MCAT Biology : Systems Biology and Tissue Types

Study concepts, example questions & explanations for MCAT Biology

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Example Questions

Example Question #2 : Other Muscle Concepts

Duchenne Muscular Dystrophy is an X-linked recessive genetic disorder, resulting in the loss of the dystrophin protein. In healthy muscle, dystrophin localizes to the sarcolemma and helps anchor the muscle fiber to the basal lamina. The loss of this protein results in progressive muscle weakness, and eventually death.

In the muscle fibers, the effects of the disease can be exacerbated by auto-immune interference. Weakness of the sarcolemma leads to damage and tears in the membrane. The body’s immune system recognizes the damage and attempts to repair it. However, since the damage exists as a chronic condition, leukocytes begin to present the damaged protein fragments as antigens, stimulating a targeted attack on the damaged parts of the muscle fiber. The attack causes inflammation, fibrosis, and necrosis, further weakening the muscle.

Studies have shown that despite the severe pathology of the muscle fibers, the innervation of the muscle is unaffected.

The “basal lamina” refers to __________.

Possible Answers:

the extracellular matrix around the muscle fiber

the muscle fiber cytoplasm

the region of the muscle closest to the tendon

the outer covering of the muscle body

the point of the sarcolemma closest to a synapse

Correct answer:

the extracellular matrix around the muscle fiber

Explanation:

The muscle fiber cytoplasm is the sarcoplasm. The outer covering of the muscle body is the epimysium. The region of the muscle closest to the tendon and the region of sarcolemma near the synapse do not have technical names that you need to know for the MCAT, nor do they make sense as answer choices; we are looking for something that the sarcolemma must be anchored to. The basal lamina is the extracellular matrix surrounding the muscle fiber, made up largely of collagen, that connects each muscle fiber to its neighbors and helps them contract in unison.

Example Question #2 : Other Muscle Concepts

Which of the following muscles is an antagonist for the biceps brachii?

Possible Answers:

Brachioradialis

Biceps femoris

Triceps brachii

Brachialis

Correct answer:

Triceps brachii

Explanation:

An antagonist is defined as the muscle that strecthes when another muscle (the agonist) is contracting. When the antagonist contracts, it will stretch the agonist and move the bone in the opposite direction.

The biceps brachii is responsible for flexion of the forearm, while the triceps brachii is responsible for the extension of the forearm. As a result, we say that the triceps brachii is the antagonist of the biceps brachii.

Example Question #281 : Biology

The masseter is the most prominent muscle involved in eating food. It is responsible for elevating the jaw during mastication. The temporalis is a muscle located on the outside of the temporal bone. It also elevates the mandible during the chewing of food.

Based on this information, how would you describe the temporalis in relation to the masseter?

Possible Answers:

The temporalis is the origin of the masseter.

The temporalis is the synergist of the masseter.

The temporalis is the insertion of the masseter.

The temporalis is the antagonist of the masseter.

Correct answer:

The temporalis is the synergist of the masseter.

Explanation:

Synergistic muscles assist agonists by properly positioning the insertion bone or stabilizing the origin bone. This cooperation by multiple muscles allows for better movement and posture. Since the temporalis assists in raising the jaw with the masseter, we say that the temporalis is the synergist of the masseter.

Example Question #81 : Muscles And Myocytes

During muscle contraction, which parts of a sarcomere change in length?

Possible Answers:

The H zone and myosin

The I band and A band

The H zone and I band

The H zone and actin

The A band and H zone

Correct answer:

The H zone and I band

Explanation:

During muscle contraction, the H zone and I band contract, decreasing in length. The A band never changes in length. Also, while actin and myosin myofilaments slide over each other, their length does not change either.

Example Question #302 : Mcat Biological Sciences

Which type of muscle has both striations and multiple nuclei?

Possible Answers:

Cardiac muscle

Both skeletal muscle and cardiac muscle

Skeletal muscle

Smooth muscle

Both skeletal muscle and smooth muscle

Correct answer:

Skeletal muscle

Explanation:

There are three primary types of muscle tissue: skeletal, smooth, and cardiac.

