AP Biology : Cellular Division

Study concepts, example questions & explanations for AP Biology

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Example Questions

Example Question #4 : Understanding Meiosis

Which of the following statements regarding mitosis and meiosis is correct?

Possible Answers:

Mitosis results in higher genetic variability than meiosis

Mitosis only occurs in prokaryotes, including all bacteria, while meiosis occurs in higher life forms

None of the other answer choices are correct

In the human body, mitosis occurs in somatic cells while meiosis occurs in sex cells

Correct answer:

In the human body, mitosis occurs in somatic cells while meiosis occurs in sex cells

Explanation:

Both mitosis and meiosis occur in humans. Somatic cells (body cells) divide via mitosis, while gametes (sex cells) divide via meiosis. Because of actions such as crossing over, meiosis results in a higher genetic variability than mitosis.

Prokaryotes, such as bacteria, reproduce asexually, and are incapable of meiosis.

Example Question #2 : Understanding Meiosis

Which of the following chromosomal abnormalities is an example of monosomy?

Possible Answers:

Klinefelter syndrome

Turner syndrome

Edwards syndrome

Down syndrome

Correct answer:

Turner syndrome

Explanation:

Turner syndrome occurs when a person is missing one sex chromosome, and only has one X-chromosome. As a result, they will be female, and may suffer a variety of symptoms. This is an example of monosomy, in which a person only has one chromosome, when they should have two.

The other three choices are examples of trisomy. Klinefelter is an instance of sex-linked trisomy, with a karyotype of XXY. Down syndrome is cause by trisomy 21, and Edwards syndrome is caused by trisomy 18.

Example Question #1 : Understanding Meiosis

Non-disjunction can result in which of the following?

Possible Answers:

Both monosomy and trisomy

Trisomy

Monosomy

Neither monosomy, nor trisomy can be caused by non-disjunction

Correct answer:

Both monosomy and trisomy

Explanation:

Non-disjunction occurs when sister chromatids fail to separate during meiosis, leading subsequent daughter cells to have an unequal number of chromosomes. This can result in a cell having one extra chromosome (trisomy), or missing one chromosome (monosomy).

The following shows non-disjuction occuring in metaphase II of meiosis. "X" represents a chromosome, "|" represents a cell membrane, and "\" and "/" represent chromatids. When a sperm cell fuses with the egg formed to the left of the membrane (|), it will result in trisomy. When a sperm fuses with the egg to the right of the membrane (|), it will result in monosomy.

Metaphase I: X  X

Telophase I: X | X

Metaphase II: / \

Telophase II: / \ |

Example Question #397 : Ap Biology

Which of the following would result in a cell with an abnormal number of chromosomes after meiosis?

Possible Answers:

Nondisjunction

Recombination

Cleavage of the securin protein

Separation of sister chromatids

Correct answer:

Nondisjunction

Explanation:

Crossing over, or recombination, is a process that takes place in the earlier stages of meiosis and promotes genetic diversity. During recombination, genetic material is exchanged between two homologous chromosomes. The chromosomes ultimately contain the same amount of genetic material after recombination, and are properly separated during subsequent divisions.

The cleavage of the protein securin is actually what allows the sister chromatids to separate, a process that is essential to maintaining the correct number of chromosomes in each daughter cell.

Nondisjunction is the name given to the phenomenon in which separation of genetic material fails to occur. Either homologous chromosomes fail to separate properly in meiosis I, or sister chromatids fail to separate properly during meiosis II. The result of these nondisjunction events is one cell with an abnormally high number of chromosomes (for example trisomy) and one cell with an abnormally low number of chromosomes (for example monosomy).

Example Question #2 : Understanding Meiosis

Crossing over is an event that contributes to the non-identical nature of gametes. Which of the following is true regarding crossing over?

I. It occurs during prophase I

II. It involves exchange of genetic material between sister chromatids

III. It involves exchange of genetic material between homologous chromosomes

Possible Answers:

II

I

I and III

I and II

Correct answer:

I and III

Explanation:

Crossing over occurs during prophase of meiosis I (prophase I). This process requires tetrad formation, where the homologous chromosomes (with their sister chromatids) pair with each other. Following tetrad formation, the genetic material from one homologous chromosome can be exchanged with that of the other. This exchange of genetic material leads to genetic recombination and results in production of non-identical gametes. Crossing over occurs only between homologous chromosomes. Sister chromatids are situated to form a single chromosome; crossing over does not include recombination of genetic material within a single chromosome.

Remember that crossing over is not a mutation and is a completely natural process for every sexually reproducing organism.

Example Question #2 : Understanding Meiosis

Independent assortment of traits on different chromosomes is due to the random alignment of different pairs of homologues. This alignment occurs during which of the given phases?

Possible Answers:

Prophase II

Metaphase II

Metaphase I

Prophase I

Correct answer:

Metaphase I

Explanation:

Remember that the law of independent assortment states that genes on different chromosomes are passed independently of one another to offspring. This phenomenon results from the random alignment of the chromosomes along the metaphase plate. This random alignment allows genes to be segregated independently, and occurs during metaphase I.

