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Patient Parameters And Laboratory Measures Practice Test
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Q1
A 70-year-old male (weight 76 kg) on warfarin for a mechanical aortic valve presents for INR check after starting an antibiotic. Current medications: warfarin 6 mg PO daily, trimethoprim-sulfamethoxazole DS 1 tablet PO BID (started 5 days ago for UTI), amlodipine 5 mg PO daily, tamsulosin 0.4 mg PO nightly. PMH: mechanical aortic valve, BPH, HTN. Allergies: NKDA. Labs: INR 6.2 (goal 2.5–3.5), Hgb 13.5 g/dL, platelets 240,000/mm$^3$, AST 30 U/L, ALT 28 U/L, SCr 1.1 mg/dL; no signs of bleeding. What is the next best step in managing this patient's anticoagulation therapy?
A 70-year-old male (weight 76 kg) on warfarin for a mechanical aortic valve presents for INR check after starting an antibiotic. Current medications: warfarin 6 mg PO daily, trimethoprim-sulfamethoxazole DS 1 tablet PO BID (started 5 days ago for UTI), amlodipine 5 mg PO daily, tamsulosin 0.4 mg PO nightly. PMH: mechanical aortic valve, BPH, HTN. Allergies: NKDA. Labs: INR 6.2 (goal 2.5–3.5), Hgb 13.5 g/dL, platelets 240,000/mm$^3$, AST 30 U/L, ALT 28 U/L, SCr 1.1 mg/dL; no signs of bleeding. What is the next best step in managing this patient's anticoagulation therapy?