Skeletal muscle and cardiac muscle are highly organized, with their contractile filaments arranged into sarcomeres. This organization results in a "striped" look on the cells, known as striations. Smooth muscle contains the same contractile filaments, but lacks the sort of highly organized structure found in the other two muscle types. As a result, smooth muscle is not striated.

Smooth muscle and cardiac muscle are generally mononucleate, meaning that each cell has only on nucleus. In contrast, skeletal muscle cells contain multiple nuclei.

The correct answer is that skeletal muscle is striated and contains multiple nuclei per cell.

Example Question #81 : Muscles And Myocytes

Which of the following answer options is not a function of the sarcolemma?

Possible Answers:

Controls the iron levels of cardiac tissue

Creates an ion potential across the muscle surface

Controls the tonic state of myocytes

Allows attachment sites for communication hormones

Creates T-tubules from invaginations along the membrane

Correct answer:

Controls the iron levels of cardiac tissue

Explanation:

The sarcolemma is the specialized cell membrane of a myocyte, or muscle cell. It performs all of the functions of a non-specialized plasmolemma, and forms T-tubules, which are important for muscle contraction.

Example Question #81 : Muscles And Myocytes

Which is not a function of muscle tissue?

Possible Answers:

Leverage

Thermoregulation

Locomotion

Motion

Peristalsis

Correct answer:

Leverage

Explanation:

The primary functions of muscle tissue are motion and locomotion (movement in relation to the body, and movement of the entire body). Muscle is also responsible for the shiver response, used in thermoregulation. Finally, smooth muscles move substances through the body in the process known as peristalsis.

Leverage is a function primarily accomplished by bone.

Example Question #81 : Musculoskeletal System And Muscle Tissue

What type of muscle cell is quadrangular, and features intercalated disks and multiple nuclei?

Possible Answers:

Skeletal muscle

None of the other answers

Smooth muscle

Cardiac muscle

Thick muscle

Correct answer:

None of the other answers

Explanation:

None of the answer options satisfy all of the criteria given in the question. Cardiac muscle cells have intercalated discs, but are mononucleate.

Example Question #82 : Musculoskeletal System And Muscle Tissue

A doctor oberves a teenager who noticed that one of his legs is about two inches longer than the other. He also sees that the patient had broken one of his legs when he was 8 years old, but the patient's notes don't indicate which leg. What conclusion is the doctor likely to come to?

Possible Answers:

The patient broke the longer leg on the periosteum.

The patient broke the longer leg on the epiphyseal plate.

The patient broke the shorter leg on the epiphyseal plate.

The patient broke the shorter leg on the diaphysis.

The patient broke the longer leg in the diaphysis.

Correct answer:

The patient broke the shorter leg on the epiphyseal plate.

Explanation:

The epiphyseal plate is the site of longitudinal growth in bones. The patient likely broke the leg along the plate, which caused it to grow less than the other leg.

Example Question #1 : Bone Development And Growth

A fetal rat's femoral cartilage is injected with a marker prior to endochondral ossification. The marker becomes deactivated as the cartilage is converted to bone. In which part of the femur would we expect to see a high concentration of the marker once the rat reaches adulthood?

Possible Answers:

In the spongy bone of the diaphysis

On the articular surface of the bone

In the compact bone of the diaphysis

Within the medullary cavity

Correct answer:

On the articular surface of the bone

Explanation:

The first important concept to understand for this question is the process of endochondral ossification. In this process, cartilage is converted into bone during the early life of an organism. Since the question specifies that the rat has reached adulthood, it must refer to the parts of the final bone product that remain as cartilage once endochondral ossification is complete.

Spongy bone and compact bone in the diaphysis have already ossified, and the medullary cavity contains bone marrow and adipose. To find cartilage in any of these regions would indicate a developmental abnormality.

The ends of bones that are in contact with other bones are protected from frictional damage by articular cartilage. Articular cartilage is essential to maintaining healthy joint function. Deterioration of this cartilage results in arthritis, or inflammation in the joints.

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