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Example Questions
Example Question #11 : Understanding Hardy Weinberg Assumptions And Calculations
A person carrying two recessive alleles of a specific gene has a greater likelihood of developing lung cancer. The frequency of the dominant allele in a population is eighty-seven percent.
Based on the Hardy-Weinberg principle, what is the expected frequency of homozygous recessive genotype in this population?
The Hardy-Weinberg equations can be used to determine the expected frequency of genes and genotypes within a population, provided that only Mendelian segregation and recombination of alleles are at work. This is calculated mathematically using the equations:
Let's start with what we know and how it relates to these equations. We are told that the dominant allele frequency () is 87%, and then asked to find the frequency of homozygous recessive individuals ().
Known:
Unknown:
Use the second Hardy-Weinberg equation to solve for .
Square this value for find the frequency of homozygous individuals.
Example Question #13 : Population Genetics
Hearing loss is caused by the inheritance of different genetic alleles: GM and GJ. The expected frequency of a GM allele is 90% in a given population.
Based on the Hardy-Weinberg principle, what is the expected frequency of genotype GMGJ in the next generation of this population?
The Hardy-Weinberg equations can be used to determine the expected frequency of genes and genotypes within a population, provided that only Mendelian segregation and recombination of alleles are at work. This is calculated mathematically using the equations:
In this example, the expected frequency to be solved for is the heterozygote GMGJ that is represented by the component of the equation. We are told the frequency of the GM allele in the population, allowing us to solve for the frequency of the GJ allele. It is not necessary to know which allele is dominant and which is recessive in this particular question since we are dealing only with genotypes (phenotype is irrelevant).
Using these values, we can calculate the value of .
Example Question #11 : Understanding Hardy Weinberg Assumptions And Calculations
A population of beetles exists in which black coloration is dominant to white. If there are 36 white beetles in a population of 100 beetles, what is the dominant allele frequency?
Unable to determine from the given information
There are multiple ways to solve this problem, but the easiest is to use the Hardy-Weinberg equations:
We are told the frequency of white beetles in the population. Using this value, we can find the recessive allele frequency. is equivalent to the homozygous recessive genotype frequency.
Use this value to solve for the dominant allele frequency.
Example Question #14 : Understanding Hardy Weinberg Assumptions And Calculations
In a given population of snails, spiral shells are dominant to round shells. If 36% of the population is homozygous for the spiral shell allele, what percentage of the population is heterozygous?
We can use the Hardy-Weinberg equations to solve this problem.
We know that spiral shells are dominant, and that 36% of the population is homozygous for the spiral allele. This tells us that 36% of the population is homozygous dominant. The term corresponds to the homozygous dominant percentage.
is the dominant allele frequency. Now we can solve for , the recessive allele frequency.
The term will give us the frequency of heterozygotes.
48% of the population is heterozygous.
Example Question #14 : Understanding Hardy Weinberg Assumptions And Calculations
If four percent of the population is homozygous recessive for the trait that carries dimples (recessive), what is the fractional frequency of the dominant allele?
Using the Hardy-Weinberg law to solve for allele frequency in populations, you can solve for the answer using the following two equations.
p is the fractional frequency of the dominant allele, q is the fractional frequency of the recessive allele, and q2 is the fraction of the population that is homozygous recessive. q2 is given in the question to be 0.04 (or 4%).
Example Question #13 : Understanding Hardy Weinberg Assumptions And Calculations
Which of the following is not a Hardy-Weinberg assumption?
There is no mutation
There is nonrandom mating
Population size is large enough to prevent random drift
There is no migration
There is no natural selection
There is nonrandom mating
Random mating is a Hardy-Weinberg assumption, not nonrandom. The remaining answer choices are all standard assumptions for Hardy-Weinberg equilibrium. Nonrandom mating would allow certain alleles to be preferentially passed down over generations.
Example Question #141 : Evolution And Genetics
Which of the following are assumptions made by the Hardy-Weinberg principle?
Large population size
No migration, mutation, and selection
All of these
Random mating and sexual reproduction
All of these
The Hardy-Weinberg principle is a theory that describes how allele frequencies may change within a population absent of evolutionary mechanisms. The theorem is based on certain assumptions regarding the population in question. These assumptions include random mating, large population size, sexual reproduction, and the absence of migration, mutation and selection. It is exceedingly rare for all the Hardy-Weinberg assumptions to be met in nature, but this theory is a tool used to study allele frequencies within populations.
Example Question #22 : Understanding Hardy Weinberg Assumptions And Calculations
In the Hardy-Weinberg theorem, refers to what?
The frequency of the dominant allele
The frequency of the homozygous recessive genotype
The frequency of the homozygous dominant genotype
The frequency of the recessive allele
The frequency of the dominant allele
In the Hardy-Weinberg theory, the two equations used are:
Here, refers to the frequency of the dominant allele and refers to the frequency of the recessive allele. Subsequently, refers to the frequency of the homozygous dominant genotype, refers to the frequency of the homozygous recessive genotype, and refers to the frequency of the heterozygous genotype.
Example Question #142 : Evolution And Genetics
Which of the following are deviations from the Hardy-Weinberg equilibrium?
Mutation and migration
Random mating and mutation
Random mating only
Mutation only
Migration only
Mutation and migration
In Hardy-Weinberg equilibrium, deviations are violations of the assumptions of the Hardy-Weinberg theory. The assumptions of the Hardy-Weinberg theoru include random mating, large population size, sexual reproduction, and the absence of migration, mutation and selection. Therefore, deviations from the Hardy-Weinberg equilibrium from the options are mutation and migration.
Example Question #143 : Evolution And Genetics
What is the best explanation for a population being described as an evolutionary unit?
A population's gene pool remains the same throughout time
Populations can evolve, not individuals
Natural selection only involves individuals, not populations
Natural selection only occurs across species
Genetic changes occur only in populations
Populations can evolve, not individuals
The genetic make up of populations can be measured over time. While genetic changes only occur at the individual level, it is only populations that evolve since genetic changes take many generations to develop into phenotypic changes that may be observed as changing allele frequencies over time.
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