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MCAT Biological and Biochemical Foundations of Living Systems Flashcards: 2c Cancer Cell Cycle Control

Study 2c Cancer Cell Cycle Control in MCAT Biological and Biochemical Foundations of Living Systems with focused flashcards that help you recognize the idea, recall the key rule, and apply it in practice-style prompts.

QUESTION

What is the key role of p21 in cell cycle control?

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ANSWER

Cyclin-dependent kinase inhibitor that enforces G1G_1 arrest. p21 blocks cyclin-CDK activity to prevent progression from G1G_1 to S phase during stress.

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MCAT Biological and Biochemical Foundations of Living Systems: Foundational Concept 2: Cells and Cellular Organization

You are hereCancer Biology and Loss of Cell Cycle Control (2C)25 cards

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What this deck covers

This deck focuses on 2c Cancer Cell Cycle Control, giving you a quick way to review the definitions, rules, and examples that matter most for MCAT Biological and Biochemical Foundations of Living Systems.

How to use these flashcards

Work through these flashcards in short sessions. Try to answer each prompt before flipping the card, then revisit any cards you miss until the explanation feels automatic.

Practice questions

1 of 50Practice questions for this set
A lab studied the Rb–E2F pathway in a cancer cell line. In normal cells, hypophosphorylated Rb binds E2F and limits transcription of S-phase genes; phosphorylation of Rb by cyclin D–CDK4/6 releases E2F. The cancer line expresses an Rb truncation that cannot bind E2F. When treated with a CDK4/6 inhibitor, the cancer cells show little change in S-phase gene expression, while a control line with intact Rb shows decreased S-phase gene expression and reduced proliferation. Which outcome is most consistent with these findings?
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