Biochemistry : Identifying Specific Carbohydrate Functions

Study concepts, example questions & explanations for Biochemistry

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Example Questions

Example Question #153 : Identifying Biochemical Molecules

Upon examination, a patient is found to have low levels of glucose in his blood. Which of the following observation(s) might be found in this patient?

I. The patient is lethargic

II. Decreased levels of glycogen

III. Decreased levels of fatty acids

Possible Answers:

II only

I and III

I and II

I, II, and III

Correct answer:

I, II, and III

Explanation:

Glucose is a monosaccharide that is utilized for energy production in cells. Decrease in glucose levels in blood and tissues will lead to decreased production of energy (ATP) and, subsequently, will cause the person to be lethargic. Recall that glucose undergoes glycolysis to create products that will eventually undergo Krebs cycle and/or oxidative phosphorylation to generate ATP.

Glycogen is a storage molecule found typically in liver. It is made up of numerous glucose molecules bonded together by glycosidic bonds. If there is a decrease in blood glucose levels, liver initiates the breakdown of glycogen to individual glucose molecules and deposits these molecules in the blood; therefore, this patient’s liver will break down glycogen and create individual glucose molecules.

Fatty acid is another type of macromolecule used to synthesize energy. If there is a decrease in levels of glucose, fatty acids from adipose tissue and muscle will be mobilized and released into the blood. These fatty acids will now travel to tissues and supply energy (by generating ATP).

Example Question #3 : Identification By Function

Atkins diet is a special diet that involves low intake of carbohydrates. Which of the following molecules might be elevated in a person following the Atkins diet?

Possible Answers:

More than one of these

Blood glucose

Ketone bodies in blood

Glycogen stores in liver

Correct answer:

Ketone bodies in blood

Explanation:

Carbohydrates are first lines of energy source for tissues. If there is a decrease in the amount of carbohydrates, then other energy sources such as fatty acids and proteins are mobilized and undergo metabolism to produce energy. One of the byproducts of fatty acid metabolism are ketone bodies; therefore, a decrease in carbohydrates will lead to an increase in fatty acid metabolism and, subsequently, an increase in ketone bodies.

Glycogen stores will be depleted because liver will respond to the decreased glucose levels and break down glycogen to component glucose molecules. Low carbohydrate concentration will decrease blood glucose levels.

Example Question #4 : Identification By Function

In which cellular compartment is pyruvate carboxylase found?

Possible Answers:

Endoplasmic reticulum

Mitochondria

Nucleus

Golgi apparatus

Correct answer:

Mitochondria

Explanation:

Pyruvate carboxylase is an enzyme involved in gluconeogenesis, which is the generation of glucose from non-carbohydrate carbon substrates. This enzyme aids in the formation of PEP (phosphoenolpyruvate) from pyruvate. It converts pyruvate to oxaloacetate in the mitochondrion, requiring the hydrolysis of one molecule of ATP.

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