Metaphase II involves the alignment of single chromosomes along the metaphase plate for segregation of identical sister chromatids. Remember that independent assortment is only valid for genes on different chromosomes. Genes on the same chromosomes are not passed independently of one another from parent to offspring.

Independent assortment can, thus, only occur during metaphase I, since this phase involves alignment of independent, non-identical chromosomes.

Example Question #11 : Understanding Meiosis

Cells containing only one homologue of each chromosome would be produced following which of the following processes?

Possible Answers:

Mitosis

Meiosis I

S phase

Both meiosis I and mitosis

Correct answer:

Meiosis I

Explanation:

For this question, remember that a cell containing only one homologue is a haploid cell. Cells containing two homologous chromosomes are considered diploid.

Following the S phase and mitosis, the cells are diploid because they contain pairs of homologous chromosomes.

Following meiosis I, however, the daughter cells are haploid because they contain only one homologue. These homologues still consist of two identical sister chromatids, which will be separated following meiosis II, but the halving of genetic material during meiosis I still generates haploid daughter cells.

Example Question #12 : Understanding Meiosis

Which of the following is true regarding meiosis I and meiosis II?

Possible Answers:

Both involve reductional division

The G2 phase precedes both

Sister chromatids separate in anaphase of meiosis I, but not in meiosis II

Both produce haploid cells

Correct answer:

Both produce haploid cells

Explanation:

Meiosis I involves the separation of homologous chromosomes, while meiosis II involves the separation of sister chromatids. The G2 phase precedes meiosis I or mitosis, but does no precede meiosis II. Interkinesis is the period that separates meiosis I and meiosis II.

Meiosis I results in two daughter cells, each with only one copy of each chromosome, from a parent cell with two copies of each chromosome. The parent cell is diploid, while the daughter cells are haploid. This is known as reductional division because the daughter cell contain less genetic material than the parent cell. Meiosis II results in four daughter cells from two parent cells. Each parent contains one copy of each chromosome, and each daughter cell also contains one copy of each chromosome (although the material is stored on a single chromatid). Since both parent and daughter cells contain the same amount of genetic information, this is considered an equational division. The daughter cells of both meiosis I and meiosis II contain only one copy of each chromosome, as homologous pairs have been separated. Both meiosis products are thus considered haploid, making this the correct answer.

Example Question #13 : Understanding Meiosis

How many chromosomes does a human germ cell contain during metaphase I and telophase II, respectively?

Possible Answers:

There are 23 chromosomes during metaphase I and 23 chromosomes during telophase II

There are 46 chromosomes during metaphase I and 23 chromosomes during telophase II

There are 23 chromosomes during metaphase I and 46 chromosomes during telophase II

There are 46 chromosomes during metaphase I and 46 chromosomes during telophase II

Correct answer:

There are 46 chromosomes during metaphase I and 46 chromosomes during telophase II

Explanation:

For this question you have to carefully track the chromosomes through meiosis. A human cell in metaphase I will have formed the tetrads and would have aligned the genetic material along the metaphase plate. The sister chromatids are still attached to one another, so they only count as one chromosome per pair of chromatids. There are a total of 46 chromosomes in metaphase I, each comprised of two sister chromatids. There are 23 homologous pairs, each containing two complete chromosomes.

During telophase II, the cell is in a haploid state. The homologous pairs have been separated during anaphase I, such that each cell contains 23 complete chromosomes. Each chromosome is then broken into its chromatids, such that the total number of chromosomes represented during anaphase II is 46, with each chromatid representing a chromosome. If each of the chromosomes still had its sister chromatid, then the total number of chromosomes would be 23. Telophase II follows anaphase II. The 46 chromatids are sequestered to opposite sides of the cell, but the cell has not yet divided. A cell in telophase II is haploid, containing only one copy of each homologous chromosome, but contains two chromatids for each copy. The total number of chromosomes in a telophase II cell is thus 46. As soon as the cell completes cytokinesis, and two daughter cells are formed, they become haploid cells with 23 chromosomes each.

Example Question #12 : Understanding Meiosis

In vertebrates, sperm cells typically contribute which of the following a new organism?

Possible Answers:

All of the cytoplasm of the zygote

A complete zygote

Diploid sex chromosomes

Nuclei

A complementary haploid portion of chromosomes

Correct answer:

A complementary haploid portion of chromosomes

Explanation:

In most vertebrates, sperm cells join with egg cells to form a zygote. Each cell produces a haploid complement of chromosomes in order to form the zygote. The result is a new organism with a full set of maternal chromosomes and a full set of paternal chromosomes.

When a sperm joins with an egg, only the nucleus of the sperm enters to egg to form the zygote. The nuclear envelope is then altered, allowing the paternal DNA to intermix with the maternal DNA in the zygote nucleus. The sperm does not contribute a nucleus (only genetic material), cytoplasm, or diploid copies of any chromosome.

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