Cysteine
Methionine
While all of the answer choices are amino acids, only one corresponds to the "start" codon. All start codons correspond to the amino acid methionine, the most common being "AUG." Due to corresponding with the start codon, methionine will be the first amino acid laid down in every protein made in a eukaryotic cell.