NAPLEX Flashcards: Pharmacogenomics

Study Pharmacogenomics in NAPLEX with focused flashcards that help you recognize the idea, recall the key rule, and apply it in practice-style prompts.

QUESTION

Which phenotype corresponds to increased function due to duplication or increased-activity alleles?

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ANSWER

Ultrarapid metabolizer (UM). Gene duplications or gain-of-function variants enhance enzyme activity, accelerating drug metabolism and potentially reducing efficacy.

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NAPLEX: Foundational Knowledge For Pharmacy Practice

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What this deck covers

This deck focuses on Pharmacogenomics, giving you a quick way to review the definitions, rules, and examples that matter most for NAPLEX.

How to use these flashcards

Work through these flashcards in short sessions. Try to answer each prompt before flipping the card, then revisit any cards you miss until the explanation feels automatic.

Practice questions

1 of 36Practice questions for this set
A 27-year-old Southeast Asian female (55 kg) is prescribed carbamazepine for trigeminal neuralgia. Current medications: none. Pharmacogenomic results: HLA-B*15:02 positive. Labs: serum creatinine 0.7 mg/dL, alanine aminotransferase 16 units/L. Allergies: none. Which medication is most appropriate for this patient given their genetic profile?
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