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Stereochemistry and Isomerism (5B) Practice Test

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Q1

A retinal-analog probe exists as geometric isomers about a C=C bond: Molecule C (cis) and Molecule T (trans). In a membrane-binding assay, Molecule T shows higher partitioning into lipid bilayers, while Molecule C shows reduced packing compatibility. Which statement best describes the stereochemical basis for the observed difference?

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