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MCAT Biological and Biochemical Foundations of Living Systems Flashcards: 1b Gene Regulation Eukaryotes

Study 1b Gene Regulation Eukaryotes in MCAT Biological and Biochemical Foundations of Living Systems with focused flashcards that help you recognize the idea, recall the key rule, and apply it in practice-style prompts.

QUESTION

What is the direct effect of histone acetylation on chromatin structure?

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ANSWER

Decreases histone-DNA affinity, opening chromatin. Acetyl groups reduce the electrostatic attraction between histones and DNA, promoting a more open structure for gene activation.

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MCAT Biological and Biochemical Foundations of Living Systems: Foundational Concept 1: Biomolecules and Metabolism

You are hereRegulation of Gene Expression in Eukaryotes (1B)24 cards

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What this deck covers

This deck focuses on 1b Gene Regulation Eukaryotes, giving you a quick way to review the definitions, rules, and examples that matter most for MCAT Biological and Biochemical Foundations of Living Systems.

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Work through these flashcards in short sessions. Try to answer each prompt before flipping the card, then revisit any cards you miss until the explanation feels automatic.

Practice questions

1 of 50Practice questions for this set
A lab tests whether a putative silencer element (S) represses transcription of the eukaryotic gene GATA4. A luciferase reporter is driven by the GATA4 minimal promoter (P) alone or by P plus S cloned upstream. Cells are transfected with either an empty vector or a plasmid expressing the transcription factor REST. Results after 24 hours are shown: Condition 1: P only + empty vector → 100% luciferase Condition 2: P+S + empty vector → 95% luciferase Condition 3: P only + REST → 90% luciferase Condition 4: P+S + REST → 25% luciferase Based on the setup, which outcome is most likely if S is mutated so that REST can no longer bind, while all other sequences remain unchanged?
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