Temperature Control And Stability Practice Test

At an outpatient clinic, a vaccine coordinator discovers the refrigerator temperature log shows 12°C (54°F) overnight for approximately 10 hours due to a malfunction. The unit contains inactivated influenza vaccine and hepatitis B vaccine, both labeled for storage at 2°C to 8°C (36°F to 46°F) and protection from freezing. The clinic is scheduled to administer doses this morning. What action should the pharmacist take regarding this storage issue?

In a retail pharmacy travel consult, a 62-year-old man (80 kg) with stable angina is taking sublingual nitroglycerin 0.4 mg tablets as needed for chest pain. He is traveling to a desert location where daytime temperatures may reach 40°C (104°F) and plans to keep the tablets in his car for convenience. Nitroglycerin sublingual tablets should be stored at controlled room temperature 20°C to 25°C (68°F to 77°F) in the original, tightly closed glass container and protected from heat, moisture, and light; potency loss can lead to reduced symptom relief. Which recommendation ensures optimal stability for this drug?