AP Biology : Nervous System

Study concepts, example questions & explanations for AP Biology

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Example Questions

Example Question #2 : Understanding Neurotransmitters

Which of the following is true regarding a synapse?

I. The neurotransmitter attaches to receptors on the presynaptic neuron

II. Propagation of the nerve signal is slowest at the synapse

III. Calcium ion channels located on the membrane of postsynaptic neuron facilitate the release of neurotransmitters

Possible Answers:

I only

II and III

II only

I and III

Correct answer:

II only

Explanation:

Neurotransmitters, such as acetylcholine, are chemical signals that transmit action potentials from one neuron to another. This process occurs at the synapse, where a neurotransmitter is released from the presynaptic neuron. This neurotransmitter travels across the synaptic cleft and binds to a receptor on the postsynaptic neuron. Statement I is thus false.

The rate of propagation of a nerve signal is limited by the synapse because neurotransmitters must diffuse across the gap; statement II is true.

Calcium ions are very important in the release of neurotransmitters. Voltage-gated calcium channels are located on the axon of the presynaptic neuron. When an action potential reaches the synapse, calcium ions are allowed to enter into the presynaptic neuron. This influx of calcium ions interacts with vesicles containing neurotransmitters and causes them to release their contents into the synaptic cleft. Statement III is false because calcium ion channels are located on the membrane of presynaptic neuron, not postsynaptic neuron.

Example Question #1 : Understanding Neurotransmitters

A postsynaptic neuron has undergone a mutation that renders its SNARE proteins nonfunctional. What is the result of this mutation?

Possible Answers:

None of the other answers

Action potentials are unable to propagate down the postsynaptic axon

Neurons are unable to maintain resting membrane potential

Neurons are unable to deliver neurotransmitter into the synaptic cleft

Neurons are unable to synthesize neurotransmitter

Correct answer:

Neurons are unable to deliver neurotransmitter into the synaptic cleft

Explanation:

The SNARE proteins are responsible for allowing vesicles filled with neurotransmitter to fuse with the cell membrane at the synaptic cleft, resulting in exocytosis. Without these proteins, the neurotransmitter cannot propagate the signal to any other cells.

Neurotransmitter synthesis occurs via translation or synthesis in the smooth endoplasmic reticulum, depending on the identity of teh molecule. Resting potential is determined by the sodium-potassium pump, and action potential propagation relies heavily on voltage-gated sodium channels and myelin.

Example Question #4 : Understanding Neurotransmitters

Which of the following types of molecules could potentially be a neurotransmitter?

I. Peptides

II. Gases

III. Monoamines

Possible Answers:

I, II, and III

I and III

III only

I and II

Correct answer:

I, II, and III

Explanation:

All of the choices could potentially be neurotransmitters.

Peptide neurotransmitters are proteins. An example of a peptide neurotransmitter is somatostatin. Nitric oxide is the most well-known gaseous neurotransmitter. Monoamines are molecules that contain an amine group connected to an aromatic ring. These molecules are derived from aromatic amino acids. Dopamine, norepinephrine, and epinephrine are very well-known monoamine neurotransmitters.  

Example Question #5 : Understanding Neurotransmitters

Which answer gives the two possible effects of a neurotransmitter on a postsynaptic neuron?

Possible Answers:

Excitatory or no effect

Apoptotic or no effect

Inhibitory or excitatory

Inhibitory or no effect

Correct answer:

Inhibitory or excitatory

Explanation:

Receptors on postsynaptic neurons are connected to ion channels. When the neurotransmitter binds to the receptor, the channel opens, making that neuron more or less likely to have an action potential depending upon which type of ion the channel allows to enter or exit the neuron. The result is either an excitatory postsynaptic potential (EPSP) or an inhibitory postsynaptic potential (IPSP).

Example Question #2 : Understanding Neurotransmitters

Which of the following is true regarding the parasympathetic nervous system?

Possible Answers:

It works to decrease heart rate and blood pressure

It works to funnel blood to the muscles in preparation for a fight-or-flight response

It works to elevate heart rate and blood pressure

It is a part of the central nervous system

It is a part of the somatic nervous system

Correct answer:

It works to decrease heart rate and blood pressure

Explanation:

The parasympathetic division of the autonomic nervous system promotes the "rest and digest mode." The somatic nervous system controls voluntary skeletal muscles, but the parasympathetic nervous system controls involuntary smooth & cardiac muscles. The neurons of the parasympathetic nervous system release acetylcholine, which is a neurotransmitter that leads to a decrease in heart rate and blood pressure. Results of increased parasympathetic activity include: decreasing blood flow to skeletal muscles, increasing blood flow to the gut, constricting pupils, and glycogenesis. 

Example Question #1 : Understanding Neurotransmitters

Which neurotransmitter is involved in muscle movement?

Possible Answers:

Dopamine

Glutamate

GABA

Acetylcholine

Serotonin

Correct answer:

Acetylcholine

Explanation:

The correct answer is ACh (acetylcholine) because it is involved with muscle contraction. It is released at the neuromuscular junction, the site where the neuron and muscle meet.

Example Question #41 : Neural Physiology

Which of the following may result from damage to the front lobe?

Possible Answers:

Auditory impairment

Numbness in the extremities

Visual impairment

Spastic muscle activity

Impairment of speech

Correct answer:

Impairment of speech

Explanation:

The brain is often divided into four lobes based on anatomy and physiology: the frontal lobe, parietal lobe, occipital lobe, and temporal lobe. Each lobe controls various aspects of cognition and motor skills. The frontal lobe is associated with reasoning, speech, movement, and emotions. The parietal lobe is associated with orientation and recognition. The occipital lobe is associated with visual processing. The temporal lobe is associated with auditory processing and memory.

Broca's area is a small region of the frontal lobe located in the left hemisphere. This region of the brain is responsible for generating speech and articulation. Damage to this region of the frontal lobe could cause speech impairment. In contrast, Wernicke's area is located in the temporal lobe and is associated with comprehension of speech.

Spastic muscle activity is not related to the brain, but results from injury to motor neurons spanning from the spinal cord to the limbs.

Example Question #42 : Neural Physiology

What occurs at a synapse?

Possible Answers:

A neuron releases hormones into the blood stream

A neuron communicates with its target cell via electrical or chemical stimulation

Nothing; synapses are layers of protection for neurons

Proteins on the axon of one neuron interface with proteins on dendrites of another

Correct answer:

A neuron communicates with its target cell via electrical or chemical stimulation

Explanation:

Synapses are special regions where a neuron releases a signal to its target cell. Most commonly this signal is chemical (neurotransmitters), but it can also be electrical. The synapse is a gap between the neurons, and does not allow for direct contact. Signals are released from the axon of one neuron and must traverse the synaptic cleft before interfacing with receptors on the target cell.

Neurons do not directly release hormones into the blood stream and synapses do not offer protection to neurons.

Example Question #43 : Neural Physiology

Which term is used to describe movement of an organism toward a light source?

Possible Answers:

Negative chemotaxis

Positive chemotaxis

Negative thermotaxis

Negative phototaxis

Positive phototaxis

Correct answer:

Positive phototaxis

Explanation:

Phototaxis is movement (taxis) in response to light (photo). Movement towards a source is positive; movement away from a source is negative. "Positive phototaxis" would be used to describe movement toward a light source.

Example Question #44 : Neural Physiology

Which statement is not true about glia?

Possible Answers:

Glial cells supply oxygen and nutrients to neurons

Glial cells are not neurons

Glial cells receive action potentials from dendrites

Glia help clear neurotransmitters from the synaptic cleft

Glial cells insulate neurons from each other

Correct answer:

Glial cells receive action potentials from dendrites

Explanation:

Glial cells are non-neuronal cells that support neuron activity. Their functions include physical support of neurons, supply oxygen and nutrients, and take up excess neurotransmitters. 